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2'-Chloro-4',5'-difluoroacetophenone

2'-Chloro-4',5'-difluoroacetophenone structure

CAS No.: 121872-94-4

Chemical Name:: 2'-Chloro-4',5'-difluoroacetophenone

Synonyms: 2-Chloro-4,5-difluroacetophenone;2-CHLORO-4,5-DIFLUOROACETOPHENONE;2-CHLORO-4,5-DIFLUOROPHENYLACETONE;2'-Chloro-4',5'-difluoroacetophenone;2''-Chloro-4'',5''-difluoroacetophenone;2-CHLORO-4,5-DIFLUOROPHENYLACETOPHENONE;2'-Chloro-4',5'-difluoroacetophenone97%;1-(2-chloro-4,5-difluorophenyl)ethanone;2'-Chloro-4',5'-difluoroacetophenone,95%;Ethanone, 1-(2-chloro-4,5-difluorophenyl)-

CBNumber:: CB2215419

Molecular Formula:: C8H5ClF2O

Molecular Weight:: 190.57

MDL Number:: MFCD00671761

MOL File:: 121872-94-4.mol

MSDS File:: SDS

Last updated:2026-05-27 23:59:55

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2'-Chloro-4',5'-difluoroacetophenone Properties

Boiling point	211.4±35.0 °C(Predicted)
Density	1.348±0.06 g/cm3(Predicted)
storage temp.	Storage temp. 2-8°C
Appearance	Colorless to light yellow Liquid
CAS DataBase Reference	121872-94-4(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319

Precautionary statements

P280g-P305+P351+P338

Hazard Codes

HazardClass

IRRITANT

HS Code

2914790090

NFPA 704

	1
2		0

2'-Chloro-4',5'-difluoroacetophenone price More Price(31)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Apolloscientific	PC8096	2'-Chloro-4',5'-difluoroacetophenone >98%	121872-94-4	1g	$21	2026-06-04	Buy
Apolloscientific	PC8096	2'-Chloro-4',5'-difluoroacetophenone >98%	121872-94-4	5g	$24	2026-06-04	Buy
Apolloscientific	PC8096	2'-Chloro-4',5'-difluoroacetophenone >98%	121872-94-4	25g	$54	2026-06-04	Buy
Apolloscientific	PC8096	2'-Chloro-4',5'-difluoroacetophenone >98%	121872-94-4	100g	$207	2026-06-04	Buy
Apolloscientific	PC8096	2'-Chloro-4',5'-difluoroacetophenone >98%	121872-94-4	500g	$925	2026-06-04	Buy

Product number	Packaging	Price	Buy
PC8096	1g	$21	Buy
PC8096	5g	$24	Buy
PC8096	25g	$54	Buy
PC8096	100g	$207	Buy
PC8096	500g	$925	Buy

2'-Chloro-4',5'-difluoroacetophenone Chemical Properties, Uses, Production

Synthesis

Preparation of 2'-chloro-4',5'-difluoroacetophenone

At a temperature of 20°C to 40°C, 23.6 g (0.3 mol) acetyl chloride was added to a mixture containing 29.7 g (0.2 mol) 1-chloro-3,4-difluorobenzene and 40.0 g (0.3 mol) aluminum chloride, and the mixture was then stirred at 120°C for 2 hours. While still very hot, the mixture was poured onto 250 g of ice, and the separated oil was extracted with chloroethane.

The extract was neutralized and washed with water, and the solvent was distilled off under reduced pressure to obtain 31.2 g (yield: 82%) of 2'-chloro-4',5'-difluoroacetophenone, boiling point: 65℃-67℃/4-5 mmHg.

Uses

2'-Chloro-4',5'-difluoroacetophenone is used as an intermediate in the production of various drugs.

2'-Chloro-4',5'-difluoroacetophenone Preparation Products And Raw materials

Raw materials

Preparation Products

2-Chloro-4,5-difluorobenzoic acid

2'-Chloro-4',5'-difluoroacetophenone Suppliers

Global Suppliers ( 94)

Supplier	Tel	Email	Country	ProdList	Advantage
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
Wuhan Chemwish Technology Co., Ltd	86-027-67849912	sales@chemwish.com	China	35884	56
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18		China	18187	66
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.	+86-21-54098501	sales@sinch.com.cn	China	11592	64
Adamas Reagent, Ltd.	400-6009262 15618770481	yhx@titansci.com	China	14098	59
Tianjin Jinyuda Chemical Co., Ltd.	022-58013646 13011382049	sales@jinyudachem.com	China	1976	55
Hangzhou Sage Chemical Co., Ltd.	+86057186818502 13588463833	info@sagechem.com	China	10265	58
Shanghai Aladdin Bio-Chem Technology Co.,LTD	400-6206333 13167063860	anhua.mao@aladdin-e.com	China	29985	65
Clearsynth Labs Limited	+91-22-26355700	info@clearsynth.com	India	9656	58
Bide Pharmatech Ltd.	400-164-7117 18317119277	product02@bidepharm.com	China	40000	60

Supplier	Advantage
Alfa Aesar	84
Wuhan Chemwish Technology Co., Ltd	56
Capot Chemical Co., Ltd	66
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.	64
Adamas Reagent, Ltd.	59
Tianjin Jinyuda Chemical Co., Ltd.	55
Hangzhou Sage Chemical Co., Ltd.	58
Shanghai Aladdin Bio-Chem Technology Co.,LTD	65
Clearsynth Labs Limited	58
Bide Pharmatech Ltd.	60

View Latest Price from 2'-Chloro-4',5'-difluoroacetophenone manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-12-25	2'-Chloro-4',5'-difluoroacetophenone 121872-94-4	$1.00	1g	99%	1000KGS	Career Henan Chemical Co

2'-Chloro-4',5'-difluoroacetophenone
121872-94-4
$1.00
99%
Career Henan Chemical Co

2'-Chloro-4',5'-difluoroacetophenone Spectrum

2'-Chloro-4',5'-difluoroacetophenone(121872-94-4)¹HNMR

121872-94-4 (2'-Chloro-4',5'-difluoroacetophenone) Related Search:

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2-CHLORO-4,5-DIFLUOROACETOPHENONE 2-CHLORO-4,5-DIFLUOROPHENYLACETOPHENONE 2-CHLORO-4,5-DIFLUOROPHENYLACETONE 2'-chloro-4',5'-difluoroacetophenonedup 21889 2-Chloro-4,5-difluroacetophenone 1-(2-chloro-4,5-difluorophenyl)ethanone 2'-Chloro-4',5'-difluoroacetophenone97% Ethanone, 1-(2-chloro-4,5-difluorophenyl)- 2'-Chloro-4',5'-difluoroacetophenone,95% 2'-Chloro-4',5'-difluoroacetophenone 2''-Chloro-4'',5''-difluoroacetophenone 2′-Chloro-4′,5′-difluoroacetophenone, CAS 121872-94-4 121872-94-4 C8H5CI2O Aromatic Acetophenones & Derivatives (substituted)