Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>2,5-BIS-BENZYLOXY-BENZOIC ACID

2,5-BIS-BENZYLOXY-BENZOIC ACID

2,5-BIS-BENZYLOXY-BENZOIC ACID Structure
2,5-BIS-BENZYLOXY-BENZOIC ACID structure
CAS No.
67127-91-7
Chemical Name:
2,5-BIS-BENZYLOXY-BENZOIC ACID
Synonyms
2,5-BIS-BENZYLOXY-BENZOIC ACID;Benzoic acid, 2,5-bis(phenylmethoxy)-
CBNumber:
CB1703915
Molecular Formula:
C21H18O4
Molecular Weight:
334.37
MDL Number:
MFCD00156981
MOL File:
67127-91-7.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:51
Product description Number Pack Size Price
2,5-Bis(benzyloxy)benzoicacid 0322AC 1g $264
2,5-BIS-BENZYLOXY-BENZOIC ACID 95.00% CHM0019640 1G $1000.52
2,5-Bis(benzyloxy)benzoicacid 0322AC 25g $1776
2,5-Bis(benzyloxy)benzoicacid 98% A111500 25g $1116
2,5-BIS-BENZYLOXY-BENZOICACID 96% 37445 25/ G $1260
Request For Quotation

2,5-BIS-BENZYLOXY-BENZOIC ACID Properties

storage temp. Sealed in dry,Room Temperature

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338

2,5-BIS-BENZYLOXY-BENZOIC ACID price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AK Scientific 0322AC 2,5-Bis(benzyloxy)benzoicacid 67127-91-7 1g $264 2021-12-16 Buy
American Custom Chemicals Corporation CHM0019640 2,5-BIS-BENZYLOXY-BENZOIC ACID 95.00% 67127-91-7 1G $1000.52 2021-12-16 Buy
AK Scientific 0322AC 2,5-Bis(benzyloxy)benzoicacid 67127-91-7 25g $1776 2021-12-16 Buy
Ambeed A111500 2,5-Bis(benzyloxy)benzoicacid 98% 67127-91-7 25g $1116 2021-12-16 Buy
AstaTech 37445 2,5-BIS-BENZYLOXY-BENZOICACID 96% 67127-91-7 25/ G $1260 2021-12-16 Buy
Product number Packaging Price Buy
0322AC 1g $264 Buy
CHM0019640 1G $1000.52 Buy
0322AC 25g $1776 Buy
A111500 25g $1116 Buy
37445 25/ G $1260 Buy

2,5-BIS-BENZYLOXY-BENZOIC ACID Chemical Properties,Uses,Production

Synthesis

Benzoic acid, 2,5-bis(phenylmethoxy)-, phenylmethyl ester

78283-37-1

2,5-BIS-BENZYLOXY-BENZOIC ACID

67127-91-7

General procedure for the synthesis of 2,5-bis-benzyloxybenzoic acid from the compound (CAS: 78283-37-1): 1.0 g (2.4 mmol) of the ester 25 and 0.19 g (4.7 mmol) of sodium hydroxide were dissolved in 15 mL of a solvent mixture of methanol, dioxane, and water (1:1:1, v/v), and stirred at reflux for 14 hours. After completion of the reaction, it was cooled to 25 °C and most of the organic solvent was removed by rotary evaporator. The residue was diluted with water, acidified with 1N HCl to pH < 7 and subsequently extracted twice with ethyl acetate (50 mL). The organic phases were combined, washed sequentially with water and saturated saline, dried over anhydrous magnesium sulfate, and concentrated. The crude product was purified by column chromatography using hexane and ethyl acetate (1:1, v/v) as eluents to afford 0.72 g (91% yield) of the target compound 13.1H NMR (δ, ppm): 11.06 (s, 1H), 7.81 (d, J = 3.1 Hz, 1H), 7.43-7.32 (m, 10H), 7.17 (dd, J = 9.0, 3.1 Hz, 1H), 7.07 (d, J = 9.0 Hz, 1H), 5.26 (s, 2H), 5.08 (s, 2H); 13C NMR (δ, ppm): 165.3, 153.9, 151.9, 136.6, 134.6, 129.4, 129.4, 128.8, 128.4, 128.2, 127.8, 123.0, 119.0, 117.8, 115.1, 73.2, 70.9.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 1, p. 353 - 356
[2] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981, p. 2570 - 2576
[3] Journal of Organic Chemistry, 2004, vol. 69, # 10, p. 3530 - 3537

2,5-BIS-BENZYLOXY-BENZOIC ACID synthesis

78283-37-1
67127-91-7
Synthesis of 2,5-BIS-BENZYLOXY-BENZOIC ACID from Benzoic acid, 2,5-bis(phenylmethoxy)-, phenylmethyl ester

2,5-BIS-BENZYLOXY-BENZOIC ACID Preparation Products And Raw materials

Raw materials

Benzoic acid, 2,5-bis(phenylmethoxy)-, phenylmethyl ester methyl 2,5-bis(benzyloxy)benzoate 1,4-Dioxane Methanol Sodium hydroxide
Water

1of2

Preparation Products

2,5-BIS-BENZYLOXY-BENZOIC ACID Suppliers

Global( 51)Suppliers
Supplier Tel Email Country ProdList Advantage
Wuhan Chemwish Technology Co., Ltd 		027-67849912 sales@chemwish.com CHINA 10821 58
Hunan Jibang Biological Technology Co., LTD 		+8613776644403 sales02@kingboomtech.com China 1804 58
Aromsyn Co., Ltd. 		+86-0571-85585865 +8613336024896 CB@aromsyn.com China 19183 58
Aladdin Scientific 		tp@aladdinsci.com United States 52923 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. +86-21-54098501 sales@sinch.com.cn China 11598 64
J & K SCIENTIFIC LTD. 18210857532; 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40228 62
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35896 56
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42934 64
Supplier Advantage
Wuhan Chemwish Technology Co., Ltd 		58
Hunan Jibang Biological Technology Co., LTD 		58
Aromsyn Co., Ltd. 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. 64
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Wuhan Chemwish Technology Co., Ltd 56
Shanghai Hanhong Scientific Co.,Ltd. 64

67127-91-7(2,5-BIS-BENZYLOXY-BENZOIC ACID)Related Search:

2-BENZYLOXYBENZOIC ACID 5-Methoxysalicylic acid 3-Benzyloxybenzaldehyde 2,5-DIMETHOXYBENZYL ALCOHOL 1,4-Dibenzyloxybenzene
2,5-Dihydroxybenzoic acid 2-Ethoxybenzoic acid 2,5-Dimethoxybenzoic acid 3-BENZYLOXYBENZYL ALCOHOL 3,5-BIS(BENZYLOXY)BENZOIC ACID METHYL ESTER
3,4-BIS(BENZYLOXY)BENZOIC ACID 3,5-BIS(BENZYLOXY)BENZOIC ACID 3,5-BIS(BENZYLOXY)BENZOIC ACID METHYL ESTER 2-BENZYLOXYBENZYL ALCOHOL 3-BENZYLOXYBENZOIC ACID
2,5-DI(4-BUTYLOXYBENZYLOXY)BENZOIC ACID 3-HYDROXY-6-METHOXYBENZOIC ACID 2 5-DIETHOXYBENZOIC ACID 97

1of4

2,5-BIS-BENZYLOXY-BENZOIC ACID Benzoic acid, 2,5-bis(phenylmethoxy)- 67127-91-7 C21H18O4