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N-Boc-cis-4-Hydroxy-L-proline methyl ester

N-Boc-cis-4-Hydroxy-L-proline methyl ester structure

CAS No.: 102195-79-9

Chemical Name:: N-Boc-cis-4-Hydroxy-L-proline methyl ester

Synonyms: (2S,4S)-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate;1-tert-butyl 2-methyl (2S,4S)-4-hydroxypyrrolidine-1,2-dicarboxylate;BOC-CIS-HYP-OME;cis-Boc-Hyp-OMe;Boc-cis-L-Hyp-OMe;Boc-L-cis-Hyp-OMe;N-Boc-cis-Hyp-Ome;Boc-cis-hyp-ome ,97%;N-Boc-cis-4-Hydroxy-L;BOC-CIS-HYDROXYPROLINE-OME

CBNumber:: CB1248508

Molecular Formula:: C11H19NO5

Molecular Weight:: 245.27

MDL Number:: MFCD00237541

MOL File:: 102195-79-9.mol

MSDS File:: SDS

Last updated:2026-02-02 18:10:39

Product description	Number	Pack Size	Price
N-Boc-cis-4-hydroxy-L-proline methyl ester 97%	654000	1g	$55.1
N-Boc-cis-4-hydroxy-L-proline methyl ester 97%	654000	5g	$175
N-(tert-Butoxycarbonyl)-cis-4-hydroxy-L-proline Methyl Ester >97.0%(GC)	B3987	1g	$34
N-(tert-Butoxycarbonyl)-cis-4-hydroxy-L-proline Methyl Ester >97.0%(GC)	B3987	5g	$103
(2S,4S)-4-Hydroxypyrrolidine-1,2-dicarboxylicAcid1-tert-ButylEster2-MethylEster	H656565	1g	$140
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N-Boc-cis-4-Hydroxy-L-proline methyl ester Properties

Melting point	82-86 °C (lit.)
Boiling point	335.2±42.0 °C(Predicted)
Density	1.216±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,2-8°C
pka	14.27±0.40(Predicted)
form	powder to crystal
color	White to Almost white
optical activity	-63.6200°(C=1.011g/100ml ETOH)
Water Solubility	Insoluble in water.
Major Application	peptide synthesis
InChI	InChI=1S/C11H19NO5/c1-11(2,3)17-10(15)12-6-7(13)5-8(12)9(14)16-4/h7-8,13H,5-6H2,1-4H3/t7-,8-/m0/s1
InChIKey	SVSSZFBZFUSINI-SFYZADRCSA-N
SMILES	N1(C(OC(C)(C)C)=O)C[C@@H](O)C[C@H]1C(OC)=O
CAS DataBase Reference	102195-79-9(CAS DataBase Reference)
UNSPSC Code	12352209
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H317-H319-H335

Precautionary statements

P280-P301+P312+P330-P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Hazard Codes

Risk Statements

22-36/37/38-43

Safety Statements

26-36

WGK Germany

HS Code

29339900

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
Skin Sens. 1
STOT SE 3

NFPA 704

	1
2		0

N-Boc-cis-4-Hydroxy-L-proline methyl ester price More Price(53)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	654000	N-Boc-cis-4-hydroxy-L-proline methyl ester 97%	102195-79-9	1g	$55.1	2025-07-31	Buy
Sigma-Aldrich	654000	N-Boc-cis-4-hydroxy-L-proline methyl ester 97%	102195-79-9	5g	$175	2025-07-31	Buy
TCI Chemical	B3987	N-(tert-Butoxycarbonyl)-cis-4-hydroxy-L-proline Methyl Ester >97.0%(GC)	102195-79-9	1g	$34	2025-07-31	Buy
TCI Chemical	B3987	N-(tert-Butoxycarbonyl)-cis-4-hydroxy-L-proline Methyl Ester >97.0%(GC)	102195-79-9	5g	$103	2025-07-31	Buy
TRC	H656565	(2S,4S)-4-Hydroxypyrrolidine-1,2-dicarboxylicAcid1-tert-ButylEster2-MethylEster	102195-79-9	1g	$140	2021-12-16	Buy

