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PF-4363467

PF-4363467 Structure
PF-4363467 structure
CAS No.
2040055-84-1
Chemical Name:
PF-4363467
Synonyms
PF-4363467;PF 04363467;Benzenesulfonamide, N-[4-[(2R)-4-ethyl-2-morpholinyl]-2-methylphenyl]-4-(1-methylethyl)-
CBNumber:
CB04668376
Molecular Formula:
C22H30N2O3S
Molecular Weight:
402.55
MDL Number:
MOL File:
2040055-84-1.mol
Last updated:2025-04-18 09:51:29
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PF-4363467 Properties

Boiling point 523.8±60.0 °C(Predicted)
Density 1.164±0.06 g/cm3(Predicted)
pka 8.79±0.10(Predicted)

PF-4363467 Chemical Properties, Uses, Production

Uses

PF-4363467, a dopamine D3/D2 receptor antagonist, attenuates opioid drug-seeking behavior without concomitant D2 side effects. PF-4363467 exhibits Ki values of 3.1 nM and 692 nM for D3R and D2R[1].

IC 50

D3 Receptor: 3.1 nM (Ki); D2 Receptor: 692 nM (Ki)

References

[1] Dopamine D3/D2 Receptor Antagonist PF-4363467 Attenuates Opioid Drug-Seeking Behavior without Concomitant D2 Side Effects. ACS Chem Neurosci. 2017 Jan 18;8(1):165-177. DOI:10.1021/acschemneuro.6b00297

PF-4363467 Preparation Products And Raw materials

Raw materials

Preparation Products

PF-4363467 Suppliers

Global Suppliers ( 2)
Supplier Tel Email Country ProdList Advantage
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd 15317229551 15151849396@163.com China 975 58
TargetMol 400-821-0310 15002144251 xuexiang.shao@tsbiochem.com China 29128 58
Supplier Advantage
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd 58
TargetMol 58

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PF-4363467 PF 04363467 Benzenesulfonamide, N-[4-[(2R)-4-ethyl-2-morpholinyl]-2-methylphenyl]-4-(1-methylethyl)- 2040055-84-1