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(S)-2-(Aminomethyl)-1-(tert-butoxycarbonyl)pyrrolidine

(S)-2-(Aminomethyl)-1-(tert-butoxycarbonyl)pyrrolidine Structure
(S)-2-(Aminomethyl)-1-(tert-butoxycarbonyl)pyrrolidine structure
CAS No.
119020-01-8
Chemical Name:
(S)-2-(Aminomethyl)-1-(tert-butoxycarbonyl)pyrrolidine
Synonyms
(S)-1-BOC-2-(AMINOMETHYL)PYRROLIDINE;-1-Boc-pyrroL;CAS:119020-01-8;(S)-2-AminomethyL;RARECHEM AL BW 2320;(S)-1-Boc-2-(aminomethyl)...;(S)-N'-BOC-2-Aminomethylpirrolidine;(S)-2-AMINOMETHYL-1-BOC-PYRROLIDINE;(S)-N-Boc-2-(aminomethyl)pyrrolidine;(s)-1-Boc-2-(AMinoMethyl ) Pyrolidine
CBNumber:
CB1184725
Molecular Formula:
C10H20N2O2
Molecular Weight:
200.28
MDL Number:
MFCD03419257
MOL File:
119020-01-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 23:11:51
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(S)-2-(Aminomethyl)-1-(tert-butoxycarbonyl)pyrrolidine Properties

Boiling point 98-112℃/1mm
Density 1.044±0.06 g/cm3(Predicted)
refractive index 1.4670-1.4710
storage temp. 2-8°C
solubility Miscible with N-methylpyrrolidinone.
pka 9.91±0.29(Predicted)
form clear liquid
color Colorless to Almost colorless
BRN 8905233
InChI 1S/C10H20N2O2/c1-10(2,3)14-9(13)12-6-4-5-8(12)7-11/h8H,4-7,11H2,1-3H3/t8-/m0/s1
InChIKey SOGXYCNKQQJEED-QMMMGPOBSA-N
SMILES CC(C)(C)OC(=O)N1CCC[C@H]1CN
CAS DataBase Reference 119020-01-8(CAS DataBase Reference)
UNSPSC Code 12352005
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Exclamation Mark (GHS07)
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H314
Precautionary statements  P260-P270-P280-P301+P312-P303+P361+P353-P305+P351+P338
PPE Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Hazard Codes  Xi,N,C
Risk Statements  36/37/38-51/53-34-22
Safety Statements  26-36/37/39-61-45
RIDADR  3259
WGK Germany  3
HazardClass  8
PackingGroup  Ⅲ
HS Code  29339900
Storage Class 8A - Combustible corrosive hazardous materials
Hazard Classifications Acute Tox. 4 Oral
Skin Corr. 1B
Limited Quantities 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
1
3 0

(S)-2-(Aminomethyl)-1-(tert-butoxycarbonyl)pyrrolidine price More Price(62)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical A2473 (S)-2-(Aminomethyl)-1-(tert-butoxycarbonyl)pyrrolidine >98.0%(GC)(T) 119020-01-8 1g $112 2026-04-30 Buy
Usbiological 261476 S-2-(Aminomethyl)-1-(tert-butoxycarbonyl)pyrrolidine Asreported 119020-01-8 500mg $306 2026-06-03 Buy
Usbiological 261476 S-2-(Aminomethyl)-1-(tert-butoxycarbonyl)pyrrolidine Asreported 119020-01-8 1g $419 2026-06-03 Buy
Usbiological 261476 S-2-(Aminomethyl)-1-(tert-butoxycarbonyl)pyrrolidine Asreported 119020-01-8 2g $561 2026-06-03 Buy
Usbiological 261476 S-2-(Aminomethyl)-1-(tert-butoxycarbonyl)pyrrolidine Asreported 119020-01-8 5g $802 2026-06-03 Buy
Product number Packaging Price Buy
A2473 1g $112 Buy
261476 500mg $306 Buy
261476 1g $419 Buy
261476 2g $561 Buy
261476 5g $802 Buy

(S)-2-(Aminomethyl)-1-(tert-butoxycarbonyl)pyrrolidine Chemical Properties, Uses, Production

Description

(S)-2-(Aminomethyl)-1-(tert-butoxycarbonyl)pyrrolidine is an optically active compound primarily used in organic synthesis for preparing small-molecule protein synthesis regulators or molecular glue degraders.

