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7-CHLORO-4-QUINAZOLINOL

7-CHLORO-4-QUINAZOLINOL structure

CAS No.: 31374-18-2

Chemical Name:: 7-CHLORO-4-QUINAZOLINOL

Synonyms: Compound Fr12428;7-CHLORO-4-QUINAZOLINOL;7-CHLOROQUINAZOLIN-4-OL;7-Chloroquinazolin-4-one;7-Chloro-4(3H)-quinazolone;7-Chloro-3H-quizolin-4-one;7-CHOROQUINAZOLIN-4(3H)-ONE;7-Chloroquinazolin-4(1H)-one;7-chloro-1H-quinazolin-4-one;7-Chloroquinazolin-4(3H)-one

CBNumber:: CB0470643

Molecular Formula:: C8H5ClN2O

Molecular Weight:: 180.59

MDL Number:: MFCD00115130

MOL File:: 31374-18-2.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:50

Product description	Number	Pack Size	Price
7-Chloroquinazolin-4(1H)-one min. 98.0 %	C3720	1G	$40
7-Chloroquinazolin-4(1H)-one min. 98.0 %	C3720	5G	$121
7-Chloro-4-hydroxyquinazoline	C381203	50mg	$60
7-Chloro-4-hydroxyquinazoline 95+%	073870	10g	$69
7-Chloro-4-hydroxyquinazoline	W5341	1g	$70
More product size

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7-CHLORO-4-QUINAZOLINOL Properties

Melting point	251-253 °C
Boiling point	331.7±44.0 °C(Predicted)
Density	1.50±0.1 g/cm3(Predicted)
storage temp.	Inert atmosphere,Room Temperature
pka	0.36±0.20(Predicted)
Appearance	Off-white to light brown Solid
InChI	InChI=1S/C8H5ClN2O/c9-5-1-2-6-7(3-5)10-4-11-8(6)12/h1-4H,(H,10,11,12)
InChIKey	PMLONMIODRHERC-UHFFFAOYSA-N
SMILES	N1C2=C(C=CC(Cl)=C2)C(=O)NC=1

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H332-H335
Precautionary statements	P261-P280-P305+P351+P338
HS Code	2933998090

7-CHLORO-4-QUINAZOLINOL price More Price(21)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	C3720	7-Chloroquinazolin-4(1H)-one min. 98.0 %	31374-18-2	1G	$40	2025-07-31	Buy
TCI Chemical	C3720	7-Chloroquinazolin-4(1H)-one min. 98.0 %	31374-18-2	5G	$121	2025-07-31	Buy
TRC	C381203	7-Chloro-4-hydroxyquinazoline	31374-18-2	50mg	$60	2021-12-16	Buy
Matrix Scientific	073870	7-Chloro-4-hydroxyquinazoline 95+%	31374-18-2	10g	$69	2021-12-16	Buy
AK Scientific	W5341	7-Chloro-4-hydroxyquinazoline	31374-18-2	1g	$70	2021-12-16	Buy

Product number	Packaging	Price	Buy
C3720	1G	$40	Buy
C3720	5G	$121	Buy
C381203	50mg	$60	Buy
073870	10g	$69	Buy
W5341	1g	$70	Buy

7-CHLORO-4-QUINAZOLINOL Chemical Properties,Uses,Production

Synthesis Reference(s)

Journal of the American Chemical Society, 68, p. 1305, 1946 DOI: 10.1021/ja01211a058

Synthesis

3473-63-0

89-77-0

31374-18-2

The general procedure for the synthesis of 7-chloro-4(3H)-quinazolinone from formamidine acetate and 2-amino-4-chlorobenzoic acid was as follows: 10 g of 2-amino-4-chlorobenzoic acid (BB1) and 8 g of formamidine acetate (1.3 eq.) were added to a 100 ml eggplant flask and mixed thoroughly. The mixture was placed in a microwave reactor and reacted at 60% power for 4 min. After completion of the reaction, it was cooled to room temperature, 30 ml of water was added, stirred and the solid product was collected by filtration. The resulting product was 7-chloro-4(3H)-quinazolinone (BB2) in a yield of 10 g with 95% yield.

