ChemicalBook >> CAS DataBase List >>5-Amino-6-chloro-3-pyridinecarboxylic acid methyl ester

5-Amino-6-chloro-3-pyridinecarboxylic acid methyl ester

CAS No.
211915-96-7
Chemical Name:
5-Amino-6-chloro-3-pyridinecarboxylic acid methyl ester
Synonyms
Fampridine Impurity 231;5-AMino-6-chloro-nicotinic acid Methyl ester;Methyl 5-amino-6-chloro-3-pyridinecarboxylate;Methyl 5-aMino-6-chloropyridine-3-carboxylate;5-Amino-6-chloro-3-pyridinecarboxylic acid methyl ester;3-Pyridinecarboxylic acid, 5-aMino-6-chloro-, Methyl ester
CBNumber:
CB21501511
Molecular Formula:
C7H7ClN2O2
Molecular Weight:
186.6
MDL Number:
MFCD02180841
MOL File:
211915-96-7.mol
MSDS File:
SDS
Last updated:2026-05-28 00:04:15
Product description Number Pack Size Price
Methyl 5-amino-6-chloropyridine-3-carboxylate LIA91596 2.5g $324.5
Methyl 5-amino-6-chloropyridine-3-carboxylate 95% OR901819 100mg $21
Methyl 5-amino-6-chloropyridine-3-carboxylate 95% OR901819 250mg $36
Methyl 5-amino-6-chloropyridine-3-carboxylate 95% OR901819 1g $58
Methyl 5-amino-6-chloropyridine-3-carboxylate 95% OR901819 5g $277

5-Amino-6-chloro-3-pyridinecarboxylic acid methyl ester Properties

Boiling point 328.2±37.0 °C(Predicted)
Density 1.384±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka 0.20±0.10(Predicted)
Appearance Off-white to light yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2933399990

5-Amino-6-chloro-3-pyridinecarboxylic acid methyl ester price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth LIA91596 Methyl 5-amino-6-chloropyridine-3-carboxylate 211915-96-7 2.5g $324.5 2026-06-04 Buy
Apolloscientific OR901819 Methyl 5-amino-6-chloropyridine-3-carboxylate 95% 211915-96-7 100mg $21 2026-06-04 Buy
Apolloscientific OR901819 Methyl 5-amino-6-chloropyridine-3-carboxylate 95% 211915-96-7 250mg $36 2026-06-04 Buy
Apolloscientific OR901819 Methyl 5-amino-6-chloropyridine-3-carboxylate 95% 211915-96-7 1g $58 2026-06-04 Buy
Apolloscientific OR901819 Methyl 5-amino-6-chloropyridine-3-carboxylate 95% 211915-96-7 5g $277 2026-06-04 Buy
Product number Packaging Price Buy
LIA91596 2.5g $324.5 Buy
OR901819 100mg $21 Buy
OR901819 250mg $36 Buy
OR901819 1g $58 Buy
OR901819 5g $277 Buy

5-Amino-6-chloro-3-pyridinecarboxylic acid methyl ester Chemical Properties,Uses,Production

Synthesis

Methyl-6-chloro-5-nitronicotinate

59237-53-5

5-Amino-6-chloro-3-pyridinecarboxylic acid methyl ester

211915-96-7

General procedure for the synthesis of 5-amino-6-chloronicotinic acid methyl ester from 6-chloro-5-nitronicotinic acid: a suspension of methyl 6-chloro-5-nitronicotinic acid (1 eq.), iron powder (5.2 eq.) and NH4Cl (5.3 eq.) in methanol was heated and reacted for 2 hr at 75 °C. Upon completion of the reaction, the mixture was filtered through a diatomaceous earth pad while hot and the filtrate was subsequently concentrated in vacuum to afford the target product methyl 5-amino-6-chloronicotinate in 56% yield.

References

[1] Patent: WO2010/71853, 2010, A1. Location in patent: Page/Page column 68
[2] Patent: WO2013/169704, 2013, A2. Location in patent: Paragraph 0290
[3] Patent: WO2015/95795, 2015, A1. Location in patent: Paragraph 0378

5-Amino-6-chloro-3-pyridinecarboxylic acid methyl ester Preparation Products And Raw materials

5-Amino-6-chloro-3-pyridinecarboxylic acid methyl ester Suppliers

Global( 44)Suppliers
Supplier Tel Email Country ProdList Advantage
HANGZHOU LEAP CHEM CO., LTD.
+86-571-87711850 +86-15355479329 market18@leapchem.com China 43303 58
Aladdin Scientific
tp@aladdinsci.com United States 50108 58
Suzhou ARTK Medchem Co., Ltd.
+86-18168183658 sales1@artkmedchem.com China 39007 58
Shanghai Hong-chuang Pharma Tech Co., Ltd. 18151128828 hc-sales@foxmail.com China 2635 55
Changzhou Hopschain Chemical Co.,Ltd. 85528066 13775048983 sales@hopschem.com China 31548 55
Shanghai Anmike Chemical Co. Ltd. 微信 17321281695 18019252918 sale@amkchem.com China 9988 55
Hubei Yangxin Medical Technology Co., Ltd. 15374522761 3003392093@yongstandards.com China 9995 55
Aikon International Limited 025-58859352 13913916777 dt3@aikonchem.com China 15490 58
Shanghai Sealing Biotechnology Co. Ltd.. 15721176654;15710104046 1815535157@qq.com China 982 58
Changzhou Kechem Bio-Scientific Co., LTD. 0519-68985668 13685222090 sales@kechem.cn China 26012 58

5-Amino-6-chloro-3-pyridinecarboxylic acid methyl ester Spectrum

5-Amino-6-chloro-3-pyridinecarboxylic acid methyl ester 3-Pyridinecarboxylic acid, 5-aMino-6-chloro-, Methyl ester 5-AMino-6-chloro-nicotinic acid Methyl ester Methyl 5-aMino-6-chloropyridine-3-carboxylate Methyl 5-amino-6-chloro-3-pyridinecarboxylate Fampridine Impurity 231 211915-96-7 pharmacetical