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4-Formyl-3-hydroxybenzoic acid

4-Formyl-3-hydroxybenzoic acid structure

CAS No.: 619-12-5

Chemical Name:: 4-Formyl-3-hydroxybenzoic acid

Synonyms: 4-CARBOXYSALICYALDEHYDE;4-Formyl-3-hydroxybenzoic acid;3-Hydroxy-4-formylbenzoic acid;Benzoic acid, 4-forMyl-3-hydroxy-;4-Formyl-3-hydroxybenzoic acid 97%;3-hydroxy-4-methanoyl-benzoic acid

CBNumber:: CB0749932

Molecular Formula:: C8H6O4

Molecular Weight:: 166.13

MDL Number:: MFCD05865188

MOL File:: 619-12-5.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:48:28

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4-Formyl-3-hydroxybenzoic acid Properties

Melting point	235-240 °C (lit.)
Boiling point	214.32°C (rough estimate)
Density	1.2208 (rough estimate)
refractive index	1.4611 (estimate)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
form	solid
pka	3.66±0.10(Predicted)
Appearance	White to light brown Solid
InChI	InChI=1S/C8H6O4/c9-4-6-2-1-5(8(11)12)3-7(6)10/h1-4,10H,(H,11,12)
InChIKey	FDDHFCWYCKQKGY-UHFFFAOYSA-N
SMILES	C(O)(=O)C1=CC=C(C=O)C(O)=C1
FDA UNII	B2G99FL7M4
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H317-H319
Precautionary statements	P280-P301+P312+P330-P302+P352-P305+P351+P338
PPE	dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes	Xn
Risk Statements	22-36/38-43
Safety Statements	26-36
WGK Germany	2
HS Code	2918999090
Storage Class	11 - Combustible Solids
Hazard Classifications	Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 Skin Sens. 1

4-Formyl-3-hydroxybenzoic acid price More Price(44)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	633461	4-Formyl-3-hydroxybenzoic acid 95%	619-12-5	1g	$213	2023-06-20	Buy
Sigma-Aldrich	633461	4-Formyl-3-hydroxybenzoic acid 95%	619-12-5	5g	$755	2023-06-20	Buy
Biosynth	FF66631	4-Formyl-3-hydroxybenzoic acid	619-12-5	500mg	$200	2026-06-04	Buy
Biosynth	FF66631	4-Formyl-3-hydroxybenzoic acid	619-12-5	1000mg	$340	2026-06-04	Buy
Biosynth	FF66631	4-Formyl-3-hydroxybenzoic acid	619-12-5	2000mg	$560	2026-06-04	Buy

Product number	Packaging	Price	Buy
633461	1g	$213	Buy
633461	5g	$755	Buy
FF66631	500mg	$200	Buy
FF66631	1000mg	$340	Buy
FF66631	2000mg	$560	Buy

4-Formyl-3-hydroxybenzoic acid Chemical Properties,Uses,Production

Uses

4-Formyl-3-hydroxybenzoic acid can be used as a reactant to prepare:

A pH-sensitive fluorescent probe 4,4′-(hydrazine-1,2-diylidene bis(methanylylidene)) bis(3-hydroxybenzoic acid (HDBB) by one-step condensation reaction with hydrazine.
2-Oxo-2H-1-benzopyran-3,7-dicarboxylic acid by condensation reaction with diethyl malonate.
Schiff base ligands for the preparation of stable and functional Schiff base metal complexes.

Synthesis

100-97-0

99-06-9

619-12-5

GENERAL METHOD: Hexamethylenetetramine (0.3 mmol) and cuprous oxide (0.15 mmol) were sequentially added to a solution of trifluoroacetic acid (5 mL) of the substrate (1a-1q, 0.15 mmol). The reaction mixture was heated to reflux for 5 h and subsequently cooled to room temperature. 3N hydrochloric acid (5 mL) was slowly added to the reaction system and stirring was continued for 1 hour. Upon completion of the reaction, the mixture was concentrated under reduced pressure to remove the solvent. The crude product was purified by silica gel column chromatography (200-300 mesh) to afford the target compound 4-formyl-3-hydroxybenzoic acid.

References

[1] Research on Chemical Intermediates, 2015, vol. 41, # 11, p. 8147 - 8158

4-Formyl-3-hydroxybenzoic acid Preparation Products And Raw materials

Raw materials

Hexamethylenetetramine 3-Hydroxybenzoic acid Hydrochloric acid Cuprous oxide Trifluoroacetic acid

Preparation Products

Methyl 4-formyl-3-hydroxybenzoate 4-cyano-3-hydroxybenzoic acid

4-Formyl-3-hydroxybenzoic acid Suppliers

Global( 110)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Nanjing Chemlin Chemical Co., Ltd	025-83697070 13770331960	info@chemlin.com.cn	China	16305	64
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
EnciPharmatech Co., Ltd	025-52714267-66 13813902930	stephen_shengll@hotmail.com	China	231	64
Shanghai Synthfine Chemical Co.,Ltd	15921303235	sales@synthfine.com	China	999	58
Hangzhou Sage Chemical Co., Ltd.	+86057186818502 13588463833	info@sagechem.com	China	10265	58
Shanghai Raise Chemical Technology Co.,Ltd	15026594951	rs@raise-chem.com	China	4905	55
Amatek Scientific Co. Ltd.	0512-56316828 4008675858	sales@amateksci.com	China	9849	55
Bide Pharmatech Ltd.	400-164-7117 18317119277	product02@bidepharm.com	China	40000	60
Wuxi Zhongkun Biochemical Technology Co., Ltd.	0510-85629785 18013409632;	sales@reading-chemicals.com	China	15165	58

Supplier	Advantage
Energy Chemical	61
Nanjing Chemlin Chemical Co., Ltd	64
Shanghai Hanhong Scientific Co.,Ltd.	64
EnciPharmatech Co., Ltd	64
Shanghai Synthfine Chemical Co.,Ltd	58
Hangzhou Sage Chemical Co., Ltd.	58
Shanghai Raise Chemical Technology Co.,Ltd	55
Amatek Scientific Co. Ltd.	55
Bide Pharmatech Ltd.	60
Wuxi Zhongkun Biochemical Technology Co., Ltd.	58

View Lastest Price from 4-Formyl-3-hydroxybenzoic acid manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2021-07-02	4-FORMYL-3-HYDROXYBENZOIC ACID 619-12-5	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd
	2019-07-06	4-FORMYL-3-HYDROXYBENZOIC ACID 619-12-5	$1.00	1KG	99%	1ton	Career Henan Chemical Co

4-FORMYL-3-HYDROXYBENZOIC ACID
619-12-5
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

4-FORMYL-3-HYDROXYBENZOIC ACID
619-12-5
$1.00
99%
Career Henan Chemical Co

4-Formyl-3-hydroxybenzoic acid Spectrum

4-FORMYL-3-HYDROXYBENZOIC ACID(619-12-5)¹HNMR

619-12-5(4-Formyl-3-hydroxybenzoic acid)Related Search:

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DIETHYL 2,5-DIHYDROXYTEREPHTHALATE Sennoside B Rhein 5-FORMYL-2-HYDROXYBENZOIC ACID 4-Formylbenzoic acid

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SENNIDINE A SENNIDINE B 4-(2,6-dihydroxybenzoyl)-3-formyl-5-hydroxybenzoic acid

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