Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>2,3,4,5-Tetrahydro-1H-benzo[d]azepine

2,3,4,5-Tetrahydro-1H-benzo[d]azepine

2,3,4,5-Tetrahydro-1H-benzo[d]azepine Structure
2,3,4,5-Tetrahydro-1H-benzo[d]azepine structure
CAS No.
4424-20-8
Chemical Name:
2,3,4,5-Tetrahydro-1H-benzo[d]azepine
Synonyms
AKOS BB-9904;BENZ-3-AZEPINE;5-Azabenzocycloheptene;2,3,4,5-Tetrahydro-1H-3-benzazepine;1,2,4,5-tetrahydro-3H-3-benzoazepine;1,2,4,5-Tetrahydro-3H-benzo[d]azepine;1H-3-Benzazepine, 2,3,4,5-tetrahydro-;2,3,4,5-Tetrahydro-1H-benzo[d]azepine;2,3,4,5-Tetrahydro-1H-Benzo [D] Azazene;2,3,4,5-Tetrahydro-1H-benzo[d]azepine 90+%
CBNumber:
CB1684937
Molecular Formula:
C10H13N
Molecular Weight:
147.22
MDL Number:
MFCD04012620
MOL File:
4424-20-8.mol
Last updated:2026-09-12 18:49:20
Request For Quotation

2,3,4,5-Tetrahydro-1H-benzo[d]azepine Properties

Boiling point 110-120℃ (11 Torr)
Density 0.981±0.06 g/cm3 (20 ºC 760 Torr)
refractive index 1.565 (589.3 nm 20℃)
Flash point 114.9±14.2℃
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form liquid
pka 10.27±0.20(Predicted)
color Clear, brown
InChI InChI=1S/C10H13N/c1-2-4-10-6-8-11-7-5-9(10)3-1/h1-4,11H,5-8H2
InChIKey MWVMYAWMFTVYED-UHFFFAOYSA-N
SMILES N1CCC2=CC=CC=C2CC1
CAS DataBase Reference 4424-20-8

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)
GHS05
Signal word  Danger
Hazard statements  H314-H318
Precautionary statements  P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P321-P363-P405-P501
Hazard Codes  Xi
Risk Statements  20/21/22-34
Safety Statements  23-26-36/37/39-45
HazardClass  IRRITANT
HS Code  29339900

2,3,4,5-Tetrahydro-1H-benzo[d]azepine price More Price(53)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 435028 5-Azabenzocycloheptene 4424-20-8 100mg $319 2026-06-03 Buy
Usbiological 435028 5-Azabenzocycloheptene 4424-20-8 500mg $496 2026-06-03 Buy
TRC TRC-A795190-500MG 5-Azabenzocycloheptene 4424-20-8 500mg $179 2026-06-03 Buy
TRC TRC-A795190-1G 5-Azabenzocycloheptene 4424-20-8 1g $278 2026-06-03 Buy
TRC TRC-A795190-100MG 5-Azabenzocycloheptene 4424-20-8 100mg $72 2026-06-03 Buy
Product number Packaging Price Buy
435028 100mg $319 Buy
435028 500mg $496 Buy
TRC-A795190-500MG 500mg $179 Buy
TRC-A795190-1G 1g $278 Buy
TRC-A795190-100MG 100mg $72 Buy

2,3,4,5-Tetrahydro-1H-benzo[d]azepine Chemical Properties, Uses, Production

Synthesis

1,2-Phenylacetonitrile was dissolved in 150 mL of DMF, and 15.86 g (142 mmol) of potassium tert-butoxide was added at an internal temperature of -10 to 0 °C. The mixture was stirred at 0–5 °C for 2 h. Then, 200 mL of water and 22 mL of 30% hydrochloric acid were added at 0–5 °C, and the mixture was stirred for 1 h. The mixture was filtered to obtain a crude product, which was then dissolved in 170 mL of methanol and recrystallized. After filtration and drying, 20.87 g of 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINE was obtained, with a yield of 89%.

Uses

5-Azabenzocycloheptene is a reactant used in the synthesis of nonretinoid retinol binding protein 4 antagonists for potential treatment of atrophic age-related macular degeneration and Stargardt disease.

