illudin M
- CAS No.
- 1146-04-9
- Chemical Name:
- illudin M
- Synonyms
- illudin M;(3S)-2,3-Dihydro-3α,6β-dihydroxy-2,2,4,6-tetramethylspiro[5H-indene-5,1'-cyclopropan]-7(6H)-one;(3'S,6'R)-2',3'-Dihydro-3',6'-dihydroxy-2',2',4',6'-tetramethylspiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one;(3'S,6'R)-3',6'-dihydroxy-2',2',4',6'-tetramethyl-2',3',6',7'-tetrahydrospiro[cyclopropane-1,5'-inden]-7'-one;Spiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one, 2',3'-dihydro-3',6'-dihydroxy-2',2',4',6'-tetramethyl-, (3'S,6'R)-
- CBNumber:
- CB21385676
- Molecular Formula:
- C15H20O3
- Molecular Weight:
- 248.32
- MDL Number:
- MFCD01683965
- MOL File:
- 1146-04-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Illudin M ≥85% | 22062 | 1mg | $369 |
| Illudin M ≥85% | 22062 | 5mg | $1286 |
| Illudin M | FI178320 | 5mg | $3223.3 |
| Illudin M 99.53% | CS-0085822 | 1mg | $542 |
| Illudin M 99.53% | CS-0085822 | 5mg | $1137 |
| Melting point | 120-122.5° (Matsumoto); mp 128-130° (McMorris) |
|---|---|
| Boiling point | 452.4±45.0 °C(Predicted) |
| Density | 1.24±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble |
| form | A solid |
| pka | 12.57±0.70(Predicted) |
| color | Off-white to light yellow |
| InChI | InChI=1S/C15H20O3/c1-8-10-9(7-13(2,3)12(10)17)11(16)14(4,18)15(8)5-6-15/h7,12,17-18H,5-6H2,1-4H3/t12-,14+/m1/s1 |
| InChIKey | QVMDIQLUNODCTG-OCCSQVGLSA-N |
| SMILES | C12([C@](O)(C)C(=O)C3C(=C1C)[C@@H](O)C(C)(C)C=3)CC2 |
| FDA UNII | 0ASO6A4L61 |
illudin M price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 22062 | Illudin M ≥85% | 1146-04-9 | 1mg | $369 | 2026-04-30 | Buy |
| Cayman Chemical | 22062 | Illudin M ≥85% | 1146-04-9 | 5mg | $1286 | 2026-04-30 | Buy |
| Biosynth | FI178320 | Illudin M | 1146-04-9 | 5mg | $3223.3 | 2026-06-04 | Buy |
| ChemScene | CS-0085822 | Illudin M 99.53% | 1146-04-9 | 1mg | $542 | 2026-06-04 | Buy |
| ChemScene | CS-0085822 | Illudin M 99.53% | 1146-04-9 | 5mg | $1137 | 2026-06-04 | Buy |
illudin M Chemical Properties,Uses,Production
Description
Illudin M is a cytotoxic sesquiterpene from the fungus O. illudens that alkylates DNA. It is cytotoxic to HL-60 human leukemia cells at 6-100 nM. Illudin M was used as a base structure for the development of potential anticancer agents with less toxicity and improved efficacy. It is closely related to illudin S , which has been the focus of additional studies.
Uses
Illudin M is a cytotoxic sesquiterpene from Omphalotus illudens and Granulobasidium vellereum. It acts as an alkylating agent that can cause inhibition of cell growth or replication.
Definition
ChEBI: Illudin M is a sesquiterpenoid.
References
[1] J. JACOBSON. Pharmacokinetics, Safety, and Antiviral Effects of Hypericin, a Derivative of St. John’s Wort Plant, in Patients with Chronic Hepatitis C Virus Infection[J]. Antimicrobial Agents and Chemotherapy, 2001, 45 1: 517-524. DOI: 10.1128/aac.45.2.517-524.2001
[2] M J KELNER. Preclinical evaluation of illudins as anticancer agents.[J]. Cancer research, 1987, 47 12: 3186-3189.
[3] R SCHOBERT. Anticancer active illudins: recent developments of a potent alkylating compound class.[J]. Current medicinal chemistry, 2011, 18 6: 790-807. DOI: 10.2174/092986711794927766
illudin M Preparation Products And Raw materials
Raw materials
Preparation Products
illudin M Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-17392712779 | 1097@dideu.com | China | 3989 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 | contact@trustwe.com | China | 5742 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Zhejiang Huida Biotech Co., LTD | 008613515763466 8615669048680 | wendy@huidabiotech.com | CHINA | 87 | 58 |
| Shanghai Minbiotech Co., Ltd. | +8617315815539 | sales@minbiotech.com | CHINA | 129 | 58 |
| AFINE CHEMICALS LIMITED | +86-571-85134551 +86-18958018566 | info@afinechem.com | China | 15058 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49709 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +86-18051384581 | sales@chemhifuture.com | China | 3123 | 58 |
| Wuhan Jingkang en Biomedical Technology Co., Ltd | +86-0086-13720134139 | orders@jknbiochem.com | China | 5215 | 58 |
