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PKCiota-IN-49

PKCiota-IN-49 Structure
PKCiota-IN-49 structure
CAS No.
2230055-52-2
Chemical Name:
PKCiota-IN-49
Synonyms
PKCiota-IN-2;PKCiota-IN-49;PKCiota-IN-2, 10 mM in DMSO;6-methoxy-7-(5-{1H-pyrrolo[2,3-b]pyridin-4-yl}pyrazolo[1,5-a]pyridin-3-yl)-1,2,3,4-tetrahydroisoquinoline;Isoquinoline, 1,2,3,4-tetrahydro-6-methoxy-7-[5-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrazolo[1,5-a]pyridin-3-yl]-
CBNumber:
CB04668396
Molecular Formula:
C24H21N5O
Molecular Weight:
395.46
MDL Number:
MOL File:
2230055-52-2.mol
MSDS File:
SDS
Last updated:2026-07-14 16:49:18
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PKCiota-IN-49 Properties

Density 1.39±0.1 g/cm3(Predicted)
pka 12.44±0.40(Predicted)

PKCiota-IN-49 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
aablocks AA027HXN PKCiota-IN-2 2230055-52-2 1mg $114 2026-06-02 Buy
aablocks AA027HXN PKCiota-IN-2 2230055-52-2 2mg $160 2026-06-02 Buy
aablocks AA027HXN PKCiota-IN-2 2230055-52-2 5mg $236 2026-06-02 Buy
aablocks AA027HXN PKCiota-IN-2 2230055-52-2 10mg $336 2026-06-02 Buy
aablocks AA027HXN PKCiota-IN-2 2230055-52-2 25mg $494 2026-06-02 Buy
Product number Packaging Price Buy
AA027HXN 1mg $114 Buy
AA027HXN 2mg $160 Buy
AA027HXN 5mg $236 Buy
AA027HXN 10mg $336 Buy
AA027HXN 25mg $494 Buy

PKCiota-IN-49 Chemical Properties, Uses, Production

Uses

PKCiota-IN-2 (Compound 49) is a potent PKCiota (PKC-ι) inhibitor with an IC50 of 2.8 nM. PKCiota-IN-2 also inhibits PKC-α and PKC-ε with IC50s of 71 nM and 350 nM, respectively[1].

IC 50

PKCι: 2.8 nM (IC50); PKCα: 71 nM (IC50); PKCε: 350 nM (IC50)

References

[1] Jacek Kwiatkowski, et al. Fragment-Based Drug Discovery of Potent Protein Kinase C Iota Inhibitors. J Med Chem. 2018 May 24;61(10):4386-4396. DOI:10.1021/acs.jmedchem.8b00060

PKCiota-IN-49 Preparation Products And Raw materials

Raw materials

Preparation Products

PKCiota-IN-49 Suppliers

Global Suppliers ( 14)
Supplier Tel Email Country ProdList Advantage
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4860 55
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8000 62
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd 15317229551 15151849396@163.com China 959 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
https://hanhongsci.com/ 021-54306202 18917919676 info@hanhongsci.com China 29982 58
Beijing Boorsen Biotechnology Co., Ltd 400-901-9800 18611424007 cis@bioss.com.cn China 9185 58
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 cindy.huang@synzest.com China 11975 58
Ningbo Chaoming Biotechnology Co., Ltd 13301662590 mandy@atkchemical.com China 9539 58
Supplier Advantage
Shanghai Lollane Biological Technology Co.,Ltd. 55
ShangHai Biochempartner Co.,Ltd 62
TargetMol Chemicals Inc. 58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd 58
TargetMol Chemicals Inc. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
https://hanhongsci.com/ 58
Beijing Boorsen Biotechnology Co., Ltd 58
Nanjing Shizhou Biology Technology Co.,Ltd 58
Ningbo Chaoming Biotechnology Co., Ltd 58

View Latest Price from PKCiota-IN-49 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PKCiota-IN-2 pictures 2026-07-14 PKCiota-IN-2
2230055-52-2
 $117.00-269.00 99.74% 10g TargetMol Chemicals Inc.
  • PKCiota-IN-2 pictures
  • PKCiota-IN-2
    2230055-52-2
  • $117.00-269.00
  • 99.74%
  • TargetMol Chemicals Inc.

PKCiota-IN-49 Spectrum

PKCiota-IN-49(2230055-52-2)1HNMR

2230055-52-2 (PKCiota-IN-49) Related Search:

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Verbascoside

1of2

PKCiota-IN-49 PKCiota-IN-2 Isoquinoline, 1,2,3,4-tetrahydro-6-methoxy-7-[5-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrazolo[1,5-a]pyridin-3-yl]- 6-methoxy-7-(5-{1H-pyrrolo[2,3-b]pyridin-4-yl}pyrazolo[1,5-a]pyridin-3-yl)-1,2,3,4-tetrahydroisoquinoline PKCiota-IN-2, 10 mM in DMSO 2230055-52-2