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2-Amino-N-methylbenzenesulfonamide

2-Amino-N-methylbenzenesulfonamide Structure
2-Amino-N-methylbenzenesulfonamide structure
CAS No.
16288-77-0
Chemical Name:
2-Amino-N-methylbenzenesulfonamide
Synonyms
N-Methyl-2-aminobenzenesulfonamide;2-Amino-N-methylbenzenesulfonamide;BenzenesulfonaMide, 2-aMino-N-Methyl-;2-aMino-N-Methylbenzene-1-sulfonaMide;2-amino-N-methylbenzenesulfonamide(SALTDATA: HCl)
CBNumber:
CB2191047
Molecular Formula:
C7H10N2O2S
Molecular Weight:
186.23
MDL Number:
MFCD04035388
MOL File:
16288-77-0.mol
MSDS File:
SDS
Last updated:2026-09-12 18:50:25
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2-Amino-N-methylbenzenesulfonamide Properties

Melting point 59-60℃
Boiling point 352.9±44.0 °C(Predicted)
Density 1.308
storage temp. 2-8°C(protect from light)
pka 11+-.0.10(Predicted)
Appearance Light yellow to brown Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338

2-Amino-N-methylbenzenesulfonamide price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS94589 2-Amino-N-methylbenzenesulfonamide 97% 16288-77-0 1g $59 2026-06-04 Buy
Activate Scientific AS94589 2-Amino-N-methylbenzenesulfonamide 97% 16288-77-0 5g $138 2026-06-04 Buy
Matrix Scientific 072356 2-Amino-N-methylbenzenesulfonamide 16288-77-0 1.00g $370 2026-05-18 Buy
Matrix Scientific 072356 2-Amino-N-methylbenzenesulfonamide 16288-77-0 5.00g $998 2026-05-18 Buy
Synthonix A66568 2-Amino-N-methylbenzenesulfonamide >98% 16288-77-0 1g $45 2026-05-06 Buy
Product number Packaging Price Buy
AS94589 1g $59 Buy
AS94589 5g $138 Buy
072356 1.00g $370 Buy
072356 5.00g $998 Buy
A66568 1g $45 Buy

2-Amino-N-methylbenzenesulfonamide Chemical Properties, Uses, Production

Description

2-Amino-N-methylbenzenesulfonamide is obtained by treating 2-nitrobenzenesulfonyl chloride with methylamine and subsequent reduction. Used as a dye component. The amides of 2-aminobenzenesulfonic acid can be treated with aldehydes or orthoformic acid esters to give 1,2,4-benzothiadiazine 1,1-dioxides or their dihydro compounds; these substances have been proposed as diuretics.

Synthesis

N-Methyl-2-nitrobenzenesulphonamide

23530-40-7

2-AMINO-N-METHYLBENZENESULFONAMIDE

16288-77-0

Step B / Intermediate C4: Synthesis of 2-amino-N-methylbenzenesulfonamide To a solution of N-methyl-2-nitrobenzenesulfonamide (26 g, 0.12 mol) in methanol (500 mL) was added 10% palladium carbon catalyst (2 g). The reaction mixture was stirred at room temperature under hydrogen atmosphere for 3 hours. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated under reduced pressure to afford the target product 2-amino-N-methylbenzenesulfonamide (22 g, 98% yield). The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3): δ 7.45-7.48 (dd, 1H, J=1.6 Hz, 8.0 Hz), 7.24-7.31 (m, 2H), 6.81-6.83 (dd, 1H, J=0.6 Hz, 8.0 Hz), 6.60-6.65 (m, 1H), 5.89 (s 2H), 2.370-2.374 (d, 3H, J=1.6Hz).

References

[1] Patent: WO2012/92880, 2012, A1. Location in patent: Page/Page column 64
[2] Angewandte Chemie - International Edition, 2010, vol. 49, # 29, p. 4955 - 4957
[3] Patent: WO2007/45868, 2007, A1. Location in patent: Page/Page column 47
[4] Farmaco, Edizione Scientifica, 1954, vol. 9, p. 661,678, 680
[5] Farmaco, Edizione Scientifica, 1957, vol. 12, p. 495,499, 500

2-Amino-N-methylbenzenesulfonamide Preparation Products And Raw materials

Raw materials

N-Methyl-2-nitrobenzenesulphonamide Hydrogen Methanol

Preparation Products

BenzenesulfonaMide, 2-[(2,5-dichloro-4-pyriMidinyl)aMino]-N-Methyl-

2-Amino-N-methylbenzenesulfonamide Suppliers

Global Suppliers ( 64)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Atop-Pharma (Shanghai) Technology Co., Ltd. +86 (21) 5196-9732 China 996 57
Chengdu Forest Science and Technology Development Co., Ltd. 18030648795 18030648795 sales@cdforestchem.com China 1998 58
Nanjing Norris-Pharm Technology Co., Ltd 13901585132 sales@norris-pharm.com China 8869 55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 13913916777 cfzhang@aikonchem.com China 19902 55
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7545 61
Shanghai Keepontech Co.,Ltd 021-54849683 13601642561 sales@keepontech.com China 998 59
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 18201 56
Shanghai Witofly Chemical Co.,Ltd sales@witofly.com China 2853 52
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Adamas Reagent, Ltd. 59
Atop-Pharma (Shanghai) Technology Co., Ltd. 57
Chengdu Forest Science and Technology Development Co., Ltd. 58
Nanjing Norris-Pharm Technology Co., Ltd 55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 55
Haoyuan Chemexpress Co., Ltd. 61
Shanghai Keepontech Co.,Ltd 59
9ding chemical ( Shanghai) Limited 56
Shanghai Witofly Chemical Co.,Ltd 52

View Latest Price from 2-Amino-N-methylbenzenesulfonamide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-AMINO-N-METHYLBENZENESULFONAMIDE pictures 2020-01-13 2-AMINO-N-METHYLBENZENESULFONAMIDE
16288-77-0
 $1.00 1g 99.0% 100kg Career Henan Chemical Co

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2-amino-N-methylbenzenesulfonamide(SALTDATA: HCl) N-Methyl-2-aminobenzenesulfonamide 2-aMino-N-Methylbenzene-1-sulfonaMide BenzenesulfonaMide, 2-aMino-N-Methyl- 2-Amino-N-methylbenzenesulfonamide 16288-77-0