ChemicalBook >> CAS DataBase List >>9alpha,15S-dihydroxy-11-oxo-prosta-5z,12e-dien-1-oic acid

9alpha,15S-dihydroxy-11-oxo-prosta-5z,12e-dien-1-oic acid

CAS No.
64072-89-5
Chemical Name:
9alpha,15S-dihydroxy-11-oxo-prosta-5z,12e-dien-1-oic acid
Synonyms
Δ12-PGD2;Brn 6071542;delta(sup12)-pgd2;Δ12-Prostaglandin D2;DELTA12-PROSTAGLANDIN D2;delta(sup12)-prostaglandind2;9alpha,15S-dihydroxy-11-oxo-prosta-5z,12e-dien-1-oic acid;(5Z,12E,15S)-9α,15-Dihydroxy-11-oxoprosta-5,12-dien-1-oic acid;9,15-dihydroxy-11-oxo-,(5z,9-alpha,12e,15s)-prosta-12-dien-1-oicacid;(5z,9-alpha,12e,15s)-9,15-dihydroxy-11-oxoprosta-5,12-dien-1-oicacid
CBNumber:
CB2223948
Molecular Formula:
C20H32O5
Molecular Weight:
352.47
MDL Number:
MFCD01694758
MOL File:
64072-89-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:50:27

9alpha,15S-dihydroxy-11-oxo-prosta-5z,12e-dien-1-oic acid Properties

solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 2 mg/ml
EWG's Food Scores 1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)Health Hazard (GHS08)
GHS02,GHS07,GHS08
Signal word  Danger
NFPA 704
3
2 0

9alpha,15S-dihydroxy-11-oxo-prosta-5z,12e-dien-1-oic acid price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 12650 Δ12-Prostaglandin D2 ≥98% 64072-89-5 500μg $57 2026-04-30 Buy
Cayman Chemical 12650 Δ12-Prostaglandin D2 ≥98% 64072-89-5 1mg $102 2026-04-30 Buy
Cayman Chemical 12650 Δ12-Prostaglandin D2 ≥98% 64072-89-5 5mg $478 2026-04-30 Buy
Cayman Chemical 12650 Δ12-Prostaglandin D2 ≥98% 64072-89-5 10mg $842 2026-04-30 Buy
aablocks AA00EBHI Δ12-Prostaglandin D2 ≥98% 64072-89-5 1mg $102 2026-05-28 Buy
Product number Packaging Price Buy
12650 500μg $57 Buy
12650 1mg $102 Buy
12650 5mg $478 Buy
12650 10mg $842 Buy
AA00EBHI 1mg $102 Buy

9alpha,15S-dihydroxy-11-oxo-prosta-5z,12e-dien-1-oic acid Chemical Properties, Uses, Production

Description

Prostaglandin D2 (PGD2) is one of the five primary enzymatic prostaglandins derived directly from PGH2. PGD2 is produced abundantly in the CSF