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E3 ligase Ligand 14

E3 ligase Ligand 14 Structure
E3 ligase Ligand 14 structure
CAS No.
2241489-43-8
Chemical Name:
E3 ligase Ligand 14
Synonyms
CST 530, Phenol;E3 ligase Ligand 14;tert-butyl N-[(1S)-1-{[(1S)-1-cyclohexyl-2-[(2S,4S)-4-(3-hydroxyphenoxy)-2-{[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl}pyrrolidin-1-yl]-2-oxoethyl]carbamoyl}ethyl]-N-methylcarbamate;tert-Butyl ((S)-1-(((S)-1-Cyclohexyl-2-((2S,4S)-4-(3-hydroxyphenoxy)-2-(((R)-1,2,3,4-tetrahydronaphthalen-1-yl)carbamoyl)pyrrolidin-1-yl)-2-oxoethyl)amino)-1-oxopropan-2-yl)(methyl)carbamate
CBNumber:
CB18054707
Molecular Formula:
C38H52N4O7
Molecular Weight:
676.84
MDL Number:
MFCD32197260
MOL File:
Mol file
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:59:02
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E3 ligase Ligand 14 Properties

Boiling point 899.5±65.0 °C(Predicted)
Density 1.24±0.1 g/cm3(Predicted)
pka 9.55±0.10(Predicted)

E3 ligase Ligand 14 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth RPD48943 E3 Ligase ligand 14 2241489-43-8 5mg $1670.55 2026-06-05 Buy
Biosynth RPD48943 E3 Ligase ligand 14 2241489-43-8 10mg $2672.8 2026-06-05 Buy
Biosynth RPD48943 E3 Ligase ligand 14 2241489-43-8 25mg $5011.5 2026-06-05 Buy
Biosynth RPD48943 E3 Ligase ligand 14 2241489-43-8 50mg $8018.5 2026-06-05 Buy
ChemScene CS-0100097 E3 ligase Ligand 14 ≥98% 2241489-43-8 25mg $847 2026-06-04 Buy
Product number Packaging Price Buy
RPD48943 5mg $1670.55 Buy
RPD48943 10mg $2672.8 Buy
RPD48943 25mg $5011.5 Buy
RPD48943 50mg $8018.5 Buy
CS-0100097 25mg $847 Buy

E3 ligase Ligand 14 Chemical Properties, Uses, Production

Uses

E3 ligase Ligand 14 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 14 can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].

IC 50

IAP

References

[1] Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575. DOI:10.1021/acs.jmedchem.7b00168

E3 ligase Ligand 14 Preparation Products And Raw materials

Raw materials

Preparation Products

E3 ligase Ligand 14 Suppliers

Global Suppliers ( 8)
Supplier Tel Email Country ProdList Advantage
Daicel Chiral Technologies (China)CO.,LTD 021-50460086-9 15921403865 han_yajun@dctc.daicel.com China 7917 65
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1644 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 trendseenbio@gmail.com China 9067 58
Supplier Advantage
Daicel Chiral Technologies (China)CO.,LTD 65
Jilin Province Woda Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 58

View Latest Price from E3 ligase Ligand 14 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
E3 ligase Ligand 14 pictures 2026-01-05 E3 ligase Ligand 14
2241489-43-8
 $1980.00 10g TargetMol Chemicals Inc.

2241489-43-8 (E3 ligase Ligand 14) Related Search:

E3 ligase Ligand 18 E3 ligase Ligand 10 L-Prolinamide, 3-methyl-L-valyl-4-hydroxy-N-[(1S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-, (4R)- rac-((2R,3S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2-hydroxy-4-phenylbutanoyl)-D-leucine E3 ligase Ligand-Linker Conjugates 38
Carbamic acid, N-[(1S)-2-[[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(3-hydroxybenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]methylamino]-1-methyl-2-oxoethyl]-N-methyl-, 1,1-dimethylethyl ester E3 ligase Ligand 12

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E3 ligase Ligand 14 tert-Butyl ((S)-1-(((S)-1-Cyclohexyl-2-((2S,4S)-4-(3-hydroxyphenoxy)-2-(((R)-1,2,3,4-tetrahydronaphthalen-1-yl)carbamoyl)pyrrolidin-1-yl)-2-oxoethyl)amino)-1-oxopropan-2-yl)(methyl)carbamate tert-butyl N-[(1S)-1-{[(1S)-1-cyclohexyl-2-[(2S,4S)-4-(3-hydroxyphenoxy)-2-{[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl}pyrrolidin-1-yl]-2-oxoethyl]carbamoyl}ethyl]-N-methylcarbamate CST 530, Phenol 2241489-43-8