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1-(4-Methoxyphenyl)piperazine dihydrochloride

CAS No.
38869-47-5
Chemical Name:
1-(4-Methoxyphenyl)piperazine dihydrochloride
Synonyms
MeOPP;TIMTEC-BB SBB003069;PMPP DIHYDROCHLORIDE;UrapidilImpurity2piper;1-(4-METHOXYPHENYL) PIPERAZINE 2HCL;1-(4-methoxyphenyl)piperazine DIHCL;N-(4-METHOXYPHENYL) PIPERAZINE 2HCL;1-(4-Methoxyphenyl) Dihydrochloride;1-(P-METHOXYPHENYL)PIPERAZINE DI HCL;MethoxyPhenylPiperazineHydrochloride
CBNumber:
CB0732112
Molecular Formula:
C11H18Cl2N2O
Molecular Weight:
265.18
MDL Number:
MFCD00012767
MOL File:
38869-47-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 22:50:36

1-(4-Methoxyphenyl)piperazine dihydrochloride Properties

Melting point 240 °C (dec.)(lit.)
storage temp. -20°C Freezer
solubility DMF: 5 mg/ml; DMSO: 30 mg/ml; Methanol: 1 mg/ml; PBS (pH 7.2): 10 mg/ml
form powder to crystal
color White to Light yellow to Light red
Water Solubility very faint turbidity
Sensitive Hygroscopic
BRN 4275784
InChI InChI=1S/C11H16N2O.2ClH/c1-14-11-4-2-10(3-5-11)13-8-6-12-7-9-13;;/h2-5,12H,6-9H2,1H3;2*1H
InChIKey MMXANKLJIHSIQH-UHFFFAOYSA-N
SMILES N1(C2=CC=C(OC)C=C2)CCNCC1.[H]Cl.[H]Cl
CAS DataBase Reference 38869-47-5(CAS DataBase Reference)
FDA UNII ARJ7BR8SNG
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)Exclamation Mark (GHS07)
GHS06,GHS07
Signal word  Danger
Hazard statements  H301-H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P501a-P264-P270-P280-P301+P310+P330-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P405-P501
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  28A-26-36-24/25
RIDADR  2811
WGK Germany  3
HazardClass  6.1
PackingGroup  III
HS Code  29349990
Storage Class 11 - Combustible Solids
NFPA 704
1
2 0

1-(4-Methoxyphenyl)piperazine dihydrochloride price More Price(43)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich M23004 1-(4-Methoxyphenyl)piperazine dihydrochloride technical grade, 90% 38869-47-5 25g $147 2026-04-30 Buy
TCI Chemical M1449 1-(4-Methoxyphenyl)piperazine Dihydrochloride >98.0%(HPLC)(T) 38869-47-5 5g $32 2024-03-01 Buy
TCI Chemical M1449 1-(4-Methoxyphenyl)piperazine Dihydrochloride >98.0%(HPLC)(T) 38869-47-5 25g $90 2024-03-01 Buy
Cayman Chemical 14020 1-(4-Methoxyphenyl)piperazine (hydrochloride) ≥98% 38869-47-5 10mg $49 2026-04-30 Buy
Cayman Chemical 14020 1-(4-Methoxyphenyl)piperazine (hydrochloride) ≥98% 38869-47-5 50mg $110 2026-04-30 Buy
Product number Packaging Price Buy
M23004 25g $147 Buy
M1449 5g $32 Buy
M1449 25g $90 Buy
14020 10mg $49 Buy
14020 50mg $110 Buy

1-(4-Methoxyphenyl)piperazine dihydrochloride Chemical Properties,Uses,Production

Description

1-(4-Methoxyphenyl)piperazine dihydrochloride is a piperazine derivative with euphoric, stimulant properties comparable to those produced by amphetamine. It is assumed to have a mixed mechanism of action, with serotonergic and dopamine antagonistic properties in a similar fashion to 3,4-methylenedioxymethamphetamine. Also, its metabolism has been described. This product is intended for research and forensic purposes.

Chemical Properties

Off-White Powder

Uses

An intermediate in the synthesis of Itraconazole (I937500).

Uses

1-(4-Methoxyphenyl)piperazine dihydrochloride is a piperazine derivative with euphoric, stimulant properties comparable to those produced by amphetamine. It is assumed to have a mixed mechanism of action, with serotonergic and dopamine antagonistic properties in a similar fashion to 3,4-methylenedioxymethamphetamine. Also, its metabolism has been described. This product is intended for research and forensic purposes.

