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METHYL 5-METHOXYSALICYLATE

METHYL 5-METHOXYSALICYLATE structure

CAS No.: 2905-82-0

Chemical Name:: METHYL 5-METHOXYSALICYLATE

Synonyms: RARECHEM AL BF 0042;METHYL 5-METHOXYSALICYLATE;Methyl5-Methoxysalicylate>Methyl 5-Methoxy Salicylicate;METHYL 2-HYDROXY-5-METHOXY-BENZOATE;5-METHOXYSALICYLIC ACID METHYL ESTER;2-HYDROXY-5-METHOXYBENZOIC ACID METHYL ESTER;Benzoic acid, 2-hydroxy-5-methoxy-, methyl ester;5-Methoxysalicylic Acid Methyl Ester Methyl 2-Hydroxy-5-methoxybenzoate 2-Hydroxy-5-methoxybenzoic Acid Methyl Ester

CBNumber:: CB6461876

Molecular Formula:: C9H10O4

Molecular Weight:: 182.17

MDL Number:: MFCD00017185

MOL File:: 2905-82-0.mol

MSDS File:: SDS

Last updated:2026-05-28 02:30:40

Product description	Number	Pack Size	Price
Methyl 5-methoxysalicylate 98%	456683	5ml	$89.1
Methyl 5-methoxysalicylate 98%	456683	25ml	$283
Methyl 5-Methoxysalicylate >98.0%(GC)	M2127	5g	$41
Methyl 5-Methoxysalicylate >98.0%(GC)	M2127	25g	$159
Methyl 2-hydroxy-5-methoxybenzoate	FM71188	100g	$150
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METHYL 5-METHOXYSALICYLATE Properties

Boiling point	235-240 °C (lit.)
Density	1.223 g/mL at 25 °C (lit.)
refractive index	n20/D 1.544(lit.)
Flash point	>230 °F
storage temp.	Storage temp. 2-8°C
pka	10.24±0.18(Predicted)
form	clear liquid
color	Colorless to Light yellow
λmax	334nm(CH3CN)(lit.)
InChI	1S/C9H10O4/c1-12-6-3-4-8(10)7(5-6)9(11)13-2/h3-5,10H,1-2H3
InChIKey	DFNBGZODMHWKKK-UHFFFAOYSA-N
SMILES	COC(=O)c1cc(OC)ccc1O
CAS DataBase Reference	2905-82-0(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

WGK Germany

HS Code

2918999090

Storage Class

10 - Combustible liquids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	1
0		0

METHYL 5-METHOXYSALICYLATE price More Price(52)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	456683	Methyl 5-methoxysalicylate 98%	2905-82-0	5ml	$89.1	2023-01-07	Buy
Sigma-Aldrich	456683	Methyl 5-methoxysalicylate 98%	2905-82-0	25ml	$283	2023-01-07	Buy
TCI Chemical	M2127	Methyl 5-Methoxysalicylate >98.0%(GC)	2905-82-0	5g	$41	2026-04-30	Buy
TCI Chemical	M2127	Methyl 5-Methoxysalicylate >98.0%(GC)	2905-82-0	25g	$159	2026-04-30	Buy
Biosynth	FM71188	Methyl 2-hydroxy-5-methoxybenzoate	2905-82-0	100g	$150	2026-06-04	Buy

Product number	Packaging	Price	Buy
456683	5ml	$89.1	Buy
456683	25ml	$283	Buy
M2127	5g	$41	Buy
M2127	25g	$159	Buy
FM71188	100g	$150	Buy

METHYL 5-METHOXYSALICYLATE Chemical Properties,Uses,Production

Synthesis

2612-02-4

74-88-4

2905-82-0

To a solution of N,N-dimethylformamide (80 mL) of 2-hydroxy-5-methoxybenzoic acid (6.0 g, 35.68 mmol) was sequentially added sodium bicarbonate (3.15 g, 37.46 mmol) and iodomethane (2.33 mL, 37.46 mmol). The reaction mixture was stirred at 80 °C for 3 hours. Upon completion of the reaction, ice water was added to the mixture, followed by extraction with ether. The combined organic phases were washed sequentially with water and saturated brine and then dried with anhydrous magnesium sulfate. The solvent was removed by distillation under reduced pressure to give the brown oily product methyl 2-hydroxy-5-methoxybenzoate (5.38 g, 82.8% yield).

References

[1] Patent: US2004/242615, 2004, A1. Location in patent: Page/Page column 13
[2] ChemMedChem, 2016, vol. 11, # 1, p. 108 - 118
[3] Bioorganic and Medicinal Chemistry, 2006, vol. 14, # 2, p. 334 - 343
[4] Organic Letters, 2018, vol. 20, # 5, p. 1316 - 1319

METHYL 5-METHOXYSALICYLATE Preparation Products And Raw materials

Raw materials

5-Methoxysalicylic acid Iodomethane N,N-Dimethylformamide Sodium bicarbonate

Preparation Products

5-METHOXYSALICYLAMIDE

METHYL 5-METHOXYSALICYLATE Suppliers

Global( 131)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29792	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	9976	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52704	58
Aromsyn Co., Ltd.	+86-0571-85585865 +8613336024896	CB@aromsyn.com	China	19183	58
PT CHEM GROUP LIMITED	+86-85511178;	peter68@ptchemgroup.com	China	35425	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Fuxin Pharmaceutical	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Aromsyn Co., Ltd.	58
PT CHEM GROUP LIMITED	58

View Lastest Price from METHYL 5-METHOXYSALICYLATE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-12-26	METHYL 5-METHOXYSALICYLATE 2905-82-0	$1.00	1KG	99%	100KG	Career Henan Chemical Co

METHYL 5-METHOXYSALICYLATE
2905-82-0
$1.00
99%
Career Henan Chemical Co

METHYL 5-METHOXYSALICYLATE Spectrum

METHYL 5-METHOXYSALICYLATE(2905-82-0)¹HNMR METHYL 5-METHOXYSALICYLATE(2905-82-0)IR

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