Chemical Properties

Solid

Uses

(S)-2-Aminomethyl-1-Boc-pyrrolidine acts as an intermediate in organic synthesis. It is also used as a chiral and heterocyclic building block in synthetic chemistry.

Synthesis

(S)-2-(AzidoMethyl)-1-Boc-pyrrolidine

168049-26-1

(S)-1-N-Boc-2-(aminomethyl)pyrrolidine

119020-01-8

GENERAL METHOD: Under stirring conditions, azide derivatives 9a or 9b (4.03 mmol) were dissolved in THF (1 mL), followed by the addition of solid triphenylphosphine (Ph3P, 4.03 mmol) and water (H2O, 6.04 mmol). The reaction mixture was stirred continuously for 12 h at room temperature. After completion of the reaction, the solvent was removed by concentration under reduced pressure. The crude product was purified by rapid column chromatography on silica gel with an eluent ratio of methanol-dichloromethane (9:1).

References

[1] Synthesis, 2005, # 14, p. 2407 - 2413
[2] Angewandte Chemie - International Edition, 2011, vol. 50, # 48, p. 11382 - 11385
[3] Synthetic Communications, 2011, vol. 41, # 17, p. 2517 - 2523
[4] Tetrahedron Letters, 2010, vol. 51, # 40, p. 5281 - 5286
[5] Phosphorus, Sulfur and Silicon and the Related Elements, 2013, vol. 188, # 4, p. 509 - 511

(S)-2-(Aminomethyl)-1-(tert-butoxycarbonyl)pyrrolidine Preparation Products And Raw materials

Raw materials

(R)-tert-butyl 2-((1,3-dioxoisoindolin-2-yl)Methyl)pyrrolidine-1-carboxylate (S)-2-(AzidoMethyl)-1-Boc-pyrrolidine Water Triphenylphosphine Tetrahydrofuran

Preparation Products

(S)-1-Boc-2-(methylaminomethyl)-pyrrolidine (S)-2-[(2-Chloro-acetylaMino)-Methyl]-pyrrolidine-1-carboxylic acid tert-butyl ester

(S)-2-(Aminomethyl)-1-(tert-butoxycarbonyl)pyrrolidine Suppliers

Global Suppliers ( 227)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
ITIC MEDCHEM(SUZHOU) CO.,LTD. 0512-68323967 18015559028 sales@iticmedchem.com China 528 61
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. +86-21-54098501 sales@sinch.com.cn China 11592 64
Sichuan Guanghan Bio-Tech Co., Ltd +86-28-86127071 info@sino-produce.com China 400 66
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
ITIC MEDCHEM(SUZHOU) CO.,LTD. 61
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56
Capot Chemical Co., Ltd 66
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. 64
Sichuan Guanghan Bio-Tech Co., Ltd 66

View Latest Price from (S)-2-(Aminomethyl)-1-(tert-butoxycarbonyl)pyrrolidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(S)-1-Boc-2-(aminomethyl)pyrrolidine pictures 2026-08-25 (S)-1-Boc-2-(aminomethyl)pyrrolidine
119020-01-8
 $1.10-9.90 1kg 99%min 100kg ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
(S)-1-N-Boc-2-(aminomethyl)pyrrolidine pictures 2025-06-27 (S)-1-N-Boc-2-(aminomethyl)pyrrolidine
119020-01-8
 1KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd
(S)-1-N-Boc-2-(aminomethyl)pyrrolidine pictures 2025-06-20 (S)-1-N-Boc-2-(aminomethyl)pyrrolidine
119020-01-8
 $40.00 1kg 0.99 10 tons Hebei Yanxi Chemical Co., Ltd.

