3-Phenylpropionic acid
- CAS No.
- 501-52-0
- Chemical Name:
- 3-Phenylpropionic acid
- Synonyms
- HYDROCINNAMIC ACID;3-PHENYLPROPANOIC ACID;BENZENEPROPANOIC ACID;HYDROXYCINNAMIC ACID;Phenylpropanoic acid;Benzenepropionic acid;NSC 9272;LABOTEST-BB LT00014254;3 - styrene acrylic acid;3-Phenyl-n-propionic acid
- CBNumber:
- CB6230832
- Molecular Formula:
- C9H10O2
- Molecular Weight:
- 150.17
- MDL Number:
- MFCD00002771
- MOL File:
- 501-52-0.mol
| Product description | Number | Pack Size | Price |
| 3-Phenylpropionic acid 99%, FG | W288918 | 1 unit | $56.3 |
| 3-Phenylpropionic acid 99%, FG | W288918 | 1 unit | $56.3 |
| 3-Phenylpropionic Acid 99%, FG | W288918 | 100g | $65.26 |
| 3-Phenylpropionic Acid 99%, FG | W288918 | 1kg | $196 |
| 3-Phenylpropionic Acid 99%, FG | W288918 | 10Kg | $1650 |
| More product size | |||
| Melting point | 45-48 °C (lit.) |
|---|---|
| Boiling point | 280 °C (lit.) |
| Density | 1.071 g/mL at 25 °C (lit.) |
| vapor pressure | 0.356Pa at 25℃ |
| refractive index | 1.5408 (estimate) |
| FEMA | 2889 | 3-PHENYLPROPIONIC ACID |
| Flash point | >230 °F |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | 0.6% soluble in water, soluble in alcohol, Propylene glycol, Glycerin and oils |
| form | Liquid |
| pka | 4.66(at 25℃) |
| color | Clear yellow to yellow-green |
| Specific Gravity | 1.071 |
| Odor | Very faint, warm-balsamic and sweet odor of Coumarin-Vanillin-type |
| Odor Type | floral |
| biological source | synthetic |
| Water Solubility | Soluble in water |
| JECFA Number | 646 |
| Merck | 14,4784 |
| BRN | 907515 |
| InChIKey | XMIIGOLPHOKFCH-UHFFFAOYSA-N |
| LogP | 1.153 at 25℃ |
| Substances Added to Food (formerly EAFUS) | 3-PHENYLPROPIONIC ACID |
| CAS DataBase Reference | 501-52-0(CAS DataBase Reference) |
| EWG's Food Scores | 2 |
| FDA UNII | 5Q445IN5CU |
| NIST Chemistry Reference | 3-Phenylpropanoic acid(501-52-0) |
| EPA Substance Registry System | Hydrocinnamic acid (501-52-0) |
| UNSPSC Code | 85151701 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 22-24/25-37/39-26 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | DA8600000 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29163900 | |||||||||
| NFPA 704 |
|
3-Phenylpropionic acid price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | W288918 | 3-Phenylpropionic acid 99%, FG | 501-52-0 | 1 unit | $56.3 | 2025-07-31 | Buy |
| Sigma-Aldrich | W288918 | 3-Phenylpropionic acid 99%, FG | 501-52-0 | 1 unit | $56.3 | 2025-07-31 | Buy |
| Sigma-Aldrich | W288918 | 3-Phenylpropionic Acid 99%, FG | 501-52-0 | 100g | $65.26 | 2025-07-31 | Buy |
| Sigma-Aldrich | W288918 | 3-Phenylpropionic Acid 99%, FG | 501-52-0 | 1kg | $196 | 2025-07-31 | Buy |
| Sigma-Aldrich | W288918 | 3-Phenylpropionic Acid 99%, FG | 501-52-0 | 10Kg | $1650 | 2025-07-31 | Buy |
3-Phenylpropionic acid Chemical Properties,Uses,Production
Description
3-Phenylpropionic acid is a carboxylic acid that belongs to the class of phenylpropanoids. Also referred as hydrocinnamic acid, the chemical is a white crystalline solid with a sweet fatty smell of rose musk cinnamon at room temperature. 3-Phenylpropionic acid is soluble in both water and alcohol. It is widely used in food additives, cosmetics, and pharmaceuticals.