References

[1] Patent: CN103570738, 2016, B. Location in patent: Paragraph 0303; 0304; 0306
[2] Patent: CN103382182, 2016, B. Location in patent: Paragraph 0272-0275
[3] Patent: WO2012/88712, 2012, A1. Location in patent: Page/Page column 16
[4] MedChemComm, 2015, vol. 6, # 1, p. 222 - 229

7-CHLORO-4-QUINAZOLINOL synthesis

Synthesis of 7-CHLORO-4-QUINAZOLINOL from Formamidine acetate and 2-Amino-4-chlorobenzoic acid

7-CHLORO-4-QUINAZOLINOL Preparation Products And Raw materials

Raw materials

Formamide, acetate (1:1) Benzamide, 4-chloro-2-iodo- formamidine 2-Amino-4-chlorobenzoic acid Methanol

formamide 2-AMINO-4-CHLOROBENZOIC ACID 7-chloroquinazoline-2,4(1H,3H)-dione 2-Amino-4-chlorobenzonitrile 2-amino-4-chlorobenzamide

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Preparation Products

USP7-IN-1 N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-aminoquinazolin-4-aMine 4,7-Dichloroquinazoline

7-CHLORO-4-QUINAZOLINOL Suppliers

Global( 172)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shaanxi Dideu Medichem Co. Ltd	+86-029-81138252 +86-173 9270 1263	1057@dideu.com	China	3998	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Anqing Chico Pharmaceutical Co., Ltd.	15380796838	chloewu@chicopharm.cn	CHINA	340	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29833	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Shanghai Yingrui Biopharma Co.,Ltd	21-33585366	export01@shyrchem.com	CHINA	1319	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	9948	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Shanghai Yudiao Chemistry Technology Co.,Ltd	02137285211 18964703211	info@yudiaochem.com	CHINA	238	58

Supplier	Advantage
Shaanxi Dideu Medichem Co. Ltd	58
Capot Chemical Co.,Ltd.	60
Anqing Chico Pharmaceutical Co., Ltd.	58
career henan chemical co	58
Alchem Pharmtech,Inc.	58
Shanghai Yingrui Biopharma Co.,Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Fuxin Pharmaceutical	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Shanghai Yudiao Chemistry Technology Co.,Ltd	58

View Lastest Price from 7-CHLORO-4-QUINAZOLINOL manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-07-21	7-CHLORO-4-QUINAZOLINOL 31374-18-2	US $1.00 / Kg	1Kg	98%	20T	Shaanxi Dideu Medichem Co. Ltd
	2019-07-06	7-CHLORO-4-QUINAZOLINOL 31374-18-2	US $100.00 / KG	1KG	98%	200KG	Career Henan Chemical Co

7-CHLORO-4-QUINAZOLINOL
31374-18-2
US $1.00 / Kg
98%
Shaanxi Dideu Medichem Co. Ltd

7-CHLORO-4-QUINAZOLINOL
31374-18-2
US $100.00 / KG
98%
Career Henan Chemical Co

7-CHLORO-4-QUINAZOLINOL Spectrum

7-CHLORO-4-QUINAZOLINOL(31374-18-2)¹HNMR

31374-18-2(7-CHLORO-4-QUINAZOLINOL)Related Search:

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7-CHLOROQUINAZOLIN-4-OL 7-CHLORO-4(1H)-QUINAZOLINONE 7-CHLORO-4-QUINAZOLINOL 7-CHLORO-4-HYDROXYQUINAZOLINE 7-Chloro-4(3H)-quinazolone 7-Chloroquinazolin-4(3H)-one 7-Chloroquinazolin-4-one 7-chloro-1H-quinazolin-4-one 4(3H)-Quinazolinone, 7-chloro- 7-Chloroquinazolin-4(1H)-one 7-Chloro-4(3H-quinazolin-4-one 7-Chloro-3H-quinazolin-4-one 7-chloro-4(3H)-quinazolinone 7-CHLORO-4-QUINAZOLINOL###31374-18-2 7-Chloro-4-Hydroxyquinazoline(WX636185) 7-Chloro-3H-quizolin-4-one 7-chloro-1,4-dihydroquinazolin-4-one 7-CHOROQUINAZOLIN-4(3H)-ONE Cyclopropanamine,1-ethyl-,hydrochloride(1:5) Benzenesulfonylchloride,9-ethoxy- Compound Fr12428 31374-18-2 128517-87-2 Alcohols and Derivatives Heterocycles