Purpurin
- CAS No.
- 81-54-9
- Chemical Name:
- Purpurin
- Synonyms
- Verantin;1,2,4-TRIHYDROXYANTHRAQUINONE;CI 58205;c.i.1037;Purpurin;Purpurine;C.I. 1037;c.i.75410;NSC 10447;C.I. 75410
- CBNumber:
- CB0715728
- Molecular Formula:
- C14H8O5
- Molecular Weight:
- 256.21
- MDL Number:
- MFCD00001203
- MOL File:
- 81-54-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 253-256 °C(lit.) |
|---|---|
| Boiling point | 359.45°C (rough estimate) |
| Density | 1.659 |
| refractive index | 1.4825 (estimate) |
| Flash point | 113 °C |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
| pka | 7.05±0.20(Predicted) |
| form | Powder |
| Colour Index | 58205 |
| color | Brown-red to brown |
| Water Solubility | 6.405mg/L(25 ºC) |
| λmax |
515 nm 521 nm (2nd) |
| Merck | 14,7945 |
| BRN | 1887127 |
| Major Application |
diagnostic assay manufacturing hematology histology |
| InChI | 1S/C14H8O5/c15-8-5-9(16)14(19)11-10(8)12(17)6-3-1-2-4-7(6)13(11)18/h1-5,15-16,19H |
| InChIKey | BBNQQADTFFCFGB-UHFFFAOYSA-N |
| SMILES | Oc1cc(O)c2C(=O)c3ccccc3C(=O)c2c1O |
| LogP | 4.600 (est) |
| CAS DataBase Reference | 81-54-9 |
| EWG's Food Scores | 1 |
| FDA UNII | L1GT81LS6N |
| EPA Substance Registry System | Purpurin (81-54-9) |
| UNSPSC Code | 41116107 |
| NACRES | NA.47 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi,C,F | |||||||||
| Risk Statements | 36/37/38-34-11 | |||||||||
| Safety Statements | 26-36-45-36/37/39-16 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | CB8200000 | |||||||||
| HS Code | 29146990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
Purpurin price More Price(52)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHL89771 | Purpurin phyproof? Reference Substance | 81-54-9 | 100MG | $287 | 2026-04-30 | Buy |
| Sigma-Aldrich | 229148 | Purpurin Dye content 90% | 81-54-9 | 5g | $79.6 | 2026-04-30 | Buy |
| TCI Chemical | P0605 | Purpurin >95.0%(HPLC) | 81-54-9 | 25g | $401 | 2026-04-30 | Buy |
| Cayman Chemical | 11752 | Purpurin ≥95% | 81-54-9 | 5g | $36 | 2026-04-30 | Buy |
| Cayman Chemical | 11752 | Purpurin ≥95% | 81-54-9 | 10g | $68 | 2026-04-30 | Buy |
Purpurin Chemical Properties, Uses, Production
Chemical Properties
brown-red to brown powder
Uses
xanthin oxidase inhibitor, irritant
Uses
Purpurin is an anthraquinone derivative and is well known as a colour pigment derived from madder plants. Purpurin was extensively utilized in herbal remedies, in food colouring and dyes for cotton pr inting. Due to the high antioxidant activity exhibited by anthraquinone compounds, purpurin was determined through studies to possess potential radical scavenging effects. Purprin has also been shown to have inhibitory effects towards serine protease.
Uses
A xanthine oxidase inhibitor.
Uses
Purpurin is a naturally occurring reddish-yellow pigment found in madder root (R. tinctorum) that has been used both in herbal remedies and as food coloring. It can also by synthetically derived from 9,10-anthraquinone. Purpurin is protective against a number of food-derived heterocyclic amines in bacterial mutagenicity assays through its inhibition of CYP450-dependent N-hydroxylation and reduction of N-hydroxylamines. Purpurine can also inhibit (IC50 = 6.6 μM) spermidine-induced autoactivation of plasma hyaluronan-binding protein, a serine protease that can activate coagulation factor VII and prourokinase.
Definition
ChEBI: A trihydroxyanthraquinone derived from anthracene by substitution with oxo groups at C-9 and C-10 and with hydroxy groups at C-1, C-2 and C-4.
in vivo
Purpurin (Orally; 2, 6, 18 mg/kg for 3 weeks) exerts dose-dependently antidepressant-like effects on behavior and stress axis reactivity in adult male C57BL/6J mice (6-7 weeks old upon arrival)[1].
Purification Methods
Crystallise purpurin from aqueous EtOH, dry it at 100o. [Beilstein 8 IV 3568.]
Purpurin Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Sichuan Kulinan Technology Co., Ltd | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11674 | 57 |
| Sinopharm Chemical Reagent Co,Ltd. | 86-21-63210123 | sj_scrc@sinopharm.com | China | 9791 | 79 |
| Maya High Purity Chemicals | +86 (573) 82222445 (0)18006601000 452520369 | sales@maya-r.com | China | 11693 | 57 |
| Dalian Meilun Biotech Co., Ltd. | 0411-62910999 13889544652 | sales@meilune.com | China | 4765 | 58 |
View Latest Price from Purpurin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-27 | Purpurin
81-54-9
|
$30.00-93.00 | 96.48% | 10g | TargetMol Chemicals Inc. | ||
 |
2023-02-24 | Purpurin
81-54-9
|
20mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | ||
 |
2019-07-06 | PURPURIN
81-54-9
|
$1.00 | 1g | 99% | 100KG | Career Henan Chemical Co |