Product number	Packaging	Price	Buy
654000	1g	$55.1	Buy
654000	5g	$175	Buy
B3987	1g	$34	Buy
B3987	5g	$103	Buy
H656565	1g	$140	Buy

N-Boc-cis-4-Hydroxy-L-proline methyl ester Chemical Properties,Uses,Production

Chemical Properties

White solid

Uses

Used as a local anaesthetic. Used as therapeutic agents. Employed as important intermediates in various areas such as peptide synthesis, polymer chemistry..

Uses

2S,4S)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl Ester 2-Methyl Ester oline scaffold.

reaction suitability

reaction type: Boc solid-phase peptide synthesis

IC 50

Non-cleavable Linker

N-Boc-cis-4-Hydroxy-L-proline methyl ester Preparation Products And Raw materials

Raw materials

Sodium benzoate Hexane Acetone Sodium chloride Di-tert-butyl dicarbonate

Potassium carbonate Triethylamine Chloroform Methanesulfonyl chloride Ethyl acetate

Hydrochloric acid Sodium bicarbonate Dichloromethane Methanol Dimethyl sulfoxide

L-Hydroxyproline Magnesium sulfate Thionyl chloride PETROLEUM ETHER

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Preparation Products

N-Boc-cis-4-Hydroxy-L-proline methyl ester Suppliers

Global( 314)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
PRISUN PHARMATECH CO.,LTD	+86-021-54326183-8001 +8618917565227	prisun@prisunpharma.com	China	215	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20128	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Chembon Pharmaceutical Co., Ltd.	+86-28-8425-2981		CHINA	722	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29831	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
HaBo Hong Kong Co., Limited.	+86-25-18512596065	info@habotech.com	CHINA	933	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Chengdu Pukang Biotechnology Co., Ltd	028-82550498	export@pu-kang.com	CHINA	210	58

Supplier	Advantage
PRISUN PHARMATECH CO.,LTD	58
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Chembon Pharmaceutical Co., Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Jinan Carbotang Biotech Co.,Ltd.	58
HaBo Hong Kong Co., Limited.	58
Accela ChemBio Inc.	58
Chengdu Pukang Biotechnology Co., Ltd	58

View Lastest Price from N-Boc-cis-4-Hydroxy-L-proline methyl ester manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-02-02	N-Boc-4-hydroxy-L-proline methyl ester 102195-79-9	US $0.00 / removed		≥98%	10g	TargetMol Chemicals Inc.
2026-02-02	N-Boc-4-hydroxy-L-proline methyl ester 102195-79-9	US $0.00 / removed		≥98%	10g	TargetMol Chemicals Inc.
2025-09-25	(2S,4S)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate 102195-79-9	US $200.00-1.00 / KG	1KG	99%, 99.5% Sublimated	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd

N-Boc-4-hydroxy-L-proline methyl ester
102195-79-9
US $0.00 / removed
≥98%
TargetMol Chemicals Inc.

N-Boc-4-hydroxy-L-proline methyl ester
102195-79-9
US $0.00 / removed
≥98%
TargetMol Chemicals Inc.

(2S,4S)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate
102195-79-9
US $200.00-1.00 / KG
99%, 99.5% Sublimated
Henan Fengda Chemical Co., Ltd

N-Boc-cis-4-Hydroxy-L-proline methyl ester Spectrum

N-Boc-cis-4-Hydroxy-L-proline methyl ester(102195-79-9)¹HNMR

102195-79-9(N-Boc-cis-4-Hydroxy-L-proline methyl ester)Related Search:

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Methyl acrylate N-Boc-cis-4-Hydroxy-L-proline Thiophanate-methyl Methyl Methyl bromide

N-Boc-trans-4-tosyloxy-L-proline methyl ester (2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate N-Boc-trans-4-Hydroxy-L-proline methyl ester

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(2S,4S)-N-Boc-cis-4-hydroxy-L-proline methyl ester N-Boc-cis-4-hydroxy-L-proline methyl ester, >97.0%(GC) (2S,4S)-N-Boc-4-hydroxyproline methyl ester 1-tert-butyl 2-methyl cis-4-hydroxypyrrolidine-1,2-dicarboxylate cis-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate N-T-BOC-CIS-4-HYDROXY-L-PROLINE METHYL ESTER N-ALPHA-T-BUTOXYCARBONYL-CIS-4-HYDROXY-L-PROLINE METHYL ESTER N-Boc-cis-4-hydroxy-L-proline Methyl ester, 97%, 97% Boc-L-cis-4-Hydroxyproline methyl ester 1-tert-butyl 2-methyl (2S,4S)-4-hydroxypyrrolidine-1,2-dicarboxylate N-t-BOC-cis-4-HYDROXYL-L-PROLINE METHYL ESTER cis-N-Boc-4-hydroxy-L-proline Methyl Ester Methyl (4S)-N-Boc-4-hydroxy-L-prolinate O1-tert-Butyl O2-methyl (2S,4S)-4-hydroxypyrrolidine-1,2-dicarboxylate Boc-cis-L-Hyp-OMe cis-N-Boc-4-hydroxy-L-proline Methyl Ester,99%e.e. N-ALPHA-T-BUTOXYCARBONYL-CIS-L-4-HYDROXYPROLINE METHYL ESTER N-BOC-CIS-4-HYDROXY-L-PROLINE METHYL ESTER N-BOC-CIS-4-HYDROXY-L-PROLINE METHYL ES& METHYL CIS-1-BOC-4-HYDROXY-L-PROLINATE Boc-cis-hydroxyproline methyl ester (2S,4S)-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate BOC-CIS-HYDROXYPROLINE-OME BOC-CIS-HYP-OME BOC-CIS-L-4-HYDROXYPROLINE METHYL ESTER Boc-cis-4-Hydroxy-L-proline methyl ester Boc-cis-hyp-ome ,97% 1-tert-butyl 2-Methyl (2S)-4-hydroxypyrrolidine-1,2-dicarboxylate N-Boc-cis-4-Hydro×y-L-proline Methyl ester (2S,4S)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl Ester 2-Methyl Ester N-Boc-cis-4-hydroxy-L-proline Methyl ester N-Boc-cis-4-hydroxy-L-proline Methyl ester cis-Boc-Hyp-OMe N-(tert-Butoxycarbonyl)-cis-4-hydroxy-L-proline Methyl Ester 1,2-Pyrrolidinedicarboxylicacid, 4-hydroxy-, 1-(1,1-diMethylethyl) 2-Methyl ester, (2S,4S)- N-Boc-cis-4-hydroxy-L-proline methyl, 97% Boc-L-cis-Hyp-OMe N-Boc-cis-Hyp-Ome 1-o-tert-butyl 2-o-methyl (2s,4s)-4-hydroxypyrrolidine-1,2-dicarboxylate N-(tert-Butoxycarbonyl)-cis-4-hydroxy-L-prolineMethylEster> N-Boc-cis-4-Hydroxy-L (2S,4S)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl 2-Methyl Ester N-Boc-cis-4-Hydroxy-L-proline methyl ester USP/EP/BP (2S,4S)-1-tert-Butoxycarbonyl-4-hydroxypyrrolidine-2-carboxylic acid methyl ester 2-Methyl 1-(2-methyl-2-propanyl) (2S,4S)-4-hydroxy-1,2-pyrrolidinedicarboxylate (2S,4S)-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate/N-Boc-cis-4-Hydroxy-L-proline methyl ester N-Boc-cis-4-hydroxy-L-proline methyl ester (2S,4S)-1-BOC-4-Hydroxy-pyrrolidine-2-carboxylic acid methyl ester 102195-79-9 Unnatural Amino Acid Derivatives Specialty Synthesis Peptide Synthesis Proline Derivatives Heterocycles Peptide Synthesis Proline Derivatives Unnatural Amino Acid Derivatives