5-Methoxysalicylic acid
- CAS No.
- 2612-02-4
- Chemical Name:
- 5-Methoxysalicylic acid
- Synonyms
- 2-HYDROXY-5-METHOXYBENZOIC ACID;5-MeOSA;RARECHEM AL BO 0993;acid5-methoxysalicylic;LABOTEST-BB LT00847979;6-HYDROXY-3-ANISIC ACID;2-hydroxy-m-anisic acid;5-METHOXYSALICYLIC ACID;5-O-METHYL GENTISIC ACID;5-MethoxysalicylicAcid>
- CBNumber:
- CB1466366
- Molecular Formula:
- C8H8O4
- Molecular Weight:
- 168.15
- MDL Number:
- MFCD00002459
- MOL File:
- 2612-02-4.mol
- MSDS File:
- SDS
| Melting point | 141-143 °C(lit.) |
|---|---|
| Boiling point | 217.07°C (rough estimate) |
| Density | 1.1816 (rough estimate) |
| refractive index | 1.4611 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Fine Crystalline Powder |
| pka | 3.01±0.10(Predicted) |
| color | Beige |
| Water Solubility | 1.7 g/L (10 ºC) |
| BRN | 2209647 |
| InChI | 1S/C8H8O4/c1-12-5-2-3-7(9)6(4-5)8(10)11/h2-4,9H,1H3,(H,10,11) |
| InChIKey | IZZIWIAOVZOBLF-UHFFFAOYSA-N |
| SMILES | COc1ccc(O)c(c1)C(O)=O |
| LogP | 2.100 (est) |
| CAS DataBase Reference | 2612-02-4(CAS DataBase Reference) |
| EPA Substance Registry System | Benzoic acid, 2-hydroxy-5-methoxy- (2612-02-4) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29189900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
5-Methoxysalicylic acid price More Price(55)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 146188 | 2-Hydroxy-5-methoxybenzoic acid 98% | 2612-02-4 | 10g | $84.5 | 2026-04-30 | Buy |
| Sigma-Aldrich | 146188 | 2-Hydroxy-5-methoxybenzoic acid 98% | 2612-02-4 | 50g | $416 | 2026-04-30 | Buy |
| TCI Chemical | M1254 | 5-Methoxysalicylic Acid >98.0%(HPLC)(T) | 2612-02-4 | 5g | $52 | 2026-04-30 | Buy |
| TCI Chemical | M1254 | 5-Methoxysalicylic Acid >98.0%(HPLC)(T) | 2612-02-4 | 25g | $149 | 2026-04-30 | Buy |
| TRC | TRC-M264513-500MG | 5-Methoxysalicylic acid | 2612-02-4 | 500mg | $84 | 2026-06-03 | Buy |
5-Methoxysalicylic acid Chemical Properties,Uses,Production
Description
5-Methoxysalicylic acid is a chemical compound belongs to the class of organic compounds known as m-methoxybenzoic acids and derivatives. It is a component of castoreum, the exudate from the castor sacs of the mature beaver.
A mixture of 5-methoxysalicylic acid and spermine can be used as a matrix for oligonucleotides analysis in MALDI mass spectrometry.
It is an isomer of vanillic acid.
2-Hydroxy-5-methoxybenzoic acid is matrix additive which enhances the electrical conductivity of the matrix crystal during matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS).
Chemical Properties
beige fine crystalline powder
Uses
5-Methoxysalicylic acid was used to evaluate MALDI matrix/solvent combinations for intact spore mass spectrometry of Fusarium species.
Uses
2-Hydroxy-5-methoxybenzoic acid was used to evaluate MALDI matrix/solvent combinations for intact spore mass spectrometry of Fusarium species.
Definition
ChEBI:5-methoxysalicylic acid is a methoxysalicylic acid that is salicylic acid which is carrying a methoxy group at position 5. It has a role as a bacterial metabolite and a human urinary metabolite.
Synthesis Reference(s)
Journal of the American Chemical Society, 72, p. 2301, 1950 DOI: 10.1021/ja01161a530
General Description
2-Hydroxy-5-methoxybenzoic acid is matrix additive which enhances the electrical conductivity of the matrix crystal during matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS).
5-Methoxysalicylic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Arbor Chemical Co., Ltd. | 021-60451683 15021268886 | sales@arborchemical.com | China | 765 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shijiazhuang Sdyano Fine Chemical Co., Ltd. | 0311-89250318 13582355795 | master@sjzsdyn.com | China | 2776 | 65 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
View Lastest Price from 5-Methoxysalicylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-11 | 5-Methoxysalicylic acid
2612-02-4
|
$29.00 | 97.38% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-03-20 | 5-Methoxysalicylic acid
2612-02-4
|
1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd | ||
 |
2020-02-01 | 5-Methoxysalicylic acid
2612-02-4
|
$3.00 | 1KG | 98% | 100KG | Career Henan Chemical Co |
-
- 5-Methoxysalicylic acid
2612-02-4
- $29.00
- 97.38%
- TargetMol Chemicals Inc.
-
- 5-Methoxysalicylic acid
2612-02-4
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 5-Methoxysalicylic acid
2612-02-4
- $3.00
- 98%
- Career Henan Chemical Co