References

[1] ROLAND F STAACK  Hans H M. Metabolism of designer drugs of abuse.[J]. Current drug metabolism, 2005, 6 3: 259-274. DOI: 10.2174/1389200054021825
[2] M.D. ARBO  H. F C  M L Bastos. Piperazine compounds as drugs of abuse[J]. Drug and alcohol dependence, 2012, 122 3: Pages 174-185. DOI: 10.1016/j.drugalcdep.2011.10.007

1-(4-Methoxyphenyl)piperazine dihydrochloride Preparation Products And Raw materials

Global( 261)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TAIYUAN RHF CO.,LTD. +86 351 7031519 sales@RHFChem.com China 2334 56
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Sichuan Guanghan Bio-Tech Co., Ltd +86-28-86127071 info@sino-produce.com China 400 66
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62

View Lastest Price from 1-(4-Methoxyphenyl)piperazine dihydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-(4-Methoxyphenyl)piperazine dihydrochloride pictures 2025-12-24 1-(4-Methoxyphenyl)piperazine dihydrochloride
38869-47-5
1KG 99.0% 1000 tons Shaanxi Dideu Medichem Co. Ltd
1-(4-Methoxyphenyl)piperazine dihydrochloride pictures 2021-08-12 1-(4-Methoxyphenyl)piperazine dihydrochloride
38869-47-5
$10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
1-(4-methoxyphenyl)piperazine dihydrochloride  pictures 2020-02-26 1-(4-methoxyphenyl)piperazine dihydrochloride
38869-47-5
1KG 99.0%+ 100 tons Shaanxi Dideu Medichem Co. Ltd
TIMTEC-BB SBB003069 N-(4-METHOXYPHENYL)PIPERAZINE DIHYDROCHLORIDE PMPP DIHYDROCHLORIDE 1-(P-METHOXYPHENYL)PIPERAZINE DI HCL 1-(4-METHOXYLPHENYL)-PIPERAZINE DIHYDROCHLORIDE 1-(4-METHOXYPHENYL) PIPERAZINE 2HCL 1-(4-METHOXYPHENYL)PIPERAZINE DIHYDROCHLORIDE 1-(4-Methoxyphenyl)piperazine Dihydrochloride (discontinued see M266215) 4-(4-Methoxyphenyl)piperazine DiHydrochloride 4-(1-PIPERAZINYL)ANISOLE DIHYDROCHLORIDE 1-(4-Methoxyphenyl)piperazine dihydrochloride(MeOPP) 1-(4-methoxyphenyl)piperazine DIHCL 1-(4-Methoxyphenyl)piperazine dihydrocholoride Urapidil Impurity 2 (1-(4-Methoxyphenyl)piper 1-(4-methoxyphenyl)piperazine-1,4-diylium dichloride MeOPP 1-(4-METHOXYPHENYL)PIPERAZINE DIHYDROCHL ORIDE, TECH., 90% MethoxyPhenylPiperazineHydrochloride 1-(4-Methoxylphenyl)PiperazineHydrochloride 1-(4-Methoxyphenyl)piperazine dihydrochloride 97% 1-(4-methoxyphenylpiperazinejdihydrochloride N-(4-METHOXYPHENYL) PIPERAZINE 2HCL 1-(4-METHOXYPHENYL)PIPERAZINE DIHYDROCHLORIDE (PMPP) Piperazine, 1-(4-methoxyphenyl)-, dihydrochloride 1-(4-Methoxyphenyl)piperazine dihydrochloride,96% 1-(4-METHOXY PHENYL) PIPERAZINE DIHCL- PMEPP - + I 1(-P-METHOXY PHENYL PIPERAZINE) DIHYDROCHLORIDE 1-(4-Methoxyphenyl)piperazinedihydrochloride,97% 1-(4-Methoxyphenyl) Dihydrochloride 1-(4-Methoxyphenyl)piperazineDihydrochloride> UrapidilImpurity2piper Piperazine, 1-(4-methoxyphenyl)-, hydrochloride (1:2) 1-(4-methoxyphenyl)-Piperazine hydrochloride (1:2) 1-(4-Methoxyphenyl)piperazine dihydrochloride - [M93424] 38869-47-5 C11H18Cl2N2O C11H16N2O2ClH C11H16N2O2HCl C11H18N2Cl2O C11H16N2O2HClC11H18Cl2N2 AMINE Heterocyclic Building Blocks Piperazines Building Blocks Intermediates & Fine Chemicals Pharmaceuticals Pyrans, Piperidines & Piperazines Building Blocks Heterocyclic Building Blocks Piperidines, Piperidones, Piperazines Aromatics Heteroctcles Piperazines Pyrans, Piperidines &Piperazines Piperaizine Piperazine derivates API intermediates Nitrogen cyclic compounds