3-Methyl-2-([1-[3-(trimethylammonio)propyl]-4(1H)-quinolinylidene]methyl)-1,3-benzothiazol-3-ium diiodide
![3-Methyl-2-([1-[3-(trimethylammonio)propyl]-4(1H)-quinolinylidene]methyl)-1,3-benzothiazol-3-ium diiodide Structure](CAS/GIF/157199-59-2.gif)
- CAS No.
- 157199-59-2
- Chemical Name:
- 3-Methyl-2-([1-[3-(trimethylammonio)propyl]-4(1H)-quinolinylidene]methyl)-1,3-benzothiazol-3-ium diiodide
- Synonyms
- TO-PRO 1;TWO-PRO? 1;To-pro 1 Iodide;NIR-Red Dead Cell-1 Dye;TO-PRO-1 Green Fluorescent Dye;TWO-PRO 1 (equivalent to TO-PRO 1) *5 mM DMSO Solution* *CAS 157199-59-2*;trimethyl-[3-[4-[(3-methyl-1,3-benzothiazol-2-ylidene)methyl]quinolin-1-ium-1-yl]propyl]azanium;trimethyl-[3-[4-[(Z)-(3-methyl-1,3-benzothiazol-2-ylidene)methyl]quinolin-1-ium-1-yl]propyl]azanium;QUINOLINIUM, 4-[(3-METHYL-2(3H)-BENZOTHIAZOLYLIDENE)METHYL]-1-[3-(TRIMETHYLAMMONIO)PROPYL]-, DIIODIDE;3-Methyl-2-([1-[3-(trimethylammonio)propyl]-4(1H)-quinolinylidene]methyl)-1,3-benzothiazol-3-ium diiodide
- CBNumber:
- CB2162131
- Molecular Formula:
- C24H29I2N3S
- Molecular Weight:
- 645.38
- MDL Number:
- MFCD06409927
- MOL File:
- 157199-59-2.mol
- MSDS File:
- SDS
3-Methyl-2-([1-[3-(trimethylammonio)propyl]-4(1H)-quinolinylidene]methyl)-1,3-benzothiazol-3-ium diiodide Properties
| Melting point | >250℃ |
|---|---|
| solubility | Soluble in dimethyl sulfoxide |
| form | powder |
| color | Red-brown |
| Appearance | Green solution |
| ex/em | 515/531 nm |
| ε(extinction coefficient) | 62800 cm−1M−1 |
| Φ(quantum yield) | 0.25 |
| λmax | 515 nm |
| Biological Applications | Nucleic acid hybridization; nucleic acid assay; nucleic acid fragment sizing; nucleic acid sequencing; detecting nucleic acids,cells,Human papilloma virus (HPV),microstructures; counting embryoblasts,leukocytes; monitoring |
3-Methyl-2-([1-[3-(trimethylammonio)propyl]-4(1H)-quinolinylidene]methyl)-1,3-benzothiazol-3-ium diiodide price
3-Methyl-2-([1-[3-(trimethylammonio)propyl]-4(1H)-quinolinylidene]methyl)-1,3-benzothiazol-3-ium diiodide Chemical Properties, Uses, Production
Description
TO-TAP-1 (Thiazole Orange Monomer, also known as TO-PRO®-1) is a green fluorescent carbocyanine monomeric dye. TO-TAP-1 is a cell-impermeant nucleic acid stain that is nonfluorescent in the absence of nucleic acids but exhibits a multiple fluorescence enhancement upon binding to dsDNA.
The bright fluorescence signal and low background make TO-TAP-1 ideal for staining nucleic acids on microarrays, as well as for nuclear and chromosome counterstaining in multicolor fluorescence labeling experiments. TO-TAP-1 is non-cytotoxic and may be used for long-term monitoring of cell viability and dead cell detection in culture.
Chemical Properties
Appearance: Green solution
ex/em: 515/531 nm
Extinction coefficient (ε): 62800 cm1M1
Quantum yield (Φ): 0.25
Uses
TO-PRO 1 is a DNA binding fluorochrome, that atached to the surface of the Feraheme (FH) nanoparticle (NP), to obtain a fluorochrome-functionalized NP. TO-PRO 1 binds DNA through intercalation, and acts as a vital fluorochrome for necrotic cells[1].
Definition
ChEBI: A C1 cyanine dye having benzothiazolium-2-yl and quinolinium-4-yl substituents.
References
[1] Hoonsung Cho, et al. Fluorochrome-functionalized nanoparticles for imaging DNA in biological systems. ACS Nano. 2013 Mar 26;7(3):2032-41. DOI:10.1021/nn305962n
Abs/Em Maxima
513/533 nm
3-Methyl-2-([1-[3-(trimethylammonio)propyl]-4(1H)-quinolinylidene]methyl)-1,3-benzothiazol-3-ium diiodide Preparation Products And Raw materials
Raw materials
Preparation Products
3-Methyl-2-([1-[3-(trimethylammonio)propyl]-4(1H)-quinolinylidene]methyl)-1,3-benzothiazol-3-ium diiodide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
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| Xi'an Biolite Biotech, Inc. | 029-029-68064558 18502920169 | xiaodong@tjbiolite.com | China | 2949 | 58 |
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| Xi'an Reinforce Biotechnology Co., Ltd. | 15339237155 15339237155 | 2229108118@qq.com | China | 721 | 58 |
