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E3 ligase Ligand 18

CAS No.
2241669-88-3
Chemical Name:
E3 ligase Ligand 18
Synonyms
E3 ligase Ligand 18;L-Cysteine, N-acetyl-S-[2-amino-9-[(4-chlorophenyl)methyl]-6,9-dihydro-6-oxo-1H-purin-8-yl]-;(R)-2-Acetamido-3-((2-amino-9-(4-chlorobenzyl)-6-oxo-6,9-dihydro-3H-purin-8-yl)thio)propanoic acid;(2R)-3-({2-amino-9-[(4-chlorophenyl)methyl]-6-oxo-6,9-dihydro-3H-purin-8-yl}sulfanyl)-2-acetamidopropanoic acid
CBNumber:
CB48054708
Molecular Formula:
C17H17ClN6O4S
Molecular Weight:
436.87
MDL Number:
MFCD32263215
MOL File:
2241669-88-3.mol
MSDS File:
SDS
Last updated:2026-05-28 02:40:22

E3 ligase Ligand 18 Properties

Density 1.68±0.1 g/cm3(Predicted)
pka 3.17±0.10(Predicted)
form Solid
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

E3 ligase Ligand 18 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0107241 E3 ligase Ligand 18 ≥98% 2241669-88-3 5mg $173 2026-06-04 Buy
ChemScene CS-0107241 E3 ligase Ligand 18 ≥98% 2241669-88-3 10mg $271 2026-06-04 Buy
ChemScene CS-0107241 E3 ligase Ligand 18 ≥98% 2241669-88-3 25mg $542 2026-06-04 Buy
ChemScene CS-0107241 E3 ligase Ligand 18 ≥98% 2241669-88-3 50mg $877 2026-06-04 Buy
ChemScene CS-0107241 E3 ligase Ligand 18 ≥98% 2241669-88-3 100mg $1408 2026-06-04 Buy
Product number Packaging Price Buy
CS-0107241 5mg $173 Buy
CS-0107241 10mg $271 Buy
CS-0107241 25mg $542 Buy
CS-0107241 50mg $877 Buy
CS-0107241 100mg $1408 Buy

E3 ligase Ligand 18 Chemical Properties, Uses, Production

Uses

E3 ligase Ligand 18 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 18 can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].

IC 50

Cereblon

References

[1] Heterocyclic compound. WO2018143403A1.

E3 ligase Ligand 18 Preparation Products And Raw materials

Raw materials

Preparation Products

E3 ligase Ligand 18 Suppliers

Global Suppliers ( 9)
Supplier Tel Email Country ProdList Advantage
Shanghai Chaolan Chemical Technology Center QQ:65489617 13301690235 Sales@ATKchemical.com China 9729 58
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1644 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Shanghai Haohong Pharmaceutical Co., Ltd. 400-8210725 4008210725 malulu@leyan.com China 54996 58
Suzhou Chenrui Biotechnology Co. LTD 17625585511 1580084073@qq.com China 992 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 trendseenbio@gmail.com China 9067 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Henan Mengtai Pharmaceutical Technology Co., Ltd 17634413542 1959525201@qq.com China 9011 58

E3 ligase Ligand 18 Spectrum

E3 ligase Ligand 18 L-Cysteine, N-acetyl-S-[2-amino-9-[(4-chlorophenyl)methyl]-6,9-dihydro-6-oxo-1H-purin-8-yl]- (2R)-3-({2-amino-9-[(4-chlorophenyl)methyl]-6-oxo-6,9-dihydro-3H-purin-8-yl}sulfanyl)-2-acetamidopropanoic acid (R)-2-Acetamido-3-((2-amino-9-(4-chlorobenzyl)-6-oxo-6,9-dihydro-3H-purin-8-yl)thio)propanoic acid 2241669-88-3