Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>(R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol

(R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol

(R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol Structure
(R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol structure
CAS No.
22348-32-9
Chemical Name:
(R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol
Synonyms
(R)-DIPHENYL(PYRROLIDIN-2-YL)METHANOL;RDPP;(R)-DIPHENYLPROLINOL;PYRROLIDINEMETHANOL;diphenyl-[(2R)-pyrrolidin-2-yl]methanol;(R)-(+)-2-(DIPHENYLHYDROXYMETHYL)PYRROLIDINE;(R)-(+)-ALPHA,ALPHA-DIPHENYL-2-PYRROLIDINEMETHANOL;(R)-D2PM;idinemethanoL;(R)-(+)-2-(Diphenylh
CBNumber:
CB1101689
Molecular Formula:
C17H19NO
Molecular Weight:
253.35
MDL Number:
MFCD00077754
MOL File:
22348-32-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 23:02:37
Request For Quotation

(R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol Properties

Melting point 77-80 °C
alpha 59 º (589nm, c=3, MeOH 25 ºC)
Boiling point 396.54°C (rough estimate)
Density 1.0078 (rough estimate)
refractive index 58 ° (C=2, MeOH)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility almost transparency in Chloroform
form solid
pka 13.15±0.29(Predicted)
color white to off-white
optical activity [α]20/D +69°, c = 3 in chloroform
BRN 4353363
InChI 1S/C17H19NO/c19-17(16-12-7-13-18-16,14-8-3-1-4-9-14)15-10-5-2-6-11-15/h1-6,8-11,16,18-19H,7,12-13H2/t16-/m1/s1
InChIKey OGCGXUGBDJGFFY-MRXNPFEDSA-N
SMILES OC([C@H]1CCCN1)(c2ccccc2)c3ccccc3
CAS DataBase Reference 22348-32-9(CAS DataBase Reference)
FDA UNII D56JS74WW2
NIST Chemistry Reference (R)-alpha-(2-pyrrolidinyl)benzhydryl alcohol(22348-32-9)
UNSPSC Code 12352005
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
F  10-34
TSCA  No
HS Code  29221990
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
1
2 0

(R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol price More Price(68)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 382337 (R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol 98% 22348-32-9 1g $422 2026-04-30 Buy
Sigma-Aldrich 382337 (R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol 98% 22348-32-9 5g $571 2026-04-30 Buy
TCI Chemical D2365 (R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethanol >98.0%(GC)(T) 22348-32-9 1g $94 2026-04-30 Buy
TCI Chemical D2365 (R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethanol >98.0%(GC)(T) 22348-32-9 5g $326 2026-04-30 Buy
Usbiological 273968 (R)-(+)-Diphenyl-2-pyrrolidinemethanol Asreported 22348-32-9 2g $333 2026-06-03 Buy
Product number Packaging Price Buy
382337 1g $422 Buy
382337 5g $571 Buy
D2365 1g $94 Buy
D2365 5g $326 Buy
273968 2g $333 Buy

(R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol Chemical Properties, Uses, Production

Chemical Properties

white to faintly yellow crystalline powder

Uses

suzuki reaction

Uses

Used to prepare the corresponding oxazaborolidines for the borane-mediated asymmetric reduction of ketones.

Definition

ChEBI: (r)-alpha,alpha-diphenyl-2-pyrrolidinemethanol is a diarylmethane.

Synthesis

Draw 14 kg of tetrahydrofuran into the reaction kettle. 61.5 kg of a 34% strength solution of phenylmagnesium chloride in tetrahydrofuran was added to the reaction vessel to initiate agitation and cooling cycles. The control temperature is 10 to 60 °C. The dropping time was controlled for 5 to 6 hours, and stirring was continued for 1 hour. Pump 24 kg of concentrated hydrochloric acid (mass concentration 36%) into the matching drip tank of the reaction kettle. constantly dropping, the dropping time is controlled for 1 hour, and the dropping process control temperature does not exceed 45 ° C. After the addition was completed, stirring was continued for 8 hours.Cool down to -5 ° C ~ 5 ° C to obtain (R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol, a total of 17.2 kg, yield 85%.

