Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>6-Chloro-4-hydroxyquinazoline

6-Chloro-4-hydroxyquinazoline

6-Chloro-4-hydroxyquinazoline Structure
6-Chloro-4-hydroxyquinazoline structure
CAS No.
16064-14-5
Chemical Name:
6-Chloro-4-hydroxyquinazoline
Synonyms
6-chloroquinazolin-4(1H)-one;6-CHLOROQUINAZOLIN-4-OL;6-CHLOROQUINAZOLIN-4(3H)-ONE;6-CHLORO-4-QUINAZOLONE;6-CHLORO-4-QUINAZOLINONE;6-chloro-4(3h)-quinazolinon;6-chlro-4-hydroxyquinazoline;6-CHLORO-3H-QUINAZOLIN-4-ONE;6-CHLORO-4(3H)-QUINAZOLINONE;6-CHLORO-4-HYDROXYQUINAZOLINE
CBNumber:
CB3137947
Molecular Formula:
C8H5ClN2O
Molecular Weight:
180.59
MDL Number:
MFCD01686365
MOL File:
16064-14-5.mol
MSDS File:
SDS
Last updated:2026-05-28 00:57:12
Request For Quotation

6-Chloro-4-hydroxyquinazoline Properties

Melting point 263-265 °C
Boiling point 128.9°C (rough estimate)
Density 1.4300 (rough estimate)
refractive index 1.5430 (estimate)
storage temp. Sealed in dry,Room Temperature
pka 0.93±0.20(Predicted)
Appearance Off-white to light brown Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P280-P305+P351+P338-P310
Hazard Codes  Xi
Hazard Note  Irritant
HS Code  2933599590

6-Chloro-4-hydroxyquinazoline price More Price(51)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich R745979 6-CHLORO-4(3H)-QUINAZOLINONE AldrichCPR 16064-14-5 1 unit $121 2026-04-30 Buy
Sigma-Aldrich R745979 6-CHLORO-4(3H)-QUINAZOLINONE AldrichCPR 16064-14-5 25MG $106 2023-06-20 Buy
Apolloscientific OR8300 6-Chloroquinazolin-4(3H)-one >97% 16064-14-5 5g $21 2026-06-04 Buy
Apolloscientific OR8300 6-Chloroquinazolin-4(3H)-one >97% 16064-14-5 25g $37 2026-06-04 Buy
Apolloscientific OR8300 6-Chloroquinazolin-4(3H)-one >97% 16064-14-5 100g $135 2026-06-04 Buy
Product number Packaging Price Buy
R745979 1 unit $121 Buy
R745979 25MG $106 Buy
OR8300 5g $21 Buy
OR8300 25g $37 Buy
OR8300 100g $135 Buy

6-Chloro-4-hydroxyquinazoline Chemical Properties, Uses, Production

Synthesis

formamide

77287-34-4

2-Amino-5-chlorobenzamide

5202-85-7

6-Chloro-4-hydroxyquinazoline

16064-14-5

Yb(OTf)3 (0.20 mmol, 5.0 mol%) and homotrimethylbenzene (5.0 mL) were added to a 20 mL Pyrex flask equipped with a magnetic stirring bar and a reflux condenser under argon protection, using 2-amino-5-chlorobenzamide (1, 4.0 mmol) and formamide (2, 6.0 mmol). The reaction mixture was stirred at 120-165 °C (bath temperature) for 6 hours. After completion of the reaction, the mixture was cooled to room temperature and analyzed by GLC, GC-MS (EI) and LC-MS (ESI). After removal of homotrimethylbenzene by evaporation under vacuum, the product 6-chloroquinazolin-4-one (3) was separated by recrystallization from MeOH/hexanes and/or silica gel medium pressure column chromatography (eluent: EtOAc/hexanes = 50/50 to 100% EtOAc. for 3j, eluent: MeOH/CHCl3 = 50/50). The structures of the products were confirmed by 1H NMR (400 MHz, DMSO-d6) and 13C NMR (100 MHz, DMSO-d6) spectra. The analytical and spectral data of compounds 3a-e, 3f, 3g, 3h and 3j were in agreement with literature reports. The characterization data of product 3i are given below.