(S)-2-(Aminomethyl)-1-(tert-butoxycarbonyl)pyrrolidine Spectrum

(S)-1-N-Boc-2-(aminomethyl)pyrrolidine(119020-01-8)1HNMR

119020-01-8 ((S)-2-(Aminomethyl)-1-(tert-butoxycarbonyl)pyrrolidine) Related Search:

Methyl anthranilate N-Vinyl-2-pyrrolidone tert-Butyl acetate Diisobutyl phthalate Butyl acetate
Cyhalofop-butyl Buprofezin Urethane Diethylene glycol monobutyl ether 2-Butoxyethanol
N-Methyl-2-pyrrolidone Pyrrolidine 4-Aminobenzoic acid Butyl acrylate tert-Butanol
Polyvinylpyrrolidone Butyl oleate Polyurethane

1of4

tert-Butyl 2-(1-aminoethyl)-1-pyrrolidinecarboxylate (S)-TERT-BUTYL-2-(AMINOMETHYL)PYRROLIDINE-1-CARBOXYLATE RARECHEM AL BW 2320 (S)-2-AMINOMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER (S)-2-(AMINOMETHYL)-1-N-BOC-PYRROLIDINE (S)-2-AMINOMETHYL-1-BOC-PYRROLIDINE (S)-1-BOC-2-(AMINOMETHYL)PYRROLIDINE (S)-1-N-Boc-2-(aminomethyl)pyrrolidine (2S)-2-AMINOMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER (S)-N'-BOC-2-Aminomethylpirrolidine (S)-2-(Aminomethyl)pyrrolidine, N1-BOC protected (S)-(2-Aminomethyl)-1-N-Boc-pyrrolidin tert-Butyl (2S)-2-(aminomethyl)pyrrolidine-1-carboxylate (S)-1-Boc-2-(aminomethyl)... (2S)-2-(Aminomethyl)pyrrolidine, N1-BOC protected (S)-2-(Aminomethyl)-1-(tert-butoxycarbonyl)pyrrolidine tert-Butyl (S)-2-(aminomethyl)-1-pyrrolidinecarboxylate (S)-2-(AMINOMETHYL)-1-N-BOC-PYYROLIDINE tert-Butyl (2S)-2-(aminomethyl)pyrrolidine-1-carboxylate, (2S)-2-(Aminomethyl)-1-(tert-butoxycarbonyl)pyrrolidine (S)-2-(Aminomethyl)-1-Boc-pyrrolidine tert-Butyl (S)-2-(Aminomethyl)-1-pyrrolidinecarboxylate (S)-2-(Aminomethyl)-1-pyrrolidinecarboxylic Acid tert-Butyl Ester tert-Butyl (S)-2-aMinoMethylpyrrolidine-1-carboxylate (s)-1-Boc-2-(AMinoMethyl ) Pyrolidine 2-(S)-aMinoMethyl-pyrrolidine-1-carboxylic acid tert-butyl ester 1-Pyrrolidinecarboxylic acid, 2-(aminomethyl)-, 1,1-dimethylethyl ester, (2S)- (S)-2-(Aminomethyl)-1-Boc-pyrrolidine 97% (S)-N-Boc-2-(aminomethyl)pyrrolidine (S)-N-Boc-2-(aminomethyl)pyrrolidine,99%e.e. (S)-2-(Aminomethyl)-1-(tert-butoxycarbonyl)pyrrolidine > (S)-2-AminomethyL -1-Boc-pyrroL (S)-2-(Aminomethyl)-1-pyrrolidinecarboxylic Acid tert-Butyl Ester CAS:119020-01-8 (S)-2-(Aminomethyl)-1-Boc-pyrrolidine (S)-2-(Aminomethyl)-1-Boc-pyrrolidine, CAS 119020-01-8 119020-01-8 199020-01-8 11902-01-8 pharmacetical Pyrrole&Pyrrolidine&Pyrroline