illudin S
- CAS No.
- 1149-99-1
- Chemical Name:
- illudin S
- Synonyms
- Illudin;Lampterol;CS-1385;Lunamycin;Illusin S;illudin S;llludin S;NSC-626369;NSC 400979;Illudine S
- CBNumber:
- CB91318110
- Molecular Formula:
- C15H20O4
- Molecular Weight:
- 264.32
- MDL Number:
- MFCD00870487
- MOL File:
- 1149-99-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Illudin S ≥98% | 17451 | 1mg | $334 |
| Illudin S ≥98% | 17451 | 5mg | $1329 |
| llludin S | FL178321 | 5mg | $3598.05 |
| Illudin S 99.80% | CS-0089316 | 1mg | $320 |
| Illudin S 99.80% | CS-0089316 | 5mg | $1083 |
| More product size | |||
| Melting point | 124-126℃ |
|---|---|
| Boiling point | 327.55°C (rough estimate) |
| Density | 1.0583 (rough estimate) |
| refractive index | 1.4300 (estimate) |
| storage temp. | -20°C, Inert atmosphere |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | A light yellow solid |
| pka | 12.50±0.70(Predicted) |
| color | Off-white to yellow |
| InChI | InChI=1S/C15H20O4/c1-8-10-9(6-13(2,7-16)12(10)18)11(17)14(3,19)15(8)4-5-15/h6,12,16,18-19H,4-5,7H2,1-3H3/t12-,13+,14+/m1/s1 |
| InChIKey | DDLLIYKVDWPHJI-RDBSUJKOSA-N |
| SMILES | C12([C@](O)(C)C(=O)C3C(=C1C)[C@@H](O)[C@@](CO)(C)C=3)CC2 |
| FDA UNII | EWJ0GY2H7X |
illudin S price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 17451 | Illudin S ≥98% | 1149-99-1 | 1mg | $334 | 2026-04-30 | Buy |
| Cayman Chemical | 17451 | Illudin S ≥98% | 1149-99-1 | 5mg | $1329 | 2026-04-30 | Buy |
| Biosynth | FL178321 | llludin S | 1149-99-1 | 5mg | $3598.05 | 2026-06-04 | Buy |
| ChemScene | CS-0089316 | Illudin S 99.80% | 1149-99-1 | 1mg | $320 | 2026-06-04 | Buy |
| ChemScene | CS-0089316 | Illudin S 99.80% | 1149-99-1 | 5mg | $1083 | 2026-06-04 | Buy |
illudin S Chemical Properties,Uses,Production
Description
Illudins are fungal sesquiterpenes that, through their unique DNA alkylating actions, have anticancer potential. Illudin S is a cytotoxic illudin that is converted, intracellularly, to metabolites that cause a complete block of cell cycling at the G1-S phase interface, particularly in myeloid and T-lymphocyte leukemia cells (IC50 = 6-11 nM). T-lymphocyte leukemia CEM cells that are resistant to doxorubicin , epipodophyllotoxins, and 1-β-D-arabinofuranosylcytosine display only 2-fold increased resistance to illudin S. Illudin S metabolites induce DNA damage that is not repaired by the processes that counter conventional DNA alkylating agents.
Uses
Illudin S is potent antitumor sesquiterpene, first isolated from the fungus, Clitocybe illudens, in 1963. Illudin S is metabolically activated to reactive intermediates that bind DNA. The DNA damage appears to differ from that of other reactive metabolites. Importantly, illudin S exhibits in vitro and in vivo potency against multi-drug resistant tumours.
Uses
Illudin S is a potent antitumor sesquiterpene.
Definition
ChEBI: Illudin S is a sesquiterpenoid.
References
[1] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras.
[2] NICOLAAS G.J JASPERS . Anti-tumour compounds illudin S and Irofulven induce DNA lesions ignored by global repair and exclusively processed by transcription- and replication-coupled repair pathways[J]. DNA Repair, 2002, 1 12: Pages 1027-1038. DOI: 10.1016/s1568-7864(02)00166-0
illudin S Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-17392712779 | 1097@dideu.com | China | 3989 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 | contact@trustwe.com | China | 5742 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Zhejiang Huida Biotech Co., LTD | 008613515763466 8615669048680 | wendy@huidabiotech.com | CHINA | 87 | 58 |
| Shanghai Minbiotech Co., Ltd. | +8617315815539 | sales@minbiotech.com | CHINA | 129 | 58 |
| AFINE CHEMICALS LIMITED | +86-571-85134551 +86-18958018566 | info@afinechem.com | China | 15058 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +86-18051384581 | sales@chemhifuture.com | China | 3123 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +86-15355479329 | market18@leapchem.com | China | 43303 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 50108 | 58 |
View Lastest Price from illudin S manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-31 | illudin S
1149-99-1
|
20kg | 99% | 20 tons | Qingdao RENAS Polymer Material Co., Ltd. | ||
 |
2026-05-11 | Illudin S
1149-99-1
|
$157.00-561.00 | 99.55% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-12-24 | illudin S
1149-99-1
|
1KG | 99.0% | 10 tons | Shaanxi Dideu Medichem Co. Ltd |