(R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol synthesis

137496-68-5
22348-32-9
Synthesis of (R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol from 1-Pyrrolidinecarboxylic acid, 2-(hydroxydiphenylmethyl)-,1,1-dimethylethyl ester, (2R)-

(R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol Preparation Products And Raw materials

Raw materials

Preparation Products

R-2-[[[(1,1-diMethylethyl)diMethylsilyl]oxy] diphenylMethyl]-Pyrrolidine

(R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol Suppliers

Global Suppliers ( 511)
Supplier Tel Email Country ProdList Advantage
Shanghai Forxine Pharmaceutical Co., Ltd. 21-21-64961388 18918697718 service@forxine.com China 65 60
China Synchem Technology Co.,Ltd. +86-0552-4929304 +86-18055277008 sales@cnsynchem.com China 55 65
Viwit Pharmaceutical Co., Ltd. 0632-0632-2980981 15063270987 service.china3@viwit.com China 121 55
Hubei Xinkang Pharmaceutical Chemical Co., Ltd 027-027-59308705 18871579363 1248680011@qq.com China 9279 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
JIANGXI AIFEIMU TECHNOLOGY CO.,LTD 793-33899567 13735087952 sales@afmpharm.com China 51 61
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Supplier Advantage
Shanghai Forxine Pharmaceutical Co., Ltd. 60
China Synchem Technology Co.,Ltd. 65
Viwit Pharmaceutical Co., Ltd. 55
Hubei Xinkang Pharmaceutical Chemical Co., Ltd 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
INTATRADE GmbH 66
JIANGXI AIFEIMU TECHNOLOGY CO.,LTD 61
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81

Related articles

View Latest Price from (R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethanol pictures 2026-09-16 (R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethanol
22348-32-9
 0.99 RongNa Biotechnology Co.,Ltd
2,2-diphenyl-(2R)-2-pyrrolidinemethanol pictures 2025-09-23 2,2-diphenyl-(2R)-2-pyrrolidinemethanol
22348-32-9
 10kg 99%min 1 tons Hangzhou Verychem Science And Technology Co.Ltd
(R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethanol pictures 2025-06-27 (R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethanol
22348-32-9
 1KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd

(R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol Spectrum

(R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethanol(22348-32-9)MS(R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethanol(22348-32-9)1HNMR(R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethanol(22348-32-9)13CNMR(R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethanol(22348-32-9)IR1(R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethanol(22348-32-9)IR2(R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethanol(22348-32-9)Raman

22348-32-9 ((R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol) Related Search:

Diethylstilbestrol Biphenyl Fosfomycin tromethamine Ketorolac tromethamine (R)-TERT-LEUCINOL
Pyrrolidine Dexketoprofen trometamol Hydrogenated Cottonseed Oil D(-)Prolinol (S)-(-)-α,α-Diphenyl-2-pyrrolidinemethanol
(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole (R)-alpha,alpha-Diphenylmethylprolinol (R)-Di-2-naphthylprolinol (R)-o-Tolyl-CBS-oxazaborolidine, 0.5M i& (R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol
(R)-2-(Methoxydiphenylmethyl)pyrrolidine (R)-α,α-Bis(3,5-dichlorophenyl)-2-pyrrolidinemethanol hydrochloride (R,R)-(-)-2,6-Bis[2-(hydroxydiphenylmethyl)-1-pyrrolidinyl-methyl]-4-methylphenol

