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4-HYDROXYPHENOXYACETIC ACID

CAS No.
1878-84-8
Chemical Name:
4-HYDROXYPHENOXYACETIC ACID
Synonyms
4-HYDROXYPHENOXYACETIC ACID;(4-hydroxyphenoxy)-aceticaci;2-(4-hydroxyphenoxy)aceticaci;(P-HYDROXYPHENOXY)ACETIC ACID;2-(4-Hydroxyphenoxy)acetic acid;4-Hydroxyphenoxyacetic acid, 98+%;Acetic acid, 2-(4-hydroxyphenoxy)-;2-(4-Hydroxyphenoxy)ethanoic acid, 4-(Carboxymethoxy)phenol
CBNumber:
CB1760189
Molecular Formula:
C8H8O4
Molecular Weight:
168.15
MDL Number:
MFCD00014362
MOL File:
1878-84-8.mol
MSDS File:
SDS
Last updated:2026-05-27 23:45:42
Product description Number Pack Size Price
(4-Hydroxyphenoxy)acetic acid 98% 439398 5g $54.8
(4-Hydroxyphenoxy)acetic Acid >99.0%(T) H0992 5g $75
(4-Hydroxyphenoxy)acetic Acid >99.0%(T) H0992 25g $243
2-(4-Hydroxyphenoxy)acetic Acid TRC-H801505-250MG 250mg $63
2-(4-Hydroxyphenoxy)acetic Acid TRC-H801505-2.5G 2.5g $120

4-HYDROXYPHENOXYACETIC ACID Properties

Melting point 154-157 °C (lit.)
Boiling point 372.6±17.0 °C(Predicted)
Density 1.367±0.06 g/cm3(Predicted)
storage temp. RT, stored under nitrogen
solubility soluble in Methanol
form Fine Crystalline Powder
pka 3.27±0.10(Predicted)
color Off-white to beige
BRN 1952779
InChI 1S/C8H8O4/c9-6-1-3-7(4-2-6)12-5-8(10)11/h1-4,9H,5H2,(H,10,11)
InChIKey PKGWLCZTTHWKIZ-UHFFFAOYSA-N
SMILES OC(=O)COc1ccc(O)cc1
LogP 0.650
CAS DataBase Reference 1878-84-8(CAS DataBase Reference)
EPA Substance Registry System Acetic acid, (4-hydroxyphenoxy)- (1878-84-8)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
TSCA  TSCA listed
HS Code  29189990
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
0
2 0

4-HYDROXYPHENOXYACETIC ACID price More Price(40)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 439398 (4-Hydroxyphenoxy)acetic acid 98% 1878-84-8 5g $54.8 2026-04-30 Buy
TCI Chemical H0992 (4-Hydroxyphenoxy)acetic Acid >99.0%(T) 1878-84-8 5g $75 2026-04-30 Buy
TCI Chemical H0992 (4-Hydroxyphenoxy)acetic Acid >99.0%(T) 1878-84-8 25g $243 2026-04-30 Buy
TRC TRC-H801505-250MG 2-(4-Hydroxyphenoxy)acetic Acid 1878-84-8 250mg $63 2026-06-03 Buy
TRC TRC-H801505-2.5G 2-(4-Hydroxyphenoxy)acetic Acid 1878-84-8 2.5g $120 2026-06-03 Buy
Product number Packaging Price Buy
439398 5g $54.8 Buy
H0992 5g $75 Buy
H0992 25g $243 Buy
TRC-H801505-250MG 250mg $63 Buy
TRC-H801505-2.5G 2.5g $120 Buy

4-HYDROXYPHENOXYACETIC ACID Chemical Properties,Uses,Production

Chemical Properties

off-white to beige fine crystalline powder

Uses

2-(4-Hydroxyphenoxy)acetic Acid is used in the design, synthesis and evaluation of postulated transient intermediate and substrate analogues as inhibitors of 4-hyroxyphenylpyruvate dioxygenase. Acts as a reagent in the preparation, anti-HIV and kinesin Eg5 inhibitory activities, QSAR, and modeling studies of triazolothiadiazole and triazolothiadiazine derivatives. Synthesis of thiadiazolotriazin-4-ones and study of their mosquito-larvicidal and antibacterial properties.

Definition

ChEBI: 4-Hydroxypheoxyacetate is a monocarboxylic acid.

General Description

(4-Hydroxyphenoxy)acetic acid along with formaldehyde ammonium salt forms a polyaromatic anionic compound RG-13577. RG-13577 mimics the synthetic heparin and specifically binds to the vascular smooth muscle cells (SMCs) and inhibits their proliferative growth. In the molecules of (4-hydroxyphenoxy)acetic acid, the carboxyl groups are held together by R22(8) hydrogen bonds.

4-HYDROXYPHENOXYACETIC ACID Preparation Products And Raw materials

4-HYDROXYPHENOXYACETIC ACID Suppliers

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4-HYDROXYPHENOXYACETIC ACID 2-(4-Hydroxyphenoxy)acetic acid 2-(4-Hydroxyphenoxy)ethanoic acid, 4-(Carboxymethoxy)phenol (P-HYDROXYPHENOXY)ACETIC ACID (4-hydroxyphenoxy)-aceticaci 4-Hydroxyphenoxyacetic acid, 98+% Acetic acid, 2-(4-hydroxyphenoxy)- 2-(4-hydroxyphenoxy)aceticaci 1878-84-8 HOC6H4OCH2CO2H Building Blocks Carbonyl Compounds Carboxylic Acids C8 Organic Building Blocks Phenoxyacetic Acids and Alcohols (substituted) Carbonyl Compounds Carboxylic Acids C8