8-Chloroquinoline
- CAS No.
- 611-33-6
- Chemical Name:
- 8-Chloroquinoline
- Synonyms
- 8-chloro-quinolin;8-CHLOROQUINOLINE;8-Chloroquinoline>Quinoline, 8-chloro-;8-Chloroquinoline ,99%;8-Chloroquinoline, 98%+;8-Chloro-1-azanaphthalene;8-Chloroquinoline ISO 9001：2015 REACH
- CBNumber:
- CB1376643
- Molecular Formula:
- C9H6ClN
- Molecular Weight:
- 163.6
- MDL Number:
- MFCD00047618
- MOL File:
- 611-33-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | -20 °C |
|---|---|
| Boiling point | 288.5 °C |
| Density | 1.28 |
| refractive index | 1.6450-1.6480 |
| Flash point | >110℃ |
| storage temp. | Inert atmosphere,Room Temperature |
| pka | 2.33±0.17(Predicted) |
| form | Liquid |
| Specific Gravity | 1.27 |
| color | Clear yellow to brown |
| Water Solubility | SOLUBLE |
| InChI | 1S/C9H6ClN/c10-8-5-1-3-7-4-2-6-11-9(7)8/h1-6H |
| InChIKey | RUSMDMDNFUYZTM-UHFFFAOYSA-N |
| SMILES | Clc1cccc2cccnc12 |
| CAS DataBase Reference | 611-33-6(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | U4UPA3J2CR |
| NIST Chemistry Reference | Quinoline, 8-chloro-(611-33-6) |
| EPA Substance Registry System | Quinoline, 8-chloro- (611-33-6) |
| UNSPSC Code | 12352200 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H315-H319 | |||||||||
| Precautionary statements | P264-P270-P280-P301+P310-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi,T | |||||||||
| Risk Statements | 36/37/38-25 | |||||||||
| Safety Statements | 37/39-26-36/37/39-45 | |||||||||
| RIDADR | UN 2811 6.1 / PGIII | |||||||||
| WGK Germany | WGK 3 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29334900 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 3 Oral Eye Irrit. 2 Skin Irrit. 2 |
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| NFPA 704 |
|
8-Chloroquinoline price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | CDS004725 | 8-Chloroquinoline AldrichCPR | 611-33-6 | 100mg | $77.9 | 2026-04-30 | Buy |
| TCI Chemical | C0284 | 8-Chloroquinoline >98.0%(GC) | 611-33-6 | 5g | $135 | 2026-04-30 | Buy |
| TCI Chemical | C0284 | 8-Chloroquinoline >98.0%(GC) | 611-33-6 | 25g | $476 | 2026-04-30 | Buy |
| Apolloscientific | OR42189 | 8-Chloroquinoline >98% | 611-33-6 | 5g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR42189 | 8-Chloroquinoline >98% | 611-33-6 | 25g | $33 | 2026-06-04 | Buy |
8-Chloroquinoline Chemical Properties, Uses, Production
Chemical Properties
CLEAR YELLOW TO BROWN LIQUID
Definition
ChEBI: 8-chloroquinoline is a member of quinolines and an organochlorine compound.
Synthesis Reference(s)
The Journal of Organic Chemistry, 52, p. 1673, 1987 DOI: 10.1021/jo00385a006
Synthesis
4470-83-1
611-33-6
General procedure for the synthesis of 8-chloroquinoline from 2,8-dichloroquinoline: PdCl2 (dppf), PdCl2 (tbpf), or (A.caPhos) PdCl2 was used as catalyst. First, the halogenated heterocyclic compound (0.66 mmol) was dissolved in anhydrous THF (13.2 mL) and degassed by drumming argon for several minutes. Subsequently, PdCl2 (dppf) (27.0 mg, 0.033 mmol, 5.0 mol%), TMEDA (0.130 g, 1.12 mmol, 1.7 equiv) and NaBH4 (42.4 mg, 1.12 mmol, 1.7 equiv) were added sequentially. The reaction mixture was stirred under argon protection at room temperature for an appropriate time and then post-treated in the usual way.
Purification Methods
Purify it by crystallisation of its ZnCl2 complex (m 228o) from aqueous EtOH. [Beilstein 20 III/IV 3381, 20/7 V 315.]
References
[1] Journal of Molecular Catalysis A: Chemical, 2014, vol. 393, p. 191 - 209
8-Chloroquinoline Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| future industrial shanghai co., ltd | 400-0066400 13621662912 | sales@jonln.com | China | 1989 | 65 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| ShangHai DEMO Chemical Co.,Ltd | 400-021-7337 2355568890 | sales@demochem.com | China | 2569 | 57 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
View Latest Price from 8-Chloroquinoline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | 8-Chloroquinoline
611-33-6
|
$1.10 | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | |
 |
2026-07-15 | 8-Chloroquinoline
611-33-6
|
1kg | 98% | 1000kgs | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2025-04-04 | 8-Chloroquinoline
611-33-6
|
1KG | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. |
-
- 8-Chloroquinoline
611-33-6
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 8-Chloroquinoline
611-33-6
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- 8-Chloroquinoline
611-33-6
- 98%
- Henan Aochuang Chemical Co.,Ltd.
