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4-Amino-pyridin-2-ol

CAS No.
38767-72-5
Chemical Name:
4-Amino-pyridin-2-ol
Synonyms
4-aminopyridin-2(1H)-one;3-DEAZACYTOSINE;4-AMINO-2-PYRIDONE;4-AMino-2-pyridinol;4-Amino-pyridin-2-ol;4-amipyridin-2(1H)-one;4-AMino-1H-pyridin-2-one;4-amino-2(1H)-Pyridinone;4-Aminopyridin-2-ol 97%;2-Hydroxy-4-aMinopyridine
CBNumber:
CB1322509
Molecular Formula:
C5H6N2O
Molecular Weight:
110.11
MDL Number:
MFCD02682913
MOL File:
38767-72-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:49:11

4-Amino-pyridin-2-ol Properties

Melting point 219-221 °C(Solv: acetone (67-64-1))
Boiling point 310.7±35.0 °C(Predicted)
Density 1.208±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
form solid
pka 11.49±0.10(Predicted)
Appearance White to light brown Solid
InChI 1S/C5H6N2O/c6-4-1-2-7-5(8)3-4/h1-3H,(H3,6,7,8)
InChIKey SBQVQYPJWLJRQT-UHFFFAOYSA-N
SMILES Nc1ccnc(O)c1
CAS DataBase Reference 38767-72-5
UNSPSC Code 12352200
NACRES NA.21

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335-H302
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501
Hazard Codes  Xn
Risk Statements  22
WGK Germany  WGK 3
HS Code  2933399990
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral

4-Amino-pyridin-2-ol price More Price(68)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 260959 4-Amino-pyridin-2-ol Asreported 38767-72-5 500mg $347 2026-06-03 Buy
Usbiological 260959 4-Amino-pyridin-2-ol Asreported 38767-72-5 1g $548 2026-06-03 Buy
Usbiological 260959 4-Amino-pyridin-2-ol Asreported 38767-72-5 2g $755 2026-06-03 Buy
Usbiological 260959 4-Amino-pyridin-2-ol Asreported 38767-72-5 5g $1047 2026-06-03 Buy
Apolloscientific OR929418 4-Amino-1H-pyridin-2-one >98% 38767-72-5 1g $21 2026-06-04 Buy
Product number Packaging Price Buy
260959 500mg $347 Buy
260959 1g $548 Buy
260959 2g $755 Buy
260959 5g $1047 Buy
OR929418 1g $21 Buy

4-Amino-pyridin-2-ol Chemical Properties, Uses, Production

Uses

4-Amino-2-pyridone is used in the preparation of nucleoside analogues with antitumor and antiviral activity.

Synthesis

4-Amino-2-chloropyridine

14432-12-3

4-AMINO-PYRIDIN-2-OL

38767-72-5

General procedure for the synthesis of 4-aminopyridin-2-one from 2-chloro-4-aminopyridine: A mixture of 2-chloro-4-aminopyridine (127 mg, 1.0 mmol) and potassium hydroxide (280.6 mg, 5.0 mmol) in toluene (4.0 mL) was heated in a sealed tube and reacted for 72 hr at 170 °C. Upon completion of the reaction, the mixture was cooled to room temperature and the toluene solvent was subsequently removed by distillation under reduced pressure. The residue was purified by rapid chromatography on silica gel (eluent ratio dichloromethane/methanol/ammonia: 78/20/2) to afford the target product 4-aminopyridin-2-one (107 mg, 97% yield) as a light yellow solid.

References

[1] Synlett, 2016, vol. 27, # 1, p. 67 - 69
[2] Tetrahedron, 1999, vol. 55, # 41, p. 11985 - 11996

4-Amino-pyridin-2-ol Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 180)
Supplier Tel Email Country ProdList Advantage
Shanghai Boyle Chemical Co., Ltd. sales@boylechem.com China 2915 55
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Carbott PharmTech Inc. 0535-6385396 info@carbottpharm.com China 996 56
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078 sales@jingyan-chemical.com China 9963 60
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66

View Latest Price from 4-Amino-pyridin-2-ol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-AMino-1H-pyridin-2-one pictures 2026-09-18 4-AMino-1H-pyridin-2-one
38767-72-5
1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
4-AMINO-PYRIDIN-2-OL pictures 2026-08-20 4-AMINO-PYRIDIN-2-OL
38767-72-5
$1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
4-AMINO-PYRIDIN-2-OL pictures 2026-03-20 4-AMINO-PYRIDIN-2-OL
38767-72-5
$10.00 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd

4-Amino-pyridin-2-ol Spectrum

3-DEAZACYTOSINE 3-Deazacytosine 4-Amino-2-pyridone 4-Amino-2-hydroxy prydine 4-AMINO-2-PYRIDONE 4-AMINO-2-HYDROXYPYRIDINE 4-AMINO-2-HYDROXYPYRIDINE 98% 2(1H)-Pyridinone, 4-amino- 4-amino-2(1H)-Pyridinone 4-AMino-1H-pyridin-2-one 4-AMino-2-pyridinol 2-Hydroxy-4-aMinopyridine 4-amino-1,2-dihydropyridin-2-one 2-Pyridinol,4-Amino- (8Ci 4-AMINO-PYRIDIN-2-OL ISO 9001:2015 REACH 4-amipyridin-2(1H)-one 4-Aminopyridin-2-ol 97% 4-aminopyridin-2(1H)-one 4-Amino-pyridin-2-ol 38767-72-5 API intermediates Pyridines pharmacetical Pyridine Heterocycle-Pyridine series Nitrogen cyclic compounds