2,3,4,5-Tetrahydro-1H-benzo[d]azepine synthesis

130800-04-3
4424-20-8
Synthesis of 2,3,4,5-Tetrahydro-1H-benzo[d]azepine from 1,2-phenylenebis(ethane-2,1-diyl) diMethanesulfonate

2,3,4,5-Tetrahydro-1H-benzo[d]azepine Preparation Products And Raw materials

Raw materials

1,2-BenzenediethanaMine 1,2,4,5-Tetrahydrobenzo[d]azepine-3-carbaldehyde 4,5-Dihydro-1H-benzo[d]azepin-2(3H)-one 1,2-phenylenebis(ethane-2,1-diyl) diMethanesulfonate 1,2-Bis(cyanomethyl)benzene
2-[2-(2-hydroxyethyl)phenyl]ethanol 1,2-Phenylenediacetic acid Ethanol Ammonia 2-PhenylethylaMine

1of2

Preparation Products

GSK J4 HCl

2,3,4,5-Tetrahydro-1H-benzo[d]azepine Suppliers

Global Suppliers ( 130)
Supplier Tel Email Country ProdList Advantage
Suzhou Nuobeike Biological Technology Co., Ltd. 13962527677 1551481742@qq.com China 297 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16305 64
Shanghai Sphchem Co., Ltd. 021-56491756 13512199871 2819742715@qq.com China 3994 55
Thermo Fisher Scientific 800-810-5118 cnchemical@thermofisher.com China 17752 75
Nanjing JinruiJiuAn Biotechnology Co., Ltd. 025-58196018 800028039 sales@fartop.net China 2227 55
Shanghai Topbiochem Technology Co., Ltd 021-58170097 info@topbiochem.com China 9509 58
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 22497 55
Shanghai Raise Chemical Technology Co.,Ltd +86-021-50935922 China 7854 55
Supplier Advantage
Suzhou Nuobeike Biological Technology Co., Ltd. 58
J & K SCIENTIFIC LTD. 76
Jia Xing Isenchem Co.,Ltd 66
Nanjing Chemlin Chemical Co., Ltd 64
Shanghai Sphchem Co., Ltd. 55
Thermo Fisher Scientific 75
Nanjing JinruiJiuAn Biotechnology Co., Ltd. 55
Shanghai Topbiochem Technology Co., Ltd 58
9ding chemical ( Shanghai) Limited 55
Shanghai Raise Chemical Technology Co.,Ltd 55

View Latest Price from 2,3,4,5-Tetrahydro-1H-benzo[d]azepine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINE pictures 2021-07-02 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINE
4424-20-8
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINE pictures 2019-07-10 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINE
4424-20-8
 $1.00 1KG 98% 150KG Career Henan Chemical Co

2,3,4,5-Tetrahydro-1H-benzo[d]azepine Spectrum

2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINE(4424-20-8)1HNMR

4424-20-8 (2,3,4,5-Tetrahydro-1H-benzo[d]azepine) Related Search:

2,3,4,5-Tetrahydro-1H-benzo[b]azepine RHOEADINE CEPHALOTAXINE HARRINGTONINE R-(-)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine, hydrochloride
2-phenyl-4-azabicyclo[5.4.0]undeca-7,9,11-triene-9,10-diol 1,3,4,5-TETRAHYDRO-5-OXA-BENZO[B]AZEPINE (+/-)-6-Chloro-7,8-dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide SCH 23390, [N-methyl-3H] (+/-)-7,8-Dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide
7-Chloro-2,3,4,5-tetrahydro-1H-benzo[b]azepine hydrochloride (+/-)-6-Chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide R(+)-6-bromo-7,8-dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide 8-Fluoro-2,3,4,5-tetrahydro-1H-benzo[b]azepine hydrochloride 8-Chloro-2,3,4,5-tetrahydro-5-phenyl-1H-3-benzazepin-7-ol-(5R)
8-Methoxy-2,3,4,5-tetrahydro-1H-benzo[c]azepine S(-)-SCH-23388 nor methyl- HCl 4,5-Dihydro-1H-benzo[d]azepin-2(3H)-one

1of4

AKOS BB-9904 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINE HYDROCHLORIDE 2,3,4,5-Tetrahydro-1H-3-benzazepine BENZ-3-AZEPINE 1H-3-Benzazepine, 2,3,4,5-tetrahydro- 1,2,4,5-Tetrahydro-3H-benzo[d]azepine 1,2,4,5-tetrahydro-3H-3-benzoazepine 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINE BENZ-3-AZEPINE 2,3,4,5-Tetrahydro-1H-benzo[d]azepinemin.90% 5-Azabenzocycloheptene 2,3,4,5-Tetrahydro-1H-benzo[d]azepine 90+% high quality 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINE 2,3,4,5-Tetrahydro-1H-Benzo [D] Azazene 2,3,4,5-tetrahydro-1H-3-benzazepine - [T23699] 2,3,4,5-Tetrahydro-1H-benzo[d]azepine 4424-20-8