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H-Lys(Alloc)-OH

H-Lys(Alloc)-OH Structure
H-Lys(Alloc)-OH structure
CAS No.
6298-03-9
Chemical Name:
H-Lys(Alloc)-OH
Synonyms
NSC 45852;L-Lys(Aloc)-OH;nδ-alloc-l-lysine;H-LYS(ALLOC)-OH USP/EP/BP;Nε-Allyloxycarbonyl-L-lysine;Ne-Allyloxycarbonyl-L-lysine;H-Lys(Aloc)-OH (E-3065.0001);N6-[(2-Propen-1-yloxy)carbonyl]-L-lysine;L-Lysine, N6-[(2-propen-1-yloxy)carbonyl]-;(S)-6-(((Allyloxy)carbonyl)aMino)-2-aMinohexanoic acid
CBNumber:
CB1973060
Molecular Formula:
C10H18N2O4
Molecular Weight:
230.26
MDL Number:
MFCD00237142
MOL File:
6298-03-9.mol
MSDS File:
SDS
Last updated:2026-09-12 18:50:06
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H-Lys(Alloc)-OH Properties

Boiling point 414.9±45.0 °C(Predicted)
Density 1.153±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka 2.53±0.24(Predicted)
form solid
Appearance White to off-white Solid
optical activity [α]20/D +18.5±1°, c =1% in 1 M HCl
Major Application peptide synthesis
InChI 1S/C10H18N2O4/c1-2-7-16-10(15)12-6-4-3-5-8(11)9(13)14/h2,8H,1,3-7,11H2,(H,12,15)(H,13,14)/t8-/m0/s1
InChIKey JMZPOGGPUVRZMI-QMMMGPOBSA-N
SMILES N[C@@H](CCCCNC(=O)OCC=C)C(O)=O
UNSPSC Code 12352209
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H317
Precautionary statements  P280
PPE dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Risk Statements  43
Safety Statements  36/37
WGK Germany  WGK 3
Storage Class 11 - Combustible Solids
Hazard Classifications Skin Sens. 1

H-Lys(Alloc)-OH price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 74218 H-Lys(Alloc)-OH ≥99.0% 6298-03-9 1G $262 2026-04-30 Buy
Usbiological 285695 Ne-Allyloxycarbonyl-L-lysine Asreported 6298-03-9 500mg $340 2026-06-03 Buy
Usbiological 285695 Ne-Allyloxycarbonyl-L-lysine Asreported 6298-03-9 1g $549 2026-06-03 Buy
Usbiological 285695 Ne-Allyloxycarbonyl-L-lysine Asreported 6298-03-9 2g $758 2026-06-03 Buy
Usbiological 285695 Ne-Allyloxycarbonyl-L-lysine Asreported 6298-03-9 5g $1283 2026-06-03 Buy
Product number Packaging Price Buy
74218 1G $262 Buy
285695 500mg $340 Buy
285695 1g $549 Buy
285695 2g $758 Buy
285695 5g $1283 Buy

H-Lys(Alloc)-OH Chemical Properties, Uses, Production

Uses

peptide synthesis

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

L-Citrulline

372-75-8

Allyl chloroformate

2937-50-0

H-LYS(ALLOC)-OH

6298-03-9

Step 5. A mixed solution of L-citrulline (10 g, 68.4 mmol) and basic copper carbonate (15.12 g, 68.4 mmol) in distilled water (100 mL) was heated to reflux for 30 minutes. Solids generated during refluxing were removed by thermal filtration. The filtrate was cooled to 0 °C and the pH was adjusted to 9 by addition of anhydrous sodium carbonate (1.0 g). allyl chloroformate (10.8 mL, 102.6 mmol) was added slowly and dropwise while stirring at 0 °C. During dropwise addition, the pH of the reaction mixture was maintained at 9 by addition of anhydrous sodium carbonate (20 g). the reaction mixture was gradually warmed up to room temperature with continuous stirring for 12 h. The reaction was carried out by filtration. Upon completion of the reaction, the resulting blue solid product was quantitatively collected by filtration. The resulting copper salt solid of Orn (Alloc) was suspended in distilled water (200 mL) and thioacetamide (6.511 g, 86.66 mmol, 2 equiv) was added. The basic suspension was stirred at 50 °C for 3 h, during which time the solid gradually dissolved. Subsequently, the solution was acidified to pH 2 with 2 M hydrochloric acid and boiling was continued for 5 min. The resulting copper sulfide precipitate was removed by filtration. The filtrate was concentrated under reduced pressure to about 100 mL, at which point the hydrochloride product of Orn (Alloc) precipitated quantitatively as a white solid.

