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ChemicalBook >> CAS DataBase List >>1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI)

1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI)

1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI) Structure
1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI) structure
CAS No.
199336-83-9
Chemical Name:
1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI)
Synonyms
tert-butyl (R)-3-(methylamino)pyrrolidine-1-carboxylate;1-N-Boc-3-(R)-(Methylamino) pyrrolidine;(R)-1-Boc-3-(methylamino)pyrrolidine HCl;(R)-1-Boc-3-(Methylamino)pyrrolidinehydrochloride;(S)-1-Boc-3-methylaminopyrrolidine, hydrochloride;2-Methyl-2-propanyl methyl(3-pyrrolidinyl)carbamate;(R)-benzyl 3-(methylamino)pyrrolidine-1-carboxylate;ert-butyl(3R)-3-(methylamino)pyrrolidine-1-carboxylate;tert-Butyl (3R)-3-(methylamino)pyrrolidine-1-carboxylate;1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethyleth...
CBNumber:
CB21281008
Molecular Formula:
C10H20N2O2
Molecular Weight:
200.28
MDL Number:
MFCD09752961
MOL File:
199336-83-9.mol
MSDS File:
SDS
Last updated:2026-05-27 23:55:13
Product description Number Pack Size Price
tert-Butyl (3R)-3-(methylamino)pyrrolidine-1-carboxylate >98% OR308134 250mg $21
tert-Butyl (3R)-3-(methylamino)pyrrolidine-1-carboxylate >98% OR308134 1g $25
tert-Butyl (3R)-3-(methylamino)pyrrolidine-1-carboxylate >98% OR308134 5g $94
tert-Butyl (3R)-3-(methylamino)pyrrolidine-1-carboxylate >98% OR308134 25g $374
tert-Butyl (3R)-3-(methylamino)pyrrolidine-1-carboxylate >98% OR308134 100g $1272
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1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI) Properties

Boiling point 269 ºC
Density 1.03
Flash point 117 ºC
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka 10.02±0.20(Predicted)
Appearance Colorless to light yellow Liquid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
RIDADR  UN2735
HS Code  2933998090

1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI) price More Price(53)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR308134 tert-Butyl (3R)-3-(methylamino)pyrrolidine-1-carboxylate >98% 199336-83-9 250mg $21 2026-06-04 Buy
Apolloscientific OR308134 tert-Butyl (3R)-3-(methylamino)pyrrolidine-1-carboxylate >98% 199336-83-9 1g $25 2026-06-04 Buy
Apolloscientific OR308134 tert-Butyl (3R)-3-(methylamino)pyrrolidine-1-carboxylate >98% 199336-83-9 5g $94 2026-06-04 Buy
Apolloscientific OR308134 tert-Butyl (3R)-3-(methylamino)pyrrolidine-1-carboxylate >98% 199336-83-9 25g $374 2026-06-04 Buy
Apolloscientific OR308134 tert-Butyl (3R)-3-(methylamino)pyrrolidine-1-carboxylate >98% 199336-83-9 100g $1272 2026-06-04 Buy
Product number Packaging Price Buy
OR308134 250mg $21 Buy
OR308134 1g $25 Buy
OR308134 5g $94 Buy
OR308134 25g $374 Buy
OR308134 100g $1272 Buy

1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI) Chemical Properties,Uses,Production

Application

(R)-3-(methylamino)pyrrolidine-1-carboxylic acid tert-butyl ester can be used as an organic synthesis intermediate and a pharmaceutical intermediate, mainly in laboratory research and development processes and chemical production processes.

Synthesis

1-N-Boc-(R)-(methylamino)-pyrrolidine Hydrochloride

1004538-35-5

1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI)

199336-83-9

Step 7-2: 1.18 g of (R)-1-(tert-butoxycarbonyl)-3-methylaminopyrrolidine hydrochloride (chemical purity: 99.9 area%) was mixed with 2.30 g of 23 wt. % brine, 4.71 g of toluene and 734 mg of 30 wt. % aqueous sodium hydroxide solution, and was prepared in accordance with the methodology described in Step 7-1. After stirring the reaction mixture, a partitioning operation was carried out. The organic layer was concentrated and dried under vacuum to give 946 mg of tert-butyl (R)-3-(methylamino)pyrrolidine-1-carboxylate as a colorless, transparent liquid (chemical purity: 99.3 area%, yield 97%).1H-NMR (CDCl3) data: δ (ppm) 1.45 (s, 9H), 1.71 (m, 2H), 2.04 (m, 1H). 2.44 (s, 3H), 3.03-3.28 (m, 2H), 3.29-3.65 (m, 3H).

References

[1] Patent: EP2050735, 2009, A1. Location in patent: Page/Page column 20

1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI) Preparation Products And Raw materials

Raw materials

1-N-Boc-(R)-(methylamino)-pyrrolidine Hydrochloride Sodium hydroxide Water Toluene

Preparation Products

1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI) Suppliers

Global( 117)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29640 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10403 58
Jinan Carbotang Biotech Co.,Ltd. 		+8615866703830 figo.gao@foxmail.com China 8497 58
Accela ChemBio Inc. 		+1-858-6993322 info@accelachem.com United States 21193 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49979 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29792 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051 joe@yuhengpharm.com CHINA 21142 58
Shanghai Rlavie Technology Co ltd 		+86-021-67759270 +8617717059219 sales@rlavie.com China 1030 58
Win-Win chemical CO., Limited 		+86-0086-577-64498589 +86-15355981851 sales@win-winchemical.com China 14304 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
Shenzhen Nexconn Pharmatechs Ltd 		58
Jinan Carbotang Biotech Co.,Ltd. 		58
Accela ChemBio Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		58
Shanghai Rlavie Technology Co ltd 		58
Win-Win chemical CO., Limited 		58

View Lastest Price from 1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI) pictures 2025-04-04 1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI)
199336-83-9
 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
tert-butyl (3R)-3-(methylamino)pyrrolidine-1-carboxylate pictures 2022-04-22 tert-butyl (3R)-3-(methylamino)pyrrolidine-1-carboxylate
199336-83-9
 98%min 100kgs/month Shanghai Rlavie Technology Co ltd
1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI) pictures 2020-01-08 1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI)
199336-83-9
 1KG 98%;99% 1kg； 5kg；10kg；25kg Career Henan Chemical Co

1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI) Spectrum

1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI)(199336-83-9)1HNMR

199336-83-9(1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI))Related Search:

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1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI) (R)-3-(Methylamino)pyrrolidine-1-carboxylic acid tert-butyl ester tert-Butyl (3R)-3-(methylamino)pyrrolidine-1-carboxylate (R)-1-Boc-3-(Methylamino)pyrrolidinehydrochloride (R)-1-Boc-3-(methylamino)pyrrolidine HCl (S)-1-Boc-3-methylaminopyrrolidine, hydrochloride 1-N-Boc-3-(R)-(Methylamino) pyrrolidine (R)-benzyl 3-(methylamino)pyrrolidine-1-carboxylate 2-Methyl-2-propanyl methyl(3-pyrrolidinyl)carbamate 1-Pyrrolidinecarboxylicacid,3-(MethylaMino)-,1,1-diMethylethylester,(3R)- tert-butyl (R)-3-(methylamino)pyrrolidine-1-carboxylate ert-butyl(3R)-3-(methylamino)pyrrolidine-1-carboxylate 1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI) USP/EP/BP 1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethyleth... 199336-83-9 AMINOACID