1of4

2-PYRROLIDINEMETHANOL, A,A-DIPHENYL- 2-Pyrrolidinemethanol, α,α-diphenyl-, (2R)- (2R)-α,α-diphenyl-2-Pyrrolidinemethanol (R)-1-DIPHENYL-PROLINOL (R)-(+)-2-(DIPHENYLHYDROXYMETHYL)-PYRROLIDIN (R)-2-(DIPHENYLHYDROXYMETHYL)PYRROLIDINE (R)-(+)-ɑ,ɑ-Diphenylprolinol, 99% ALPHA,ALPHA-DIPHENYL-D-PROLINOL A,A-DIPHENYL-D-PROLINOL alpha,alpha-diphenyl-2-pyrrolidinemethanol (R)-α,α-Diphenyl-2-pyrrolidinemethanol, (R)-2-(Diphenylhydroxymethyl)pyrrolidine α,α-Diphenyl-D-prolinol, (R)-2-(Diphenylhydroxymethyl)pyrrolidine (R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethanol,98% (R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol ,98% α,α-Diphenyl-D-prolinol,(R)-α,α-Diphenyl-2-pyrrolidinemethanol, (R)-2-(Diphenylhydroxymethyl)pyrrolidine (R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol,α,α-Diphenyl-D-prolinol, (R)-2-(Diphenylhydroxymethyl)pyrrolidine (2R)-(+)-2-[Hydroxy(diphenyl)methyl]pyrrolidine (R)-(+)-2-(Diphenylh alpha-Diphenyl-2-pyrrolidineMethanol Diphenyl[(2R)-(+)-pyrrolidin-2-yl]methanol, (R)-(+)-alpha,alpha-Diphenylprolinol alpha,alpha-Diphenyl-D-prolinol (R)-(+)-2-(Diphenylhydroxymethyl)pyrrolidine -(+)-2-(DiphenylhydroxyMethyl)pyrrolidine (R)-(+)-α,α-DiphenyL idinemethanoL R(+)-A,A-DIPHENYLPROLINOL R-(+)-ALFA,ALFA-DIPHENYL-2-PYRROLIDINE METHANOL (R)-ALPHA,ALPHA-DIPHENYL-2-PYRROLIDINEMETHANOL (R)-(+)-ALPHA,ALPHA-DIPHENYL-(2-PYRROLIDINYL)-METHANOL (R)-(+)-ALPHA,ALPHA-DIPHENYLPROLINOL (R)-(+)-DIPHENYL-2-PYRROLIDINEMETHANOL (R)-(+)-DIPHENYLPYRROLIDINEMETHANOL ?-DIPHENYL(PYRROLIDIN-2-YL)METHANOL (R)-(+)-A,A-DIPHENYL-2-PYRROLIDINEMETHANOL (r)-(+)-à,à-diphenyl-2-pyrrolidinemethanol (r)-(+)-à,à-diphenylprolinol α,α-diphenyl-d-prolinol 2,2-DIPHENYL-(2R)-2-PYRROLIDINEMETHANOL PYRROLIDINEMETHANOL (R)-(+)-alpha,alpha-diphenyl-2-pyrrolidine (R)-(+)-ALPHA,ALPHA-DIPHENYL-2-PRRROLIDINE METHANOL 99.0+% (+)-Diphenyl[(2R)-pyrrolidin-2-yl]methanol, (+)-alpha,alpha-Diphenyl-D-prolinol (R)-(+)- alpha,alpha-Diphenyl-2-yrrolidine Methanol -DIPHENYL(PYRROLIDIN-2-YL)METHANOL (R)-(+)-alpha,alpha-Diphenyl-2-Pymolidinemethanol (R)-(+)-α,α-Diphenyl-2-pyrrolidineMethanol 98% 2-PyrrolidineMethanol,a,a-diphenyl-, (2R)- (R)-(+)-2-(Diphenylhydroxymethyl)pyrrolidine alpha,alpha-Diphenyl-D-prolinol 2-Pyrrolidinemethanol, .alpha.,.alpha.-diphenyl-, (2R)- (R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol (R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethanol 98% (R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol, >=99% (R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol> (R)-(+)-a,a-2-Pyrrolidinemethanol R-(+)-α,α-Diphenylprolinol (R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol (R)-(+)- α,α-2-pyrrolidinemethanol iphenyl-[(2R)-pyrrolidin-2-yl]methanol (R)-1,1-Diphenylprolinol