ChemicalBook >> CAS DataBase List >>13,14-Dihydroprostaglandin E1

13,14-Dihydroprostaglandin E1

CAS No.
58962-34-8
Chemical Name:
13,14-Dihydroprostaglandin E1
Synonyms
6-Keto Prostaglandin;6-KETOPROSTAGLANDIN F1A;6-Oxo-prostaglandin F1α;6-oxo-prostaglandin F1alpha;KFGOFTHODYBSGM-ZUNNJUQCSA-N;6-Keto-PGF1alpha;6-KETO-PROSTAGLANDIN F1ALPHA;6-Keto-Prostaglandin F1-alfa;PROSTAGLANDIN F1-ALPHA, 6-KETO-;Epoprostenol Related CoMpound A
CBNumber:
CB1721856
Molecular Formula:
C20H34O6
Molecular Weight:
370.48
MDL Number:
MFCD00135222
MOL File:
58962-34-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:50:04

13,14-Dihydroprostaglandin E1 Properties

Boiling point 575.3±50.0 °C(Predicted)
Density 1.191±0.06 g/cm3(Predicted)
RTECS UK8428300
storage temp. −20°C
solubility ethanol: 10 mg/mL, clear, faintly yellow
pka 4.69±0.10(Predicted)
form White to off-white solid.
color White to off-white
BRN 2821925
Major Application pharmaceutical (small molecule)
InChIKey KFGOFTHODYBSGM-DFOLFLIJSA-N
SMILES CCCCCC(O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1CC(=O)CCCCC(O)=O
FDA UNII 8URB805JJJ
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H317
Precautionary statements  P261-P280g-P302+P352a-P321-P333+P313-P501a
Safety Statements  22-24/25
WGK Germany  3
8-10
HS Code  2937909000
Storage Class 11 - Combustible Solids
NFPA 704
0
3 0

13,14-Dihydroprostaglandin E1 price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 1237611 Epoprostenol Related Compound A United States Pharmacopeia (USP) Reference Standard 58962-34-8 15mg $1450 2026-04-30 Buy
Cayman Chemical 15210 6-keto Prostaglandin F1α ≥98% 58962-34-8 1mg $107 2026-04-30 Buy
Cayman Chemical 15210 6-keto Prostaglandin F1α ≥98% 58962-34-8 5mg $396 2026-04-30 Buy
Cayman Chemical 15210 6-keto Prostaglandin F1α ≥98% 58962-34-8 10mg $740 2026-04-30 Buy
TRC TRC-K202040-5MG 6-Ketoprostaglandin F1alpha 58962-34-8 5mg $2327 2026-06-03 Buy
Product number Packaging Price Buy
1237611 15mg $1450 Buy
15210 1mg $107 Buy
15210 5mg $396 Buy
15210 10mg $740 Buy
TRC-K202040-5MG 5mg $2327 Buy

13,14-Dihydroprostaglandin E1 Chemical Properties, Uses, Production

Description

6-keto prostaglandin F (6-keto PGF) is the inactive, non-enzymatic hydrolysis product of PGI2. 6-keto PGF serves as a useful marker of PGI2 biosynthesis in vivo. When [3H]-PGI2 is injected into healthy human males, 6.6% of the radioactivity is recovered from urine as [3H]-6-keto PGF.

Uses

6-Ketoprostaglandin F1α is the stable hydrolysis product of prostacyclin (P839060), an eicosanoid which prevents the formation of platelet plugs and an effective vasodilator.

Definition

ChEBI: A prostaglandin Falpha that is prostaglandin F1alpha bearing a keto substituent at the 6-position.

IC 50

Human Endogenous Metabolite

References

[1] PACE-ASCIAK C. Isolation, structure, and biosynthesis of 6-ketoprostaglandin F1.alpha. in the rat stomach[J]. Journal of the American Chemical Society, 1976, 98 8: 2348-2349. DOI: 10.1021/ja00424a065
[2] ROY A. JOHNSON. The chemical structure of prostaglandin X (prostacyclin)[J]. Prostaglandins, 1976, 12 6: Pages 915-928. DOI: 10.1016/0090-6980(76)90126-x
[3] A R BRASH. Metabolic disposition of prostacyclin in humans.[J]. Journal of Pharmacology and Experimental Therapeutics, 1983, 226 1: 78-87.
[4] MALARVIZHI GURUSAMY. Inhibition of microsomal prostaglandin E synthase-1 ameliorates acute lung injury in mice.[J]. Journal of Translational Medicine, 2021: 340. DOI: 10.1186/s12967-021-03016-9

13,14-Dihydroprostaglandin E1 Preparation Products And Raw materials

Raw materials

Preparation Products

13,14-Dihydroprostaglandin E1 Suppliers

Global Suppliers ( 45)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 sales@rrkchem.com China 57336 58
Career Henan Chemica Co +86-0371-86658258 +86-13203830695 laboratory@coreychem.com China 30203 58
Meng Cheng Technology (Shanghai) Co., LTD 400-820-6829 sales@mitachieve.com China 8857 58
Shanghai Universal Biotech Co.,Ltd 15921930842 15921930842 yh-wang@univ-bio.com China 25030 58
amyjet 4006800868;027-59626688 18771149750 sales@amyjet.com China 2909 58
Hubei Aiputi Bioengineering Co., Ltd. 17762444226 d17762444226@163.com China 2400 58
PROSTAGLANDIN F1-ALPHA, 6-KETO- 6-KETO-PROSTAGLANDIN F1ALPHA 6-OXO-9ALPHA,11ALPHA,15S-TRIHYDROXY-PROST-13E-EN-1-OIC ACID 6-KETOPROSTAGLANDIN F1A 6-keto Prostaglandin F1α Lipid Maps MS Standard Epoprostenol Related CoMpound A (9α,11α,13e,15s)-9,11,15-trihydroxy-6-oxoprosta-13-en-1-oic acid 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]-6-oxoheptanoic acid 6-KETO-PROSTAGLANDIN F1ALPHA EIA STANDARD 6-Oxo-prostaglandin F1α, (9α,11α,13E,15S)-9,11,15-Trihydroxy-6-oxoprosta-13-en-1-oic acid 6-Keto Prostaglandin 6-Oxo-prostaglandin F1α 6-oxo-prostaglandin F1alpha KFGOFTHODYBSGM-ZUNNJUQCSA-N 6-keto Prostaglandin F1 MaxSpecStandard (9alpha,11alpha,13E,15S)-9,11,15-Trihydroxy-6-oxoprost-13-en-1-oic acid 6-Keto-PGF1alpha 6-Ketoprostaglandin F1alpha 6-Keto-Prostaglandin F1-alfa 6-Keto-Prostaglandin F1-alfa-d5 Prost-13-en-1-oic acid, 9,11,15-trihydroxy-6-oxo-, (9α,11α,13E,15S)- 6-keto Prostaglandin F1α MaxSpec? Standard Epoprostenol Related Compound A (7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(S,E)-3-hydroxyoct-1-enyl]cyclop (1237611) 6-keto Prostaglandin F1α Lipid Maps? MS Standard 58962-34-8 58962-34-2