ChemicalBook >> CAS DataBase List >>AB-423
AB-423
- CAS No.
- 1572510-80-5
- Chemical Name:
- AB-423
- Synonyms
- AB-423;CS-2686;AB-423 (AB423;AB423;AB-423;AB 423;AB-423, 10 mM in DMSO;D-Gluconic acid (solution) (51.205%w/w in water);AB 423,HBV,AB423,inhibit,Hepatitis B virus,AB-423,Inhibitor;5-[[(2R)-butan-2-yl]sulfamoyl]-N-(3,4-difluorophenyl)-2-fluorobenzamide;N-(3,4-Difluorophenyl)-2-fluoro-5-[[[(1R)-1-methylpropyl]amino]sulfonyl]benzamide;Benzamide, N-(3,4-difluorophenyl)-2-fluoro-5-[[[(1R)-1-methylpropyl]amino]sulfonyl]-
- CBNumber:
- CB13960102
- Molecular Formula:
- C17H17F3N2O3S
- Molecular Weight:
- 386.39
- MDL Number:
- MFCD31657418
- MOL File:
- 1572510-80-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-07-17 09:03:53
| Density | 1.372±0.06 g/cm3(Predicted) |
|---|---|
| storage temp. | Store at -20°C |
| solubility |
DMSO:88.5(Max Conc. mg/mL);229.04(Max Conc. mM) Ethanol:77.0(Max Conc. mg/mL);199.28(Max Conc. mM) |
| form | Solid |
| pka | 10.84±0.70(Predicted) |
| color | White to off-white |
| CAS DataBase Reference | 1572510-80-5 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
AB-423 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0043473 | AB-423 99.31% | 1572510-80-5 | 5mg | $108 | 2026-06-04 | Buy |
| ChemScene | CS-0043473 | AB-423 99.31% | 1572510-80-5 | 10mg | $179 | 2026-06-04 | Buy |
| ChemScene | CS-0043473 | AB-423 99.31% | 1572510-80-5 | 25mg | $379 | 2026-06-04 | Buy |
| ChemScene | CS-0043473 | AB-423 99.31% | 1572510-80-5 | 50mg | $520 | 2026-06-04 | Buy |
| ChemScene | CS-0043473 | AB-423 99.31% | 1572510-80-5 | 100mg | $706 | 2026-06-04 | Buy |
AB-423 Chemical Properties, Uses, Production
Uses
N-(3,4-Difluorophenyl)-2-fluoro-5-[[[(1R)-1-methylpropyl]amino]sulfonyl]benzamide, is an inhibitor of HBV capsid assembly. AB-423 shows inhibitory effect on rcDNA production in AML12-HBV10 and HepDE19 cells with EC50s of ～0.260 μM
in vivo
AB-423 (30 and 100 mg/kg, p.o. bid) blocks HBV replication in a mouse model of HBV. AB-423 (100 mg/kg, p.o. bid) with entecavir (ETV, 100 ng/mg, qd, p.o.) or 0.1 mg/kg dose of ARB-1467 potently inhibits serum HBV DNA in an HDI model of HBV in immunodeficient NOD-SCID mice[1].
AB-423 Preparation Products And Raw materials
Raw materials
Preparation Products
Global Suppliers ( 69)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4859 | 55 | |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9909 | 65 |
| ShangHai Angti Biotechnology Co., Ltd. | 13764913901 | info@angtibio.com | China | 4976 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Shanghai Chaolan Chemical Technology Center | QQ：65489617 13301690235 | Sales@ATKchemical.com | China | 9711 | 58 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 17801761073 18101056239 | 3193328036@qq.com | China | 28150 | 68 |
| Chuzhou KeMail Chemical Technology Co., Ltd | 0550-5196001 15000891977 | wj520wjxby@126.com | China | 1940 | 55 |
| Twochem Co.Ltd. | 021-58111628 15800915896 | sales@twochem.com | China | 1782 | 58 |
AB-423
CS-2686
AB423;AB-423;AB 423
Benzamide, N-(3,4-difluorophenyl)-2-fluoro-5-[[[(1R)-1-methylpropyl]amino]sulfonyl]-
N-(3,4-Difluorophenyl)-2-fluoro-5-[[[(1R)-1-methylpropyl]amino]sulfonyl]benzamide
AB 423,HBV,AB423,inhibit,Hepatitis B virus,AB-423,Inhibitor
AB-423, 10 mM in DMSO
AB-423 (AB423
5-[[(2R)-butan-2-yl]sulfamoyl]-N-(3,4-difluorophenyl)-2-fluorobenzamide
D-Gluconic acid (solution) (51.205%w/w in water)
1572510-80-5
