2,3-Difluorobenzoic acid
- CAS No.
- 4519-39-5
- Chemical Name:
- 2,3-Difluorobenzoic acid
- Synonyms
- BUTTPARK 45\01-40;CHEMPACIFIC 39931;2,3-Difluorobenzoic;RARECHEM AL BO 0251;TIMTEC-BB SBB006679;3-Difluorobenzoic acid;2,3-DIFLUOROBENZOIC ACID;2,3-DIFLUOROBENZONIC ACID;2,3-DifluorobenzoicAcid>2,3-Difluorobenzoicacid,98%
- CBNumber:
- CB1216459
- Molecular Formula:
- C7H4F2O2
- Molecular Weight:
- 158.1
- MDL Number:
- MFCD00010267
- MOL File:
- 4519-39-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 163-165 °C (lit.) |
|---|---|
| Boiling point | 248.1±20.0 °C(Predicted) |
| Density | 1.3486 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| form | powder to crystal |
| pka | 2.93±0.10(Predicted) |
| color | White to Almost white |
| Water Solubility | slightly soluble |
| BRN | 2640781 |
| InChI | InChI=1S/C7H4F2O2/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3H,(H,10,11) |
| InChIKey | JLZVIWSFUPLSOR-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C1=CC=CC(F)=C1F |
| CAS DataBase Reference | 4519-39-5(CAS DataBase Reference) |
| EPA Substance Registry System | Benzoic acid, 2,3-difluoro- (4519-39-5) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38-37/38-36 | |||||||||
| Safety Statements | 26-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29163990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
2,3-Difluorobenzoic acid price More Price(64)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 263516 | 2,3-Difluorobenzoic acid 98% | 4519-39-5 | 10g | $90.6 | 2026-04-30 | Buy |
| Sigma-Aldrich | 263516 | 2,3-Difluorobenzoic acid 98% | 4519-39-5 | 1g | $28.9 | 2023-06-20 | Buy |
| TCI Chemical | D2058 | 2,3-Difluorobenzoic Acid >98.0%(GC)(T) | 4519-39-5 | 5g | $61 | 2026-04-30 | Buy |
| TCI Chemical | D2058 | 2,3-Difluorobenzoic Acid >98.0%(GC)(T) | 4519-39-5 | 25g | $202 | 2026-04-30 | Buy |
| Apolloscientific | PC2654 | 2,3-Difluorobenzoic acid 98% | 4519-39-5 | 25g | $75 | 2026-06-04 | Buy |
2,3-Difluorobenzoic acid Chemical Properties, Uses, Production
Chemical Properties
white to off-white powder
Uses
2,3-Difluorobenzoic acid has been used as a tracer for determining the extent of recovery of materials injected into oil wells.
General Description
2,3-Difluorobenzoic acid forms dimers that are stabilized by hydrogen bonds. It is used in pharmaceuticals, pesticides, and liquid crystal material intermediates.
Synthesis
124-38-9
126163-64-2
4519-39-5
Carbon dioxide gas was passed into a reaction solution containing lithium 2,3-difluorobenzene (CAS:126163-64-2) at a temperature of -65 to -60 °C, ensuring that the molar ratio of carbon dioxide to lithium 2,3-difluorobenzene was 1.5:1. The reaction was maintained at this temperature for 4 hours. Upon completion of the reaction, water was added for hydrolysis at a mass ratio of water to reaction solution of 1.5:1 and the hydrolysis temperature was controlled at 15-20 °C. Subsequently, the organic solvent was removed by heating distillation and the reaction mixture was concentrated. The temperature was adjusted to 20-22 °C and the reaction mixture was acidified with a 10% hydrochloric acid solution with a molar ratio of hydrochloric acid to lithium 2,3-difluorobenzene of 2:1. After acidification, the reaction was kept for 3 hours. The reaction mixture was cooled to 0°C and the crystals formed were collected by diafiltration. The crystals were washed with a buffer solution of pH=2 and subsequently dried to give 2,3-difluorobenzoic acid. The purity of the final product was 99.5% and the yield was 90%.
References
[1] Patent: CN108658759, 2018, A. Location in patent: Paragraph 0032; 0037
2,3-Difluorobenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zibo Run Hang Seng material Technology Co., LTD | 13561657928 13561657928 | 2388773670@qq.com | China | 294 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
View Latest Price from 2,3-Difluorobenzoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-16 | 2,3-difluorobenzoic acid
4519-39-5
|
$290.00 | 1KG | 98% | 300MT/year | Speranza Chemical Co., Ltd. | |
 |
2026-08-25 | 2,3-Difluorobenzoic acid
4519-39-5
|
$2.20-8.80 | 1kg | 99%min | 1000kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2026-03-20 | 2,3-Difluorobenzoic acid
4519-39-5
|
$9.90 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- 2,3-difluorobenzoic acid
4519-39-5
- $290.00
- 98%
- Speranza Chemical Co., Ltd.
-
- 2,3-Difluorobenzoic acid
4519-39-5
- $2.20-8.80
- 99%min
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- 2,3-Difluorobenzoic acid
4519-39-5
- $9.90
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
