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TIQ-A

CAS No.
420849-22-5
Chemical Name:
TIQ-A
Synonyms
TIQ-A, 10 mM in DMSO;Thieno[2,3-c]isoquinolin-5(4H)-one;TIQ-A,poly ADP ribose polymerase,ADP-ribosyltransferase,TIQA,Inhibitor,PARP,TIQ A,inhibit,tankyrases,ADP-ribosylation,poly-ART
CBNumber:
CB1504888
Molecular Formula:
C11H7NOS
Molecular Weight:
201.24
MDL Number:
MFCD06407947
MOL File:
420849-22-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 23:41:55

TIQ-A Properties

Melting point 256-258°C
Boiling point 282.2±9.0 °C(Predicted)
Density 1.358±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: 16 mg/mL, soluble
form solid
pka 13.04±0.20(Predicted)
color Light green to green

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H312-H332
Precautionary statements  P280
Hazard Codes  Xn
Risk Statements  20/21/22
WGK Germany  3
NFPA 704
0
3 0

TIQ-A price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T2825 TIQ-A ≥98% (HPLC), solid 420849-22-5 1mg $109 2022-05-15 Buy
Sigma-Aldrich T2825 TIQ-A ≥98% (HPLC), solid 420849-22-5 5mg $365 2022-05-15 Buy
Cayman Chemical 16112 TIQ-A ≥98% 420849-22-5 500μg $36 2026-04-30 Buy
Cayman Chemical 16112 TIQ-A ≥98% 420849-22-5 1mg $63 2026-04-30 Buy
Cayman Chemical 16112 TIQ-A ≥98% 420849-22-5 5mg $253 2026-04-30 Buy
Product number Packaging Price Buy
T2825 1mg $109 Buy
T2825 5mg $365 Buy
16112 500μg $36 Buy
16112 1mg $63 Buy
16112 5mg $253 Buy

TIQ-A Chemical Properties,Uses,Production

Chemical Properties

Dark Brown Solid

Uses

A cell permeable, potent PARP inhibitor with an IC50 of 450nM. Shown to be neuroprotective against oxygen-glucose deprivation injury in vitro in cultured murine cortical cells ( IC50 of 150nM) and in vivi in rat transient focal ischemia model (3 mg/kg ip).

IC 50

TNKS2: 24 nM (IC50); PARP2: 210 nM (IC50); PARP15: 230 nM (IC50); PARP10: >10 μM (IC50); PARP14: >10 μM (IC50)

TIQ-A Preparation Products And Raw materials

Raw materials

Preparation Products

TIQ-A Suppliers

Global( 34)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
BOC Sciences 16314854226 info@bocsci.com United States 9909 65
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 sales@rrkchem.com China 57336 58
Career Henan Chemica Co +86-0371-86658258 +86-13203830695 laboratory@coreychem.com China 30203 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Taizhou Nanfeng Pharmaceutical Research Institute nanfengpharma@126.co 18616377689 nanfengpharma@126.com China 20008 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8137 58

TIQ-A Spectrum

Thieno[2,3-c]isoquinolin-5(4H)-one TIQ-A,poly ADP ribose polymerase,ADP-ribosyltransferase,TIQA,Inhibitor,PARP,TIQ A,inhibit,tankyrases,ADP-ribosylation,poly-ART TIQ-A, 10 mM in DMSO 420849-22-5 Inhibitors