References

[1] Patent: WO2015/95227, 2015, A2. Location in patent: Page/Page column 168; 169

H-Lys(Alloc)-OH synthesis

372-75-8
2937-50-0
6298-03-9
Synthesis of H-Lys(Alloc)-OH from L-Citrulline and Allyl chloroformate

H-Lys(Alloc)-OH Preparation Products And Raw materials

Raw materials

Allyl chloroformate (Tert-Butoxy)Carbonyl Lys(Alloc)-OH L-Citrulline Sodium carbonate L-Lysine
Thioacetamide Cupric carbonate basic

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Preparation Products

H-Lys(Alloc)-OH Suppliers

Global Suppliers ( 65)
Supplier Tel Email Country ProdList Advantage
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632; sales@reading-chemicals.com China 15165 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66028182 17714375163 yftan@aikonchem.com China 16674 50
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
Chengdu Chuangkecheng Biological Technology Co., Ltd. 028-028-0000000 13008177686 sales@ckcbiotech.com China 899 55
Shanghai GL Peptide Ltd. +86-21-61263310 13764994101 fisherwang@glschina.com China 8059 55
Wuxi Asia Peptide Biotechnology Limited Company 0510-83583050 13771062561 willsun@peptide-search.com China 6713 58
Shanghai Haohong Pharmaceutical Co., Ltd. 400-8210725 400821072 malulu@leyan.com China 24933 58
Supplier Advantage
Energy Chemical 61
Shanghai Hanhong Scientific Co.,Ltd. 64
Bide Pharmatech Ltd. 60
Wuxi Zhongkun Biochemical Technology Co., Ltd. 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 50
Sigma-Aldrich 80
Chengdu Chuangkecheng Biological Technology Co., Ltd. 55
Shanghai GL Peptide Ltd. 55
Wuxi Asia Peptide Biotechnology Limited Company 58
Shanghai Haohong Pharmaceutical Co., Ltd. 58

View Latest Price from H-Lys(Alloc)-OH manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
H-LYS(ALLOC)-OH pictures 2019-07-06 H-LYS(ALLOC)-OH
6298-03-9
 $1.00 1KG 98% 1kg,5kg,100kg Career Henan Chemical Co

H-Lys(Alloc)-OH Spectrum

H-LYS(ALLOC)-OH(6298-03-9)1HNMR

6298-03-9 (H-Lys(Alloc)-OH) Related Search:

(S)-2-amino-3-(4-(2-tert-butoxy-2-oxoethyl)phenyl)propanoic acid 5-Hydroxytryptophan N-epsilon-Acetyl-L-lysine H-L-Tyr-NEt2.HCl H-L-Pen-OH.HCl.H2O
H-Lys(Boc)-OH Biocytin H-Lys(Boc)-OBzl·HCl H-L-Lys-NEt2.2HCl L-Phenylalanine, 4-cyclohexyl-
Fmoc-Lys(aloc)-OH 6-N-Alloc-L-lysine H-Lys(Alloc)-OH Z-Lys(aloc)-OH dcha DDE-L-Lys(Alloc)-OH dcha
Boc-Lys(aloc)-OH dcha Boc-Lys(Alloc)-OSu L-Ala-4PIP(Alloc)

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nδ-alloc-l-lysine (S)-6-(((Allyloxy)carbonyl)aMino)-2-aMinohexanoic acid NSC 45852 (2S)-2-Amino-6-[[(prop-2-en-1-yloxy)carbonyl]amino]hexanoic acid N6-[(2-Propen-1-yloxy)carbonyl]-L-lysine L-Lys(Aloc)-OH Ne-Allyloxycarbonyl-L-lysine (2S)-2-amino-6-(prop-2-enoxycarbonylamino)hexanoic acid L-Lysine, N6-[(2-propen-1-yloxy)carbonyl]- H-LYS(ALLOC)-OH USP/EP/BP Nε-Allyloxycarbonyl-L-lysine H-Lys(Aloc)-OH (E-3065.0001) 6298-03-9 SiChem