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2-Hydroxy-4-fluoropyridine

2-Hydroxy-4-fluoropyridine Structure
2-Hydroxy-4-fluoropyridine structure
CAS No.
96530-75-5
Chemical Name:
2-Hydroxy-4-fluoropyridine
Synonyms
4-Fluoropyridin-2-ol;4-Fluoropyridin-2(1H)-one;uoropyridin-2-oL;4-fluoropyridin-2-o;4-fluoro-1H-pyridin-2-one;4-FLUORO-2(1H)-PYRIDINONE;2-Hydroxy-4-fluoropyridine;4-fluoro-2-hydroxypyridine;2(1H)-Pyridinone, 4-fluoro-;2-HYDROXY-4-FLUOROPYRIDINE ISO 9001：2015 REACH
CBNumber:
CB0777467
Molecular Formula:
C5H4FNO
Molecular Weight:
113.09
MDL Number:
MFCD07437952
MOL File:
96530-75-5.mol
MSDS File:
SDS
Last updated:2026-09-12 18:48:29
Request For Quotation

2-Hydroxy-4-fluoropyridine Properties

storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form solid
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
HS Code  2933399990

2-Hydroxy-4-fluoropyridine price More Price(48)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific PC201387 4-Fluoropyridin-2(1H)-one 97% 96530-75-5 250mg $28 2026-06-04 Buy
Apolloscientific PC201387 4-Fluoropyridin-2(1H)-one 97% 96530-75-5 1g $82 2026-06-04 Buy
Activate Scientific AS31870 4-Fluoropyridin-2-ol 97% 96530-75-5 1g $63 2026-06-04 Buy
Activate Scientific AS31870 4-Fluoropyridin-2-ol 97% 96530-75-5 5g $284 2026-06-04 Buy
Activate Scientific AS31870 4-Fluoropyridin-2-ol 97% 96530-75-5 25g $988 2026-06-04 Buy
Product number Packaging Price Buy
PC201387 250mg $28 Buy
PC201387 1g $82 Buy
AS31870 1g $63 Buy
AS31870 5g $284 Buy
AS31870 25g $988 Buy

2-Hydroxy-4-fluoropyridine Chemical Properties, Uses, Production

Synthesis

4-AMINO-PYRIDIN-2-OL

38767-72-5

2-HYDROXY-4-FLUOROPYRIDINE

96530-75-5

General procedure for the synthesis of 4-fluoropyridin-2-one from 4-aminopyridin-2-one: 4-amino-2-pyridinone (1.85 g, 16.8 mmol) was slowly added to a cooled solution of HF-pyridine complex (70%, 13.1 mL) at 0 °C. The mixture was cooled to -20 °C. Potassium tert-butoxide (3.0 mL, 25.2 mmol) was slowly added. The reaction mixture was stirred at -20 °C for 0.5 h and then slowly warmed to room temperature. The reaction was kept for 2 hours and then finally heated at 60 °C for 1 hour. The mixture was cooled to 0 °C and left to stand. Sodium carbonate (Na2CO3) was added to neutralize. The aqueous layer was extracted with ethyl acetate (5 times), the organic layers were combined, dried over anhydrous sodium sulfate (Na2SO4), filtered and concentrated under reduced pressure. Purification of the crude product by rapid chromatography on silica gel (dichloromethane/methanol: 95/5) afforded the target compound 4-fluoropyridin-2-one (1.14 g, 60% yield) as a colorless solid.

References

[1] Synlett, 2016, vol. 27, # 1, p. 67 - 69

2-Hydroxy-4-fluoropyridine Preparation Products And Raw materials

Raw materials

4-Amino-pyridin-2-ol

Preparation Products

2-Hydroxy-4-fluoropyridine Suppliers

Global Suppliers ( 81)
Supplier Tel Email Country ProdList Advantage
SpringPharma Tech Co.,Ltd +86-25-68710855, +86-25-68710897 sales@springpharma.net China 1260 62
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
Tianjin Jinyuda Chemical Co., Ltd. 022-58013646 13011382049 sales@jinyudachem.com China 1976 55
T&W GROUP 021-61551611 13296011611 contact@trustwe.com China 9884 58
Shanghai Topbiochem Technology Co., Ltd +86-21-60341587 sales@topbiochem.com China 6166 58
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 18201 56
Shanghai Yolne Chemical Co., Ltd. 021-62960152 934678158@qq.com China 9886 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai Taifu Pharmaceutical Technology Co. LTD 021-58111238 18930958102 sales@taifupharm.com China 509 55
Nanjing Duolong Bio-tech Co.,Ltd. 18905173768 52513593@qq.com China 2337 50
Supplier Advantage
SpringPharma Tech Co.,Ltd 62
Shanghai Sunway Pharmaceutical Technology Co., Ltd 57
Tianjin Jinyuda Chemical Co., Ltd. 55
T&W GROUP 58
Shanghai Topbiochem Technology Co., Ltd 58
9ding chemical ( Shanghai) Limited 56
Shanghai Yolne Chemical Co., Ltd. 55
Bide Pharmatech Ltd. 60
Shanghai Taifu Pharmaceutical Technology Co. LTD 55
Nanjing Duolong Bio-tech Co.,Ltd. 50

View Latest Price from 2-Hydroxy-4-fluoropyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-HYDROXY-4-FLUOROPYRIDINE pictures 2025-06-25 2-HYDROXY-4-FLUOROPYRIDINE
96530-75-5
 $1.10 1g 99.0% min 100 tons min Shaanxi Dideu Medichem Co. Ltd

2-Hydroxy-4-fluoropyridine Spectrum

2-HYDROXY-4-FLUOROPYRIDINE(96530-75-5)1HNMR2-HYDROXY-4-FLUOROPYRIDINE(96530-75-5)19FNMR

96530-75-5 (2-Hydroxy-4-fluoropyridine) Related Search:

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2-Hydroxypyridine

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4-FLUORO-2(1H)-PYRIDINONE 4-fluoro-1H-pyridin-2-one 4-fluoropyridin-2-o 4-fluoro-2-hydroxypyridine uoropyridin-2-oL 2(1H)-Pyridinone, 4-fluoro- 2-HYDROXY-4-FLUOROPYRIDINE ISO 9001：2015 REACH 2-Chloro-6-(trifluoromethyl)pyridin-5-yl)boronic acid 4-Fluoropyridin-2-ol 4-Fluoropyridin-2(1H)-one 2-Hydroxy-4-fluoropyridine 96530-75-5 Pyridines