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6-Methylpyridazin-3(2H)-one

6-Methylpyridazin-3(2H)-one structure

CAS No.: 13327-27-0

Chemical Name:: 6-Methylpyridazin-3(2H)-one

Synonyms: 6-METHYL-3(2H)-PYRIDAZINONE;6Me3OxoPyridaz;SPECS AC-907/25005370;6-Methyl-3-pyridazone;6-Methyl-3-pyridazinone;6-Methylpyridazin-3-one;3-pyridazinol, 6-methyl-;3-methyl-1H-pyridazin-6-one;6-METHYL-2H-PYRIDAZIN-3-ONE;6-METHYLPYRIDAZIN-3[2H]-ONE

CBNumber:: CB0463313

Molecular Formula:: C5H6N2O

Molecular Weight:: 110.11

MDL Number:: MFCD00039720

MOL File:: 13327-27-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-27 22:41:22

Product description	Number	Pack Size	Price
6-Methyl-3(2H)-pyridazinone >98.0%(GC)	M2344	1g	$16
6-Methyl-3(2H)-pyridazinone >98.0%(GC)	M2344	5g	$48
6-Methyl-3(2H)-pyridazinone ≥98%(GC)	43669	1G	$20.43
6-Methyl-3(2H)-pyridazinone ≥98%(GC)	43669	5G	$69.2
6-Methyl-2,3-dihydropyridazin-3-one	134775	1.00g	$101
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6-Methylpyridazin-3(2H)-one Properties

Melting point	143-145°C
Density	1.22±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
pka	11.51±0.40(Predicted)
form	powder to crystal
color	Light yellow to Amber to Dark green
BRN	109928
InChI	InChI=1S/C5H6N2O/c1-4-2-3-5(8)7-6-4/h2-3H,1H3,(H,7,8)
InChIKey	QZWIXLPWMGHDDD-UHFFFAOYSA-N
SMILES	C1(=O)NN=C(C)C=C1
CAS DataBase Reference	13327-27-0(CAS DataBase Reference)
UNSPSC Code	12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P280a-P304+P340-P305+P351+P338-P405-P501a

Hazard Codes

Risk Statements

22-36/37/38

Safety Statements

22-24/25-37-26

WGK Germany

WGK 3

HazardClass

IRRITANT

HS Code

29339900

Storage Class

11 - Combustible Solids

NFPA 704

	1
2		0

6-Methylpyridazin-3(2H)-one price More Price(45)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	M2344	6-Methyl-3(2H)-pyridazinone >98.0%(GC)	13327-27-0	1g	$16	2023-06-20	Buy
TCI Chemical	M2344	6-Methyl-3(2H)-pyridazinone >98.0%(GC)	13327-27-0	5g	$48	2023-06-20	Buy
Chem-Impex	43669	6-Methyl-3(2H)-pyridazinone ≥98%(GC)	13327-27-0	1G	$20.43	2026-05-19	Buy
Chem-Impex	43669	6-Methyl-3(2H)-pyridazinone ≥98%(GC)	13327-27-0	5G	$69.2	2026-05-19	Buy
Matrix Scientific	134775	6-Methyl-2,3-dihydropyridazin-3-one	13327-27-0	1.00g	$101	2026-05-18	Buy

Product number	Packaging	Price	Buy
M2344	1g	$16	Buy
M2344	5g	$48	Buy
43669	1G	$20.43	Buy
43669	5G	$69.2	Buy
134775	1.00g	$101	Buy

6-Methylpyridazin-3(2H)-one Chemical Properties,Uses,Production

Uses

6-Methylpyridazin-3(2H)-one is a lignin-based dye used on wool. It is also used as a reactant for the synthesis of C-(1-aryl-cyclohexyl)-methylamine derivatives as selective, orally available inhibitors of dipeptidyl peptidase IV, imidazopyridazinone derivatives as PDE7 inhibitors and pyridazinone derivatives with an arylpiperazinylalkyl chain as a potentent, orally active, antinociceptive agent.

Definition

ChEBI: 6-Methylpyridazin-3(2H)-one is a member of pyridazines.

Synthesis Reference(s)

Synthesis, p. 1158, 1994 DOI: 10.1055/s-1994-25663

Synthesis

5157-08-4

13327-27-0

General procedure for the synthesis of 6-methyl-3(2H)-pyridazinone from 4,5-dihydro-6-methylpyridazin-3(2H)-one: bromine (7.68 g, 48.05 mmol) was added slowly and dropwise to a solution of 6-methyl-4,5-dihydropyridazin-3(2H)-one (9.0 g, 80.26 mmol) in acetic acid (90 mL) at 90 °C. The reaction mixture was stirred continuously at 90 °C for 5-6 hours. Upon completion of the reaction, the excess acetic acid was removed by distillation under reduced pressure. The resulting residue was neutralized with aqueous sodium bicarbonate solution, followed by filtration to collect the solid product. The filter cake was dried to give the title compound 6-methyl-3(2H)-pyridazinone (6.0 g, 68% yield). The structure of the product was confirmed by 1H NMR (300 MHz, DMSO-d6): δ 12.73 (s, 1H), 7.30 (d, J = 9.6 Hz, 1H), 6.80 (d, J = 9.9 Hz, 1H), 2.14 (s, 3H).