Preparation
Hydrogenation of cinnamic acid is used in the preparation of 3-Phenylpropionic acid. Initially, the chemical was prepared by reduction with sodium amalgam in water by electrolysis.
Uses
Food Industry
3-Phenylpropionic acid is utilized in the food industry as a preservative as well as to maintain the original quality of aroma of frozen foods. It is also used for flavoring and restoring original color to food. 3-Phenylpropionic acid is added to shelved foods to prevent microorganisms from deteriorating the food. It also acts as an antioxidant to prolong the life of foodstuff in shelves. 3-Phenylpropionic acid is also used as a food sweetener.
3-Phenylpropionic acid acts as an emulsifier as it can keep water and oil mixtures separated. 3-Phenylpropionic acid can be added in food for technological reasons in wide range such as processing, manufacturing, packaging, treatment, transportation, and storage.
Cosmetics
3-Phenylpropionic acid is used in beautifying products such as bath gels, detergent powders, and fabric softeners as it gives a floral scent. It is also used as a flavour for mouthwashes and toothpastes.
Chemical Properties
white to off-white crystalline mass, powder or crystals and/or chunk
Chemical Properties
3-Phenylpropionic acid has a faint, sweet odor, somewhat balsamic and coumarin-like with a mildly sweet-sour, vanilla-like taste.
Occurrence
Reported found in raspberry, guava fruit, Vitis vinifera L., papaya, strawberry fruit, cinnamon, cassia leaf, cheddar cheese, cocoa, beer, cognac, white wine, red wine, special wine, rose apple, mushroom, cloudberry, Boletus edulis, fresh mango, licorice and labdanum.
Uses
Used in the compositions for the treatment of blood disorders using α-methylhydrocinnamic acid.
Hydrocinnamic acid was used in the synthesis of three medium-chain acyl-Coenzyme A′s i.e. 3-phenylpropionyl-CoA from mixed anhydrides of fatty acids.
Definition
ChEBI: A monocarboxylic acid that is propionic acid substituted at position 3 by a phenyl group.
Preparation
By reduction of cinnamic acid using sodium amalgam.
Application
3-Phenylpropionic acid is rarely, if ever, used in perfumes, but it finds some use in flavor compositions, mainly as a fixative in Vanilla imitation, in complexes as a sweetener, and in Cheese imitation flavor for its mild pungency and herbaceous character.
Synthesis Reference(s)
Tetrahedron Letters, 29, p. 5599, 1988 DOI: 10.1016/S0040-4039(00)80822-9
General Description
Hydrocinnamic acid forms complexes with uranium(VI) and has been investigated in aqueous solution by attenuated total reflection fourier transform infrared spectroscopy. Hydrocinnamic acids are the major rhizospheric compounds with known growth regulatory activity.
Purification Methods
Crystallise the acid from *benzene, CHCl3 or pet ether (b 40-60o). Dry it in a vacuum. [Beilstein 9 H 508.]
3-Phenylpropionic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8617732866630 | abby@chuanghaibio.com | China | 8772 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5251 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20183 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3692 | 58 |
| JINING XINHE CHEMICAL CO., LTD | +8615318402391 | sales@xinhepharma.com | China | 809 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29734 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21620 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1803 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29852 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10406 | 58 |
View Lastest Price from 3-Phenylpropionic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-10-13 | Hydrocinnamic acid
501-52-0
|
US $31.00 / g | 99.97% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-10-11 | 3-Phenylpropionic acid
501-52-0
|
US $1.00 / KG | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-09-25 | Dapoxetine impurity 28
501-52-0
|
US $0.00-0.00 / mg | 10mg | 0.98 | 10g | ShenZhen H&D Pharmaceutical Technology Co., LTD |
-
- Hydrocinnamic acid
501-52-0
- US $31.00 / g
- 99.97%
- TargetMol Chemicals Inc.
-
- 3-Phenylpropionic acid
501-52-0
- US $1.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- Dapoxetine impurity 28
501-52-0
- US $0.00-0.00 / mg
- 0.98
- ShenZhen H&D Pharmaceutical Technology Co., LTD
