5-CYANO-2-FLUOROBENZALDEHYDE
- CAS No.
- 146137-79-3
- Chemical Name:
- 5-CYANO-2-FLUOROBENZALDEHYDE
- Synonyms
- Olaparib Impurity 160;3-Cyano-6-fluorobenzaldehyde;5-CYANO-2-FLUOROBENZALDEHYDE;4-FLUORO-3-FORMYL-BENZONITRILE;Benzonitrile, 4-fluoro-3-forMyl-;5-cyanobenzyl-2-fluorobenzaldehyde;Benzonitrile, 4-fluoro-3-formyl- (9CI);5-CYANO-2-FLUOROBENZALDEHYDE ISO 9001：2015 REACH
- CBNumber:
- CB1474714
- Molecular Formula:
- C8H4FNO
- Molecular Weight:
- 149.12
- MDL Number:
- MFCD04974126
- MOL File:
- 146137-79-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 5-Cyano-2-fluorobenzaldehyde Asreported | 269854 | 500mg | $333 |
| 5-Cyano-2-fluorobenzaldehyde Asreported | 269854 | 1g | $463 |
| 5-Cyano-2-fluorobenzaldehyde Asreported | 269854 | 2g | $622 |
| 5-Cyano-2-fluorobenzaldehyde Asreported | 269854 | 5g | $981 |
| 5-Cyano-2-fluorobenzaldehyde Asreported | 269854 | 10g | $1363 |
| More product size | |||
| Boiling point | 216.5±20.0 °C(Predicted) |
|---|---|
| Density | 1.25±0.1 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | solid |
| color | Light yellow to yellow |
| CAS DataBase Reference | 146137-79-3(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P280-P305+P351+P338-P310 |
| HazardClass | IRRITANT |
| HS Code | 2926907090 |
5-CYANO-2-FLUOROBENZALDEHYDE price More Price(67)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 269854 | 5-Cyano-2-fluorobenzaldehyde Asreported | 146137-79-3 | 500mg | $333 | 2026-06-03 | Buy |
| Usbiological | 269854 | 5-Cyano-2-fluorobenzaldehyde Asreported | 146137-79-3 | 1g | $463 | 2026-06-03 | Buy |
| Usbiological | 269854 | 5-Cyano-2-fluorobenzaldehyde Asreported | 146137-79-3 | 2g | $622 | 2026-06-03 | Buy |
| Usbiological | 269854 | 5-Cyano-2-fluorobenzaldehyde Asreported | 146137-79-3 | 5g | $981 | 2026-06-03 | Buy |
| Usbiological | 269854 | 5-Cyano-2-fluorobenzaldehyde Asreported | 146137-79-3 | 10g | $1363 | 2026-06-03 | Buy |
5-CYANO-2-FLUOROBENZALDEHYDE Chemical Properties,Uses,Production
Synthesis
1194-02-1
146137-79-3
The general procedure for the synthesis of 4-fluoro-3-formylbenzonitrile from p-fluorobenzonitrile is as follows: Example 112 Synthesis of 2-fluoro-5-cyanobenzaldehyde To a stirred solution of cooled diisopropylamine (15.4 mL, 0.11 mol) in anhydrous tetrahydrofuran (200 mL) under argon protection, n-butyllithium (40 mL, 2.5 M hexane solution, 0.11 mol) was slowly added through a dropping funnel over a period of 30 minutes, keeping the reaction temperature at 0°C. The mixture was continued to be stirred at this temperature for 30 minutes. Subsequently, the reaction system was cooled to -78 °C. A solution of anhydrous tetrahydrofuran (50 mL) of 4-fluorobenzonitrile (12.1 g, 0.1 mol) was added dropwise over 15 minutes. The reaction mixture was stirred at -78 °C for 1 h via syringe. Then, dimethylformamide (8 mL) was added dropwise and stirring was continued at -78 °C for 20 min. The reaction was quenched by rapid addition of acetic acid (20 mL) followed by water (500 mL). The product was extracted with ether (2 x 500 mL). The combined organic layers were washed sequentially with 1N HCl, water and saturated sodium chloride solution and then dried with anhydrous magnesium sulfate. After evaporation of the solvent, 2-fluoro-5-cyanobenzaldehyde (11.8 g, 79% yield) was obtained as a light yellow solid. 1H NMR (CDCl3): δ 10.32 (s, 1H), 8.18 (dd, 1H, J = 6.5, 2.5 Hz), 7.88 (m, 1H), 7.33 (t, 1H, J = 9.5 Hz).
References
[1] Patent: US6221914, 2001, B1
[2] Patent: US2002/103229, 2002, A1
[3] Patent: US2004/127536, 2004, A1
[4] Patent: US2005/9876, 2005, A1
5-CYANO-2-FLUOROBENZALDEHYDE Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hefei Lbao Physical & Chemical Science Co.,Ltd | +1-5184799099; | lbaochemicals@gmail.com | China | 670 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32997 | 60 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29780 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569262 +86-15003564040 | 1056@dideu.com | China | 3969 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 | contact@fuxinpharm.com | China | 9976 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21135 | 58 |
View Lastest Price from 5-CYANO-2-FLUOROBENZALDEHYDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-30 | 5-CYANO-2-FLUOROBENZALDEHYDE
146137-79-3
|
1kg | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2026-05-18 | 5-CYANO-2-FLUOROBENZALDEHYDE
146137-79-3
|
1kg | 98% | Hefei Lbao Physical & Chemical Science Co.,Ltd | |||
 |
2026-02-02 | 4-Fluoro-3-formylbenzonitrile
146137-79-3
|
10mg | 99%HPLC | 2000tons | Shaanxi Dideu Medichem Co. Ltd |
-
- 5-CYANO-2-FLUOROBENZALDEHYDE
146137-79-3
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- 5-CYANO-2-FLUOROBENZALDEHYDE
146137-79-3
- $0.00
- 98%
- Hefei Lbao Physical & Chemical Science Co.,Ltd
-
- 4-Fluoro-3-formylbenzonitrile
146137-79-3
- 99%HPLC
- Shaanxi Dideu Medichem Co. Ltd
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