References

[1] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 19, p. 6286 - 6291
[2] Journal of Chemical Research, Miniprint, 1995, # 8, p. 1840 - 1852
[3] Journal of the Chemical Society, 1947, p. 239,242
[4] Patent: US4595521, 1986, A

6-Methylpyridazin-3(2H)-one Preparation Products And Raw materials

Raw materials

4,5-Dihydro-6-methylpyridazin-3(2H)-one Furfuryl alcohol

Preparation Products

3-bromo-6-methylpyridazine 6-Chloro-pyridazine-3-carboxylic acid ethyl ester 3-MERCAPTO-6-METHYLPYRIDAZINE

6-Methylpyridazin-3(2H)-one Suppliers

Global( 247)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hangzhou Lucky Biology Co., Ltd	+8618105713381	lucky@lkbiology.com	China	174	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Springchem New Material Technology Co.,Limited	+86-021-62885108 +8613917661608	info@spring-chem.com	China	2068	57
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4241	58
Xiamen AmoyChem Co., Ltd	+86-86-5926051114 +8615060885618	sales@amoychem.com	China	6366	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17346	58

Supplier	Advantage
Hangzhou Lucky Biology Co., Ltd	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Springchem New Material Technology Co.,Limited	57
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Changzhou Ansciep Chemical Co., Ltd.	58
Xiamen AmoyChem Co., Ltd	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
SIMAGCHEM CORP	58

View Lastest Price from 6-Methylpyridazin-3(2H)-one manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-03-20	6-Methylpyridazin-3(2H)-one 13327-27-0	$10.00	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd
2025-11-18	6-Methylpyridazin-3(2H)-one 13327-27-0	$1.10	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
2025-04-04	6-Methylpyridazin-3(2H)-one 13327-27-0		1KG	98%	1ton	Henan Aochuang Chemical Co.,Ltd.

6-Methylpyridazin-3(2H)-one
13327-27-0
$10.00
99%
Hebei Chuanghai Biotechnology Co., Ltd

6-Methylpyridazin-3(2H)-one
13327-27-0
$1.10
99.00%
Dideu Industries Group Limited

6-Methylpyridazin-3(2H)-one
13327-27-0
98%
Henan Aochuang Chemical Co.,Ltd.

6-Methylpyridazin-3(2H)-one Spectrum

6-Methylpyridazin-3(2H)-one(13327-27-0)MS 6-Methylpyridazin-3(2H)-one(13327-27-0)¹HNMR 6-Methylpyridazin-3(2H)-one(13327-27-0)IR1 6-Methylpyridazin-3(2H)-one(13327-27-0)IR2

13327-27-0(6-Methylpyridazin-3(2H)-one)Related Search:

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6-Methyl-2,3-dihydropyridazine-3-one 3-pyridazinol, 6-methyl- 3-methyl-1H-pyridazin-6-one 6-Methyl-2H-pyridazin-3-o... 3-Hydroxy-6-methylpyridazine 6-Methylpyridazine-3[2H]-one 6-Methyl-1,2-dihydropyriMidin-2-one 6-Methyl-3-pyridazinone 6-Methyl-2H-pyridazine-3-one hydrobrMide salt 4-ChlorothiobenzaMide, 97%, 97% 6-Methyl-3(2H)-pyridazinone,98% 6Me3OxoPyridaz 6-Methyl-3(2H)-pyridazinone SPECS AC-907/25005370 6-METHYL-2H-PYRIDAZIN-3-ONE 6-METHYLPYRIDAZIN-3[2H]-ONE 3(2H)-Pyridazinone,6-methyl- 6-METHYL-2,3-DIHYDROPYRIDAZIN-3-ONE 6-Methylpyridazin-3-one 6-Methylpyridazin-32Hü-one, 98% 6-Methyl-3-pyridazone 3-Hydroxy-6-methylpyridazine 97% 6-Methyl-3(2H)-pyridazinone> 6-Methylpyridazin-3(2H)-one ISO 9001：2015 REACH 6-Methyl-3-pyridazinone-98% 6-methyl-3 (2H) - pyridazine ketone 6-METHYL-3(2H)-PYRIDAZINONE 13327-27-0