2-Fluoro-3-pyridinemethanamine
- CAS No.
- 859164-64-0
- Chemical Name:
- 2-Fluoro-3-pyridinemethanamine
- Synonyms
- RARECHEM AL BW 2476;2-Fluoro-3-pyridinemethanamine;(2-fluoro-3-pyridyl)methanamine;(2-FLUOROPYRIDIN-3-YL)METHANAMINE;(2-FLUOROPYRIDIN-3-YL)METHANAMINE HCL;2-Fluoro-3-pyridinemethanamine,hydrochloride;2-Fluoropyridine-3-methanamine Hydrochloride;(2-fluoro-3-pyridyl)methanamine hydrochloride;2-fluoro-3-pyridineMethanaMine dihydrochloride;2-fluoro-3-(aminomethyl)pyridine hydrochloride
- CBNumber:
- CB1372832
- Molecular Formula:
- C6H7FN2
- Molecular Weight:
- 126.13
- MDL Number:
- MFCD20524895
- MOL File:
- 859164-64-0.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H335-H315-H312 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P280-P302+P352-P312-P322-P363-P501-P264-P280-P302+P352-P321-P332+P313-P362 |
2-Fluoro-3-pyridinemethanamine price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS33253 | 2-Fluoro-3-pyridinemethanamine HCl 97% | 859164-64-0 | 1g | $116 | 2026-06-04 | Buy |
| Activate Scientific | AS33253 | 2-Fluoro-3-pyridinemethanamine HCl 97% | 859164-64-0 | 5g | $345 | 2026-06-04 | Buy |
| Activate Scientific | AS33253 | 2-Fluoro-3-pyridinemethanamine HCl 97% | 859164-64-0 | 25g | $1065 | 2026-06-04 | Buy |
| Matrix Scientific | 314394 | (2-Fluoropyridin-3-yl)methanamine hydrochloride | 859164-64-0 | 250.00mg | $49 | 2026-05-19 | Buy |
| Matrix Scientific | 314394 | (2-Fluoropyridin-3-yl)methanamine hydrochloride | 859164-64-0 | 1.00g | $76 | 2026-05-19 | Buy |
2-Fluoro-3-pyridinemethanamine Chemical Properties, Uses, Production
Application
2-Fluoro-3-pyridinemethylmethylamine is an amine organic compound that can be used as a pharmaceutical synthesis intermediate.
Synthesis
3939-13-7
859164-64-0
General procedure for the synthesis of 2-fluoro-3-pyridinylmethylamine from 2-fluoro-3-cyanopyridine: first, C-(2-fluoro-pyridin-3-yl)-methylamine hydrochloride was prepared. Concentrated hydrochloric acid (0.46 mL) was slowly added to a suspension of methanol (10 mL) containing 2-fluoro-3-cyanopyridine (0.34 g, 2.8 mmol) and 5% Pd/C (0.5 g) at room temperature. Subsequently, the reaction suspension was stirred continuously for 6 hours under a hydrogen atmosphere at 1 atmosphere. Upon completion of the reaction, the reaction mixture was filtered and the filtrate concentrated. Ether was added to the concentrated residue and HCl gas was passed through the suspension bulge. The resulting precipitate was filtered and dried to give the target product 2-fluoro-3-pyridylmethylmethylamine (0.37 g, 82% yield). Substance spectral analysis (ES) of the product showed a m/z of 127.1 ([M + H]+). The NMR hydrogen spectrum (400 MHz, DMSO-d6) data were as follows: δ 8.65 (broad single peak, 3H), 8.24 (multiple peaks, 1H), 8.16 (multiple peaks, 1H), 7.41 (multiple peaks, 1H), 4.06 (multiple peaks, 2H).
References
[1] Patent: WO2005/66126, 2005, A1. Location in patent: Page/Page column 59
2-Fluoro-3-pyridinemethanamine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Ennopharm Co., Ltd. | +86 (21) 6435-5022 | China | 4263 | 65 | |
| Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12323 | 58 |
| ShangHai AmK Pharmaceutical Technology Co., Ltd. | 微信 18019252918 18019252918 | sale@amkchem.com | China | 14982 | 55 |
| Struchem Co., Ltd. | 0512-63009836 18994340901 | helen@struchem.com | China | 3970 | 60 |
| Shanghai Chenzhu Pharmaceutical Co., Ltd. | 13162380607 | 1696175688@qq.com | China | 834 | 55 |
| Shijiazhuang Sdyano Fine Chemical Co., Ltd. | 0311-89250318 031166536426; | master@sjzsdyn.com | China | 3491 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| ChengDu TongChuangYuan Pharmaceutical Co.Ltd | 028-83379370 13880556291 | tcy@tcypharm.com | China | 8696 | 58 |
| Zhengzhou Acme Chemical Co., Ltd. | 0371-0371-55629727 13323845623 | 2885676761@qq.com | China | 9957 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
