Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>Pyrido[2,3-d]pyrimidin-7(8H)-one, 4-[[(1R)-1-[3-(difluoromethyl)-2-fluorophenyl]ethyl]amino]-6-(cis-1,4-dihydroxycyclohexyl)-2-methyl-

Pyrido[2,3-d]pyrimidin-7(8H)-one, 4-[[(1R)-1-[3-(difluoromethyl)-2-fluorophenyl]ethyl]amino]-6-(cis-1,4-dihydroxycyclohexyl)-2-methyl-

Pyrido[2,3-d]pyrimidin-7(8H)-one, 4-[[(1R)-1-[3-(difluoromethyl)-2-fluorophenyl]ethyl]amino]-6-(cis-1,4-dihydroxycyclohexyl)-2-methyl- Structure
Pyrido[2,3-d]pyrimidin-7(8H)-one, 4-[[(1R)-1-[3-(difluoromethyl)-2-fluorophenyl]ethyl]amino]-6-(cis-1,4-dihydroxycyclohexyl)-2-methyl- structure
CAS No.
2755415-30-4
Chemical Name:
Pyrido[2,3-d]pyrimidin-7(8H)-one, 4-[[(1R)-1-[3-(difluoromethyl)-2-fluorophenyl]ethyl]amino]-6-(cis-1,4-dihydroxycyclohexyl)-2-methyl-
Synonyms
SOS1-IN-7;Pyrido[2,3-d]pyrimidin-7(8H)-one, 4-[[(1R)-1-[3-(difluoromethyl)-2-fluorophenyl]ethyl]amino]-6-(cis-1,4-dihydroxycyclohexyl)-2-methyl-
CBNumber:
CB113090747
Molecular Formula:
C23H25F3N4O3
Molecular Weight:
462.46
MDL Number:
MOL File:
2755415-30-4.mol
MSDS File:
SDS
Last updated:2026-05-11 19:39:08
Request For Quotation

Pyrido[2,3-d]pyrimidin-7(8H)-one, 4-[[(1R)-1-[3-(difluoromethyl)-2-fluorophenyl]ethyl]amino]-6-(cis-1,4-dihydroxycyclohexyl)-2-methyl- Properties

Boiling point 609.0±65.0 °C(Predicted)
Density 1.48±0.1 g/cm3(Predicted)
pka 12.55±0.40(Predicted)

Pyrido[2,3-d]pyrimidin-7(8H)-one, 4-[[(1R)-1-[3-(difluoromethyl)-2-fluorophenyl]ethyl]amino]-6-(cis-1,4-dihydroxycyclohexyl)-2-methyl- Chemical Properties, Uses, Production

Uses

SOS1-IN-7 (compound 18-p1) is a potent SOS1 inhibitor with IC50s of 20 and 67 nM for SOS1-G12D and SOS1-G12V, respectively[1].

IC 50

SOS1-G12D: 20 nM (IC50); SOS1-G12V: 67 nM (IC50)

References

[1] Pyridine-pyrimidine derivative, preparation method therefor and pharmaceutical use thereof. WO2021249519A1.

Pyrido[2,3-d]pyrimidin-7(8H)-one, 4-[[(1R)-1-[3-(difluoromethyl)-2-fluorophenyl]ethyl]amino]-6-(cis-1,4-dihydroxycyclohexyl)-2-methyl- Preparation Products And Raw materials

Raw materials

Preparation Products

Pyrido[2,3-d]pyrimidin-7(8H)-one, 4-[[(1R)-1-[3-(difluoromethyl)-2-fluorophenyl]ethyl]amino]-6-(cis-1,4-dihydroxycyclohexyl)-2-methyl- Suppliers

Global Suppliers ( 2)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29873 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
Supplier Advantage
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58

View Latest Price from Pyrido[2,3-d]pyrimidin-7(8H)-one, 4-[[(1R)-1-[3-(difluoromethyl)-2-fluorophenyl]ethyl]amino]-6-(cis-1,4-dihydroxycyclohexyl)-2-methyl- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
SOS1-IN-7 pictures 2026-05-11 SOS1-IN-7
2755415-30-4
 $2140.00-3520.00 10g TargetMol Chemicals Inc.
  • SOS1-IN-7 pictures
  • SOS1-IN-7
    2755415-30-4
  • $2140.00-3520.00
  • TargetMol Chemicals Inc.

2755415-30-4 (Pyrido[2,3-d]pyrimidin-7(8H)-one, 4-[[(1R)-1-[3-(difluoromethyl)-2-fluorophenyl]ethyl]amino]-6-(cis-1,4-dihydroxycyclohexyl)-2-methyl-) Related Search:

2-Propen-1-one, 1-[(3S)-4-[(7R)-7-[6-amino-4-methyl-3-(trifluoromethyl)-2-pyridinyl]-6-chloro-8-fluoro-2-[[(2S)-1-methyl-2-pyrrolidinyl]methoxy]-4-quinazolinyl]-3-methyl-1-piperazinyl]- NAV2729 1,4-Oxazepin-5(2H)-one, 4-[3-[[2-[[2-ethyl-4-(4-methyl-1-piperazinyl)phenyl]amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]propyl]tetrahydro- RMC-7977 EHT1864
RMC5127

1of2

Pyrido[2,3-d]pyrimidin-7(8H)-one, 4-[[(1R)-1-[3-(difluoromethyl)-2-fluorophenyl]ethyl]amino]-6-(cis-1,4-dihydroxycyclohexyl)-2-methyl- SOS1-IN-7 2755415-30-4