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H-D-Pro-Phe-Arg-chloromethylketone

H-D-Pro-Phe-Arg-chloromethylketone structure

CAS No.: 88546-74-1

Chemical Name:: H-D-Pro-Phe-Arg-chloromethylketone

Synonyms: pFR-CMK;DPRO-PHE-ARG-CMK;H-D-Pro-Phe-Arg-CMK;DPRO-PHE-ARG-CHLOROMETHYLKETONE;H-D-Pro-Phe-Arg-chloromethylketone;H-D-Pro-Phe-Arg-chloromethylketone trifluoroacetate salt;L-Phenylalaninamide, D-prolyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-(2-chloroacetyl)butyl]-

CBNumber:: CB2171627

Molecular Formula:: C21H31ClN6O3

Molecular Weight:: 450.96

MDL Number:: MFCD00237853

MOL File:: 88546-74-1.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:50:24

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H-D-Pro-Phe-Arg-chloromethylketone Properties

Density	1.37±0.1 g/cm3(Predicted)
storage temp.	-15°C
pka	13.01±0.46(Predicted)
form	Solid
color	White to off-white
Sequence	{d-Pro}-Phe-{Arg-Chloromethylketone}

H-D-Pro-Phe-Arg-chloromethylketone price More Price(21)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biosynth	FP111023	H-D-Pro-Phe-Arg-chloromethylketone trifluoroacetate salt	88546-74-1	5mg	$900	2026-06-04	Buy
Biosynth	FP111023	H-D-Pro-Phe-Arg-chloromethylketone trifluoroacetate salt	88546-74-1	2mg	$900	2026-06-04	Buy
Biosynth	FP111023	H-D-Pro-Phe-Arg-chloromethylketone trifluoroacetate salt	88546-74-1	1mg	$900	2026-06-04	Buy
Biosynth	FP111023	H-D-Pro-Phe-Arg-chloromethylketone trifluoroacetate salt	88546-74-1	10mg	$957.1	2026-06-04	Buy
Biosynth	FP111023	H-D-Pro-Phe-Arg-chloromethylketone trifluoroacetate salt	88546-74-1	25mg	$2081	2026-06-04	Buy

Product number	Packaging	Price	Buy
FP111023	5mg	$900	Buy
FP111023	2mg	$900	Buy
FP111023	1mg	$900	Buy
FP111023	10mg	$957.1	Buy
FP111023	25mg	$2081	Buy

H-D-Pro-Phe-Arg-chloromethylketone Chemical Properties, Uses, Production

Uses

D-Pro-Phe-Arg-Chloromethylketone, a inhibitor of coagulation factor XII and plasma kallikrein, plays an important role in thrombosis and inflammation[1].

References

[1] Katrin F Nickel, et al. Factor XII as a Therapeutic Target in Thromboembolic and Inflammatory Diseases. Arterioscler Thromb Vasc Biol. 2017 Jan;37(1):13-20. DOI:10.1161/ATVBAHA.116.308595

H-D-Pro-Phe-Arg-chloromethylketone Preparation Products And Raw materials

Raw materials

Preparation Products

H-D-Pro-Phe-Arg-chloromethylketone Suppliers

Global Suppliers ( 34)

Supplier	Tel	Email	Country	ProdList	Advantage
GL Biochem (Shanghai) Ltd	21-61263452 13641803416	ymbetter@glbiochem.com	China	9981	64
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15350	60
Creative Peptides		info@creative-peptides.com	United States	6083	56
Shanghai Chaolan Chemical Technology Center	QQ：65489617 13301690235	Sales@ATKchemical.com	China	9729	58
Nanjing Peptide Biotech Ltd.	025-58361106-805 15951641583	zhao.xu@njpeptide.com	China	9976	55
Hangzhou Peptidego Biotech Co.,Ltd.	0571-87213919 15967184799	Eric@peptidego.com	China	7872	58
BOC Sciences	16314854226; +8616314854226	inquiry@bocsci.com	United States	19852	58
Nanchang Tianzhen Biotechnology Co., Ltd	13758194781 13173652190	522013271@qq.com	China	2436	58
Nanjing TGpeptide Biotechnology Co.,Ltd.	18115476705	sales@tgpeptide.com	China	3058	58

Supplier	Advantage
GL Biochem (Shanghai) Ltd	64
Shanghai Hanhong Scientific Co.,Ltd.	64
Chemsky (shanghai) International Co.,Ltd	60
Creative Peptides	56
Shanghai Chaolan Chemical Technology Center	58
Nanjing Peptide Biotech Ltd.	55
Hangzhou Peptidego Biotech Co.,Ltd.	58
BOC Sciences	58
Nanchang Tianzhen Biotechnology Co., Ltd	58
Nanjing TGpeptide Biotechnology Co.,Ltd.	58

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DPRO-PHE-ARG-CHLOROMETHYLKETONE DPRO-PHE-ARG-CMK H-D-Pro-Phe-Arg-chloromethylketone trifluoroacetate salt H-D-Pro-Phe-Arg-CMK L-Phenylalaninamide, D-prolyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-(2-chloroacetyl)butyl]- pFR-CMK H-D-Pro-Phe-Arg-chloromethylketone 88546-74-1