ChemicalBook >> CAS DataBase List >>2-Propen-1-one, 3-(4-chlorophenyl)-1-(1,3,4,9-tetrahydro-6-methoxy-1-methyl-2H-pyrido[3,4-b]indol-2-yl)-, (2E)-

2-Propen-1-one, 3-(4-chlorophenyl)-1-(1,3,4,9-tetrahydro-6-methoxy-1-methyl-2H-pyrido[3,4-b]indol-2-yl)-, (2E)-

2-Propen-1-one, 3-(4-chlorophenyl)-1-(1,3,4,9-tetrahydro-6-methoxy-1-methyl-2H-pyrido[3,4-b]indol-2-yl)-, (2E)- structure

CAS No.: 2891824-14-7

Chemical Name:: 2-Propen-1-one, 3-(4-chlorophenyl)-1-(1,3,4,9-tetrahydro-6-methoxy-1-methyl-2H-pyrido[3,4-b]indol-2-yl)-, (2E)-

Synonyms: Dyrk1A-IN-10;2-Propen-1-one, 3-(4-chlorophenyl)-1-(1,3,4,9-tetrahydro-6-methoxy-1-methyl-2H-pyrido[3,4-b]indol-2-yl)-, (2E)-

CBNumber:: CB114685894

Molecular Formula:: C22H21ClN2O2

Molecular Weight:: 380.87

MDL Number:

MOL File:: 2891824-14-7.mol

MSDS File:: SDS

Last updated:2025-04-18 09:51:37

Request For Quotation

2-Propen-1-one, 3-(4-chlorophenyl)-1-(1,3,4,9-tetrahydro-6-methoxy-1-methyl-2H-pyrido[3,4-b]indol-2-yl)-, (2E)- Properties

Boiling point	630.6±55.0 °C(predicted)
Density	1.287±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka	16.94±0.40(predicted)

2-Propen-1-one, 3-(4-chlorophenyl)-1-(1,3,4,9-tetrahydro-6-methoxy-1-methyl-2H-pyrido[3,4-b]indol-2-yl)-, (2E)- Chemical Properties, Uses, Production

Uses

Dyrk1A-IN-10 (compound B4) is a DYRK1A inhibitor with antidiabetic activity. Dyrk1A-IN-10 can promote pancreatic β-cell proliferation, increase insulin secretion, and lower blood sugar[1].

References

[1] Li Guan, et al. "Design, synthesis, and biological evaluation of β-carboline-cinnamic acid derivatives as DYRK1A inhibitors in the treatment of diabetes." Bioorganic Chemistry (2024): 107676. DOI:10.1016/j.bioorg.2024.107676

2-Propen-1-one, 3-(4-chlorophenyl)-1-(1,3,4,9-tetrahydro-6-methoxy-1-methyl-2H-pyrido[3,4-b]indol-2-yl)-, (2E)- Preparation Products And Raw materials

Raw materials

Preparation Products

2-Propen-1-one, 3-(4-chlorophenyl)-1-(1,3,4,9-tetrahydro-6-methoxy-1-methyl-2H-pyrido[3,4-b]indol-2-yl)-, (2E)- Suppliers

Global Suppliers ( 1)

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

Supplier	Advantage
TargetMol Chemicals Inc.	58

2891824-14-7 (2-Propen-1-one, 3-(4-chlorophenyl)-1-(1,3,4,9-tetrahydro-6-methoxy-1-methyl-2H-pyrido[3,4-b]indol-2-yl)-, (2E)-) Related Search:

Thieno[3,2-d]pyrimidine-2,4-diamine, N4-(5-cyclopropyl-1H-pyrazol-3-yl)-N2-(phenylmethyl)- YK-2-69 2-Amino-4-hydroxypyrrolo[2,3-d]pyrimidine 2,6-Pyridinediamine, 4-[2-methyl-3-(2,2,2-trifluoroethyl)-3H-imidazo[4,5-b]pyridin-5-yl]- Dyrktide

AZ191

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2-Propen-1-one, 3-(4-chlorophenyl)-1-(1,3,4,9-tetrahydro-6-methoxy-1-methyl-2H-pyrido[3,4-b]indol-2-yl)-, (2E)- Dyrk1A-IN-10 2891824-14-7