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3-(4-IODOPHENYL)PROPIONIC ACID

CAS No.
1643-29-4
Chemical Name:
3-(4-IODOPHENYL)PROPIONIC ACID
Synonyms
3-(4-IODOPHENYL)PROPANOIC ACID;4-Iodohydrocinnamic acid;3-(4-Iodphenyl)propionsSre;4-Iodo-benzenepropanoic acid;3-(4-Iodphenyl)propionicacid;Benzenepropanoic acid, 4-iodo-;3-(4-IODOPHENYL)PROPIONIC ACID
CBNumber:
CB0433006
Molecular Formula:
C9H9IO2
Molecular Weight:
276.07
MDL Number:
MFCD00017597
MOL File:
1643-29-4.mol
MSDS File:
SDS
Last updated:2026-05-27 22:41:30
Product description Number Pack Size Price
4-Iodo-benzenepropanoic acid 98% AS85340 1g $33
4-Iodo-benzenepropanoic acid 98% AS85340 5g $123
3-(4-Iodophenyl)propanoic acid 98% OR6478 250mg $21
4-Iodo-benzenepropanoic acid 98% AS85340 25g $325
3-(4-Iodophenyl)propanoic acid 98% OR6478 1g $30
More product size

3-(4-IODOPHENYL)PROPIONIC ACID Properties

Melting point 140-142°C
Boiling point 335.4±17.0 °C(Predicted)
Density 1.775±0.06 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
form solid
pka 4.61±0.10(Predicted)
color White to off-white
CAS DataBase Reference 1643-29-4(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Hazard Codes  Xi
HazardClass  IRRITANT
HS Code  2916399090

3-(4-IODOPHENYL)PROPIONIC ACID price More Price(49)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS85340 4-Iodo-benzenepropanoic acid 98% 1643-29-4 1g $33 2026-06-04 Buy
Activate Scientific AS85340 4-Iodo-benzenepropanoic acid 98% 1643-29-4 5g $123 2026-06-04 Buy
Apolloscientific OR6478 3-(4-Iodophenyl)propanoic acid 98% 1643-29-4 250mg $21 2026-06-04 Buy
Activate Scientific AS85340 4-Iodo-benzenepropanoic acid 98% 1643-29-4 25g $325 2026-06-04 Buy
Apolloscientific OR6478 3-(4-Iodophenyl)propanoic acid 98% 1643-29-4 1g $30 2026-06-04 Buy
Product number Packaging Price Buy
AS85340 1g $33 Buy
AS85340 5g $123 Buy
OR6478 250mg $21 Buy
AS85340 25g $325 Buy
OR6478 1g $30 Buy

3-(4-IODOPHENYL)PROPIONIC ACID Chemical Properties,Uses,Production

Uses

p-Iodophenylpropionic acid is a carboxylic acid derivative and can be used as a biochemical reagent.

Synthesis

3-Phenylpropionic acid

501-52-0

3-(4-IODOPHENYL)PROPIONIC ACID

1643-29-4

The general procedure for the synthesis of 3-(4-iodophenyl)propionic acid from hydrogenated cinnamic acid is as follows: 1. Preparation of Intermediate 1: A mixture of H2SO4 (1.25 mL), water (12.5 mL) and AcOH (25 mL) was added to a 250 mL flask. Subsequently 3-phenylpropionic acid (3.00 g, 20.0 mmol), iodine (1.40 g, 5.5 mmol) and KIO3 (0.98 g, 4.6 mmol) were added. 2. the reaction mixture was heated to reflux and a solution of AcOH (25 mL) with iodine (1.40 g, 5.5 mmol) was added in portions, 5 mL at a time. the color of the solution gradually changed from purple to orange during the reaction. 3. After the reaction was carried out for 3 hours, when the color no longer changed, the reaction mixture was cooled to room temperature and the reaction was subsequently quenched with 1 M NaHSO3 solution. 4. Water was added to the reaction mixture and extracted with EtOAc. The organic phases were combined, washed with brine, dried over MgSO4 and concentrated in vacuum. 5. The crude product (4.15 g, 75% yield) containing a small amount of starting material and by-products was recrystallized by petroleum ether to give 1.83 g of pure white crystalline product (33% yield). Rf value: 0.10 (EtOAc:hexane, 1:4); 1H NMR (CDCl3) δ 7.62-7.59 (m, 2H), 6.97-6.95 (m, 2H), 2.92-2.87 (t, 2H, J = 7.5 Hz), 2.68-2.63 (t, 2H, J = 7.5 Hz); 13C NMR (CDCl3) δ 178.5, 139.7, 137.6, 130.4, 91.6, 35.2, 30.0.

References

[1] Patent: WO2010/12650, 2010, A1. Location in patent: Page/Page column 38
[2] Chemistry - A European Journal, 2009, vol. 15, # 10, p. 2278 - 2288
[3] Journal of the American Chemical Society, 2009, vol. 131, # 47, p. 17500 - 17521
[4] European Journal of Organic Chemistry, 2015, vol. 2015, # 27, p. 5919 - 5924
[5] Patent: WO2016/201125, 2016, A1. Location in patent: Page/Page column 19

3-(4-IODOPHENYL)PROPIONIC ACID Preparation Products And Raw materials

Global( 130)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Daken Advanced Materials Co.,Ltd
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PT CHEM GROUP LIMITED
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13417589054 trendseenbio@gmail.com China 11674 58

View Lastest Price from 3-(4-IODOPHENYL)PROPIONIC ACID manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-(4-IODOPHENYL)PROPIONIC ACID pictures 2021-08-12 3-(4-IODOPHENYL)PROPIONIC ACID
1643-29-4
$10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
3-(4-IODOPHENYL)PROPIONIC ACID pictures 2019-12-20 3-(4-IODOPHENYL)PROPIONIC ACID
1643-29-4
$1.00 1KG 99% 100kg Career Henan Chemical Co

3-(4-IODOPHENYL)PROPIONIC ACID Spectrum

3-(4-IODOPHENYL)PROPIONIC ACID 3-(4-Iodphenyl)propionicacid Benzenepropanoic acid, 4-iodo- 3-(4-Iodphenyl)propionsSre 4-Iodohydrocinnamic acid 4-Iodo-benzenepropanoic acid 3-(4-IODOPHENYL)PROPANOIC ACID 1643-29-4 C9HIO2 Aromatic Propionic Acids Carboxylic Acids Phenyls & Phenyl-Het Carboxylic Acids Phenyls & Phenyl-Het Drug Intermediates