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5,7-Dihydroxycoumarin

CAS No.
2732-18-5
Chemical Name:
5,7-Dihydroxycoumarin
Synonyms
5,7-Dihydroxycoumarin;5,7-dihydroxychromen-2-one;5,7-Dihydroxy-2H-chromen-2-one;5,7-dihydroxy-1-benzopyran-2-one;5,7-Dihydroxy-2H-1-benzopyran-2-one;5,7-Dihydroxycoumarin, 10 mM in DMSO;2H-1-Benzopyran-2-one, 5,7-dihydroxy-;Inhibitor,5,7-Dihydroxycoumarin,antibacterial,Bacterial,inhibit,5,7Dihydroxycoumarin,5,7 Dihydroxycoumarin,coumarin
CBNumber:
CB0446015
Molecular Formula:
C9H6O4
Molecular Weight:
178.14
MDL Number:
MFCD00488354
MOL File:
2732-18-5.mol
MSDS File:
SDS
Last updated:2026-09-12 18:48:20

5,7-Dihydroxycoumarin Properties

Melting point 280 °C
Boiling point 506.4±19.0 °C(Predicted)
Density 1.563±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form Solid
pka 7.18±0.20(Predicted)
color Off-white to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
HS Code  2932990090

5,7-Dihydroxycoumarin price More Price(52)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth FD144414 5,7-Dihydroxycoumarin 2732-18-5 500mg $150 2026-06-04 Buy
Biosynth FD144414 5,7-Dihydroxycoumarin 2732-18-5 250mg $150 2026-06-04 Buy
Biosynth FD144414 5,7-Dihydroxycoumarin 2732-18-5 1000mg $170 2026-06-04 Buy
Biosynth FD144414 5,7-Dihydroxycoumarin 2732-18-5 2000mg $280 2026-06-04 Buy
Biosynth FD144414 5,7-Dihydroxycoumarin 2732-18-5 5000mg $400 2026-06-04 Buy
Product number Packaging Price Buy
FD144414 500mg $150 Buy
FD144414 250mg $150 Buy
FD144414 1000mg $170 Buy
FD144414 2000mg $280 Buy
FD144414 5000mg $400 Buy

5,7-Dihydroxycoumarin Chemical Properties,Uses,Production

Uses

5,7-Dihydroxy-2H-chromen-2-one can be used to prepare UV-responsive coumarin controlled release and self-repairing antifouling paint.

Synthesis Reference(s)

Journal of Medicinal Chemistry, 41, p. 4542, 1998 DOI: 10.1021/jm981032o
Journal of Heterocyclic Chemistry, 2, p. 91, 1965 DOI: 10.1002/jhet.5570020116

Synthesis

Phloroglucinol

108-73-6

Propiolic Acid

471-25-0

5,7-DIHYDROXYCOUMARIN

2732-18-5

The general procedure for the synthesis of 5,7-dihydroxy-2H-benzopyran-2-one from resorcinol and propargyl acid was as follows: a mixture of resorcinol (1.0 mmol), propargyl acid (1.1 mmol), and Yb(OTf)3 hydrate (0.1 mmol) was placed in an open reaction vessel in a microwave reaction unit and irradiated for 2 min at 200 W (80 °C) . The reaction process was monitored by thin layer chromatography (TLC) and the eluent was CH2Cl2/MeOH (99:1). Upon completion of the reaction, the crude product was diluted with ether (Et2O) and the suspension formed was filtered under vacuum to isolate the catalyst and the precipitate was washed with ether several times. The filtrate was washed twice sequentially with 5% NaHCO3 solution (10 mL), dried over anhydrous MgSO4 and evaporated to dryness under vacuum to afford the target product 5,7-dihydroxy-2H-benzopyran-2-one.

References

[1] Synlett, 1999, # 5, p. 608 - 610
[2] Tetrahedron Letters, 2016, vol. 57, # 26, p. 2939 - 2942
[3] Synthesis, 2011, # 8, p. 1283 - 1289
[4] Journal of Natural Medicines, 2017, vol. 71, # 4, p. 735 - 744

487-70-7
2732-18-5
Synthesis of 5,7-Dihydroxycoumarin from 2,4,6-Trihydroxybenzaldehyde
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View Lastest Price from 5,7-Dihydroxycoumarin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5,7-Dihydroxycoumarin pictures 2026-07-14 5,7-Dihydroxycoumarin
2732-18-5
$29.00 98.76% 10g TargetMol Chemicals Inc.
5,7-DIHYDROXYCOUMARIN pictures 2020-01-09 5,7-DIHYDROXYCOUMARIN
2732-18-5
$1.00 1g ≥98% Career Henan Chemical Co
2H-1-Benzopyran-2-one, 5,7-dihydroxy- 5,7-Dihydroxy-2H-1-benzopyran-2-one 5,7-Dihydroxy-2H-chromen-2-one 5,7-dihydroxy-1-benzopyran-2-one 5,7-dihydroxychromen-2-one Inhibitor,5,7-Dihydroxycoumarin,antibacterial,Bacterial,inhibit,5,7Dihydroxycoumarin,5,7 Dihydroxycoumarin,coumarin 5,7-Dihydroxycoumarin, 10 mM in DMSO 5,7-Dihydroxycoumarin 2732-18-5