3-(4-IODOPHENYL)PROPIONIC ACID
- CAS No.
- 1643-29-4
- Chemical Name:
- 3-(4-IODOPHENYL)PROPIONIC ACID
- Synonyms
- 3-(4-IODOPHENYL)PROPANOIC ACID;4-Iodohydrocinnamic acid;3-(4-Iodphenyl)propionsSre;4-Iodo-benzenepropanoic acid;3-(4-Iodphenyl)propionicacid;Benzenepropanoic acid, 4-iodo-;3-(4-IODOPHENYL)PROPIONIC ACID
- CBNumber:
- CB0433006
- Molecular Formula:
- C9H9IO2
- Molecular Weight:
- 276.07
- MDL Number:
- MFCD00017597
- MOL File:
- 1643-29-4.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-Iodo-benzenepropanoic acid 98% | AS85340 | 1g | $33 |
| 4-Iodo-benzenepropanoic acid 98% | AS85340 | 5g | $123 |
| 3-(4-Iodophenyl)propanoic acid 98% | OR6478 | 250mg | $21 |
| 4-Iodo-benzenepropanoic acid 98% | AS85340 | 25g | $325 |
| 3-(4-Iodophenyl)propanoic acid 98% | OR6478 | 1g | $30 |
| More product size | |||
| Melting point | 140-142°C |
|---|---|
| Boiling point | 335.4±17.0 °C(Predicted) |
| Density | 1.775±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C(protect from light) |
| form | solid |
| pka | 4.61±0.10(Predicted) |
| color | White to off-white |
| CAS DataBase Reference | 1643-29-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
| Hazard Codes | Xi |
| HazardClass | IRRITANT |
| HS Code | 2916399090 |
3-(4-IODOPHENYL)PROPIONIC ACID price More Price(49)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS85340 | 4-Iodo-benzenepropanoic acid 98% | 1643-29-4 | 1g | $33 | 2026-06-04 | Buy |
| Activate Scientific | AS85340 | 4-Iodo-benzenepropanoic acid 98% | 1643-29-4 | 5g | $123 | 2026-06-04 | Buy |
| Apolloscientific | OR6478 | 3-(4-Iodophenyl)propanoic acid 98% | 1643-29-4 | 250mg | $21 | 2026-06-04 | Buy |
| Activate Scientific | AS85340 | 4-Iodo-benzenepropanoic acid 98% | 1643-29-4 | 25g | $325 | 2026-06-04 | Buy |
| Apolloscientific | OR6478 | 3-(4-Iodophenyl)propanoic acid 98% | 1643-29-4 | 1g | $30 | 2026-06-04 | Buy |
3-(4-IODOPHENYL)PROPIONIC ACID Chemical Properties,Uses,Production
Uses
p-Iodophenylpropionic acid is a carboxylic acid derivative and can be used as a biochemical reagent.
Synthesis
501-52-0
1643-29-4
The general procedure for the synthesis of 3-(4-iodophenyl)propionic acid from hydrogenated cinnamic acid is as follows: 1. Preparation of Intermediate 1: A mixture of H2SO4 (1.25 mL), water (12.5 mL) and AcOH (25 mL) was added to a 250 mL flask. Subsequently 3-phenylpropionic acid (3.00 g, 20.0 mmol), iodine (1.40 g, 5.5 mmol) and KIO3 (0.98 g, 4.6 mmol) were added. 2. the reaction mixture was heated to reflux and a solution of AcOH (25 mL) with iodine (1.40 g, 5.5 mmol) was added in portions, 5 mL at a time. the color of the solution gradually changed from purple to orange during the reaction. 3. After the reaction was carried out for 3 hours, when the color no longer changed, the reaction mixture was cooled to room temperature and the reaction was subsequently quenched with 1 M NaHSO3 solution. 4. Water was added to the reaction mixture and extracted with EtOAc. The organic phases were combined, washed with brine, dried over MgSO4 and concentrated in vacuum. 5. The crude product (4.15 g, 75% yield) containing a small amount of starting material and by-products was recrystallized by petroleum ether to give 1.83 g of pure white crystalline product (33% yield). Rf value: 0.10 (EtOAc:hexane, 1:4); 1H NMR (CDCl3) δ 7.62-7.59 (m, 2H), 6.97-6.95 (m, 2H), 2.92-2.87 (t, 2H, J = 7.5 Hz), 2.68-2.63 (t, 2H, J = 7.5 Hz); 13C NMR (CDCl3) δ 178.5, 139.7, 137.6, 130.4, 91.6, 35.2, 30.0.
References
[1] Patent: WO2010/12650, 2010, A1. Location in patent: Page/Page column 38
[2] Chemistry - A European Journal, 2009, vol. 15, # 10, p. 2278 - 2288
[3] Journal of the American Chemical Society, 2009, vol. 131, # 47, p. 17500 - 17521
[4] European Journal of Organic Chemistry, 2015, vol. 2015, # 27, p. 5919 - 5924
[5] Patent: WO2016/201125, 2016, A1. Location in patent: Page/Page column 19
3-(4-IODOPHENYL)PROPIONIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14034 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10817 | 58 |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29780 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34526 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52693 | 58 |
| Suzhou Victorypharm Co.,Ltd. | +86-13916956214 | sales@victory-pharm.com | China | 1298 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +86-17732866630 | mina@chuanghaibio.com | China | 18112 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; +86-85511178 | peter68@ptchemgroup.com | China | 35405 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11674 | 58 |
View Lastest Price from 3-(4-IODOPHENYL)PROPIONIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2021-08-12 | 3-(4-IODOPHENYL)PROPIONIC ACID
1643-29-4
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
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2019-12-20 | 3-(4-IODOPHENYL)PROPIONIC ACID
1643-29-4
|
$1.00 | 1KG | 99% | 100kg | Career Henan Chemical Co |
-

- 3-(4-IODOPHENYL)PROPIONIC ACID
1643-29-4
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-

- 3-(4-IODOPHENYL)PROPIONIC ACID
1643-29-4
- $1.00
- 99%
- Career Henan Chemical Co
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