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Elenbecestat

CAS No.
1388149-39-0
Chemical Name:
Elenbecestat
Synonyms
Elenbecestat free base;2-Pyrazinecarboxamide, N-[3-[(4aS,5S,7aS)-2-amino-4a,5-dihydro-5-(trifluoromethyl)-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl]-4-fluorophenyl]-5-(difluoromethyl)-
CBNumber:
CB14844751
Molecular Formula:
C19H15F6N5O2S
Molecular Weight:
491.41
MDL Number:
MOL File:
1388149-39-0.mol
MSDS File:
SDS
Last updated:2026-05-11 16:31:51

Elenbecestat Properties

solubility Soluble in DMSO:80.0(Max Conc. mg/mL);182.88(Max Conc. mM)

Elenbecestat price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth NFC14939 Elenbecestat 1388149-39-0 10mg $776.2 2026-06-04 Buy
Biosynth NFC14939 Elenbecestat 1388149-39-0 25mg $1455.5 2026-06-04 Buy
Biosynth NFC14939 Elenbecestat 1388149-39-0 50mg $2328.5 2026-06-04 Buy
Product number Packaging Price Buy
NFC14939 10mg $776.2 Buy
NFC14939 25mg $1455.5 Buy
NFC14939 50mg $2328.5 Buy

Elenbecestat Chemical Properties, Uses, Production

Description

Elenbecestat,also known as E2609 is a BACE1 inhibitor. By inhibiting BACE, a key enzyme in the production of Aβ peptides, E2609 decreases the formation of these peptides which can aggregate into toxic oligomers and protofibrils and eventually form amyloid plaques in the brain. Elenbecestat has been shown to reduce Aβ levels in cerebrospinal fluid, was investigated in two global phase 3 studies in early AD.

Uses

BACE-IN-3 (Example 3) is a BACE inhibitor, with an IC50 of 0.004 μM[1].

References

[1] Adrian Hall, et al. Dérivés d'aminodihydrothiazine condensés utiles en tant qu'inhibiteurs de bace. Patent WO2012098213A1.

Elenbecestat Preparation Products And Raw materials

Raw materials

Preparation Products

Elenbecestat Suppliers

Global Suppliers ( 5)
Supplier Tel Email Country ProdList Advantage
HANGZHOU CLAP TECHNOLOGY CO.,LTD 86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6288 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 cindy.huang@synzest.com China 11975 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58

View Latest Price from Elenbecestat manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Elenbecestat free base pictures 2026-05-11 Elenbecestat free base
1388149-39-0
$2720.00-4900.00 10g TargetMol Chemicals Inc.
2-Pyrazinecarboxamide, N-[3-[(4aS,5S,7aS)-2-amino-4a,5-dihydro-5-(trifluoromethyl)-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl]-4-fluorophenyl]-5-(difluoromethyl)- Elenbecestat free base 1388149-39-0 C19H15F6N5O2S