References

[1] Heterocycles, 2015, vol. 90, # 2, p. 857 - 865

6-Chloro-4-hydroxyquinazoline Preparation Products And Raw materials

Raw materials

Methanol Formamidine acetate formamide Methyl 5-chloroanthranilate 2-Amino-5-chlorobenzoic acid
2-Amino-5-chlorobenzamide Mesitylene Ytterbium(III) trifluoromethanesulfonate hydrate

1of2

Preparation Products

6-Chloro-4-hydroxyquinazoline Suppliers

Global Suppliers ( 112)
Supplier Tel Email Country ProdList Advantage
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd. 21-57721279 18121011378 sales@shydchem.com.cn China 998 56
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Shanghai Paulshine Chemical Co., Ltd. +86-021-37788663 China 186 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Chengdu Forest Science and Technology Development Co., Ltd. 18030648795 18030648795 sales@cdforestchem.com China 1998 58
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd. +86-28-85122536 85324413 market@astatech.cn China 8016 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Supplier Advantage
Wuhan Chemwish Technology Co., Ltd 56
Beijing Ouhe Technology Co., Ltd 60
Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd. 56
Adamas Reagent, Ltd. 59
Shanghai Paulshine Chemical Co., Ltd. 64
Shanghai Hanhong Scientific Co.,Ltd. 64
Shandong Xiya Chemical Co., Ltd 57
Chengdu Forest Science and Technology Development Co., Ltd. 58
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd. 55
Bide Pharmatech Ltd. 60

View Latest Price from 6-Chloro-4-hydroxyquinazoline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
6-Chloro-4-hydroxyquinazoline pictures 2026-08-20 6-Chloro-4-hydroxyquinazoline
16064-14-5
 $1.10 1g 99.00% 100 Tons Dideu Industries Group Limited
6-Chloro-4-hydroxyquinazoline pictures 2019-07-10 6-Chloro-4-hydroxyquinazoline
16064-14-5
 $8.80 1KG 97%-99% 100kg Career Henan Chemical Co

6-Chloro-4-hydroxyquinazoline Spectrum

6-Chloro-4-hydroxyquinazoline(16064-14-5)1HNMR

16064-14-5 (6-Chloro-4-hydroxyquinazoline) Related Search:

Cefazolin sodium salt Naphazoline hydrochloride Cefazolin Hydroxychloroquine Difluorochloromethane
4-Hydroxyquinazoline Halofuginone Halofuginone Lactate 4-Chloro-6-hydroxyquinazoline 7-Chloro-4-quinazolinol
6-chloro-2-methyl-4(1H)-quinazolinone 6,8-Dichloro-3H-quinazolin-4-one 4-Chloro-7-hydroxyquinazoline 2-Chloro-4-hydroxyquinazoline 6-Nitro-7-Chloro-4-HydroxyQuinazoline
6-chloro-2-mercaptoquinazolin-4(3H)-one 6-Chloro-4-ethoxy-2-methylquinazoline 6-Chloro-4-methoxy-2-methylquinazoline

1of4

6-chloro-4(3h)-quinazolinon 6-CHLOROQUINAZOLIN-4(3H)-ONE 6-CHLORO-4-HYDROXYQUINAZOLINE 6-CHLORO-3H-QUINAZOLIN-4-ONE 6-CHLORO-4-QUINAZOLINONE 6-CHLORO-4-QUINAZOLONE 6-Chloroquinazolin-4-ol, 6-Chloro-4-hydroxyquinazoline 6-Chloroquinazolin-4(3H)-one 98% 6-chlro-4-hydroxyquinazoline 6-Chloro-3-hydroquinazolin-4-one 6-Chloro-3,4-dihydroquinazoline-4-one 6-chloroquinazolin-4(1H)-one 4(3H)-Quinazolinone, 6-chloro- 6-Chloro-4-hydroxyquinazoline ISO 9001：2015 REACH 6-CHLORO-4(3H)-QUINAZOLINONE 6-CHLOROQUINAZOLIN-4-OL 16064-14-5 blocks Heterocycles Quinolines