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ChemicalBook >> CAS DataBase List >>E3 Ligase Ligand-Linker Conjugates 20

E3 Ligase Ligand-Linker Conjugates 20

E3 Ligase Ligand-Linker Conjugates 20 Structure
E3 Ligase Ligand-Linker Conjugates 20 structure
CAS No.
1950635-15-0
Chemical Name:
E3 Ligase Ligand-Linker Conjugates 20
Synonyms
Thalidomide-O-amido-C8-NH2;Cereblon Ligand-Linker Conjugates 2;E3 Ligase Ligand-Linker Conjugates 20;N-(8-aminooctyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide;N-(8-Aminooctyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetamide;N-(8-aminooctyl)-2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}acetamide;Acetamide, N-(8-aminooctyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-;N-(8-Aminooctyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide?, Thalidomide-O-amido-C8-NH2
CBNumber:
CB13386469
Molecular Formula:
C23H30N4O6
Molecular Weight:
458.51
MDL Number:
MFCD31630819
MOL File:
1950635-15-0.mol
Last updated:2025-04-17 18:22:24
Product description Number Pack Size Price
E3 Ligase Ligand-Linker Conjugates 20 >98% DC50053 100mg $550
E3 Ligase Ligand-Linker Conjugates 20 >98% DC50053 250mg $850
E3 Ligase Ligand-Linker Conjugates 20 >98% DC50053 1g $1800
E3LigaseLigand-LinkerConjugates20 CSN23772 100mg $298
E3LigaseLigand-LinkerConjugates20 CSN23772 250mg $521
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E3 Ligase Ligand-Linker Conjugates 20 Properties

Boiling point 762.8±60.0 °C(Predicted)
Density 1.295±0.06 g/cm3(Predicted)
pka 10.68±0.40(Predicted)

E3 Ligase Ligand-Linker Conjugates 20 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
DC Chemicals DC50053 E3 Ligase Ligand-Linker Conjugates 20 >98% 1950635-15-0 100mg $550 2026-05-24 Buy
DC Chemicals DC50053 E3 Ligase Ligand-Linker Conjugates 20 >98% 1950635-15-0 250mg $850 2026-05-24 Buy
DC Chemicals DC50053 E3 Ligase Ligand-Linker Conjugates 20 >98% 1950635-15-0 1g $1800 2026-05-24 Buy
CSNpharm CSN23772 E3LigaseLigand-LinkerConjugates20 1950635-15-0 100mg $298 2021-12-16 Buy
CSNpharm CSN23772 E3LigaseLigand-LinkerConjugates20 1950635-15-0 250mg $521 2021-12-16 Buy
Product number Packaging Price Buy
DC50053 100mg $550 Buy
DC50053 250mg $850 Buy
DC50053 1g $1800 Buy
CSN23772 100mg $298 Buy
CSN23772 250mg $521 Buy

E3 Ligase Ligand-Linker Conjugates 20 Chemical Properties,Uses,Production

Uses

Thalidomide-O-amido-C8-NH2 (Cereblon Ligand-Linker Conjugates 2), a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs[1].

IC 50

Cereblon

References

[1] James Bradner, et al. Methods to induce targeted protein degradation through bifunctional molecules. WO 2017024317 A2.

E3 Ligase Ligand-Linker Conjugates 20 Preparation Products And Raw materials

Raw materials

Preparation Products

E3 Ligase Ligand-Linker Conjugates 20 Suppliers

Global( 14)Suppliers
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TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32466 58
Jilin Chinese Academy of Sciences-yanshen Technology 		+undefined18143011203 info@chemextension.com China 42056 58
Shanghai Chaolan Chemical Technology Center QQ：65489617 19372819560 Sales@ATKchemical.com China 9627 58
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1639 58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 043180534350 19917294565 et@chemextension.com China 4467 58
Henan Weitixi Chemical Technology Co., Ltd 0371-53370800 18037197114 3807961510@qq.com China 9893 58
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Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 9999 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29844 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Jilin Chinese Academy of Sciences-yanshen Technology 		58
Shanghai Chaolan Chemical Technology Center 58
Jilin Province Woda Biotechnology Co., Ltd. 58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 58
Henan Weitixi Chemical Technology Co., Ltd 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 58
https://hanhongsci.com/ 58
Accela ChemBio Co.,Ltd. 58
TargetMol Chemicals Inc. 58

1950635-15-0(E3 Ligase Ligand-Linker Conjugates 20)Related Search:

E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate E3 Ligase Ligand-Linker Conjugates 22 Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride Thalidomide-linker 14 N-(4-azidobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide
1H-Isoindole-1,3(2H)-dione, 4-[2-(2-aminoethoxy)ethoxy]-2-(2,6-dioxo-3-piperidinyl)- Cereblon Ligand 1 E3 Ligase Ligand-Linker Conjugates 21 E3 Ligase Ligand-Linker Conjugates 19 Thalidomide-O-PEG4-Propargyl
Thalidomide-linker 10 Acetamide, 2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-N-3,6,9,12-tetraoxapentadec-14-yn-1-yl- Thalidomide-O-amido-C4-NH2 hydrochloride Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride Thalidomide-O-amido-C8-NH2 hydrochloride
Thalidomide-O-PEG4-Boc tert-butyl 3,3'-(2-aMino-2-((3-tert-butoxy-3-oxopropoxy)Methyl)propane-1,3-diyl)bis(oxy)dipropanoate E3 Ligase Ligand-Linker Conjugates 24 (TFA)

1of4

E3 Ligase Ligand-Linker Conjugates 20 Cereblon Ligand-Linker Conjugates 2 Thalidomide-O-amido-C8-NH2 N-(8-aminooctyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide Acetamide, N-(8-aminooctyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- N-(8-aminooctyl)-2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}acetamide N-(8-Aminooctyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide?, Thalidomide-O-amido-C8-NH2 N-(8-Aminooctyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetamide 1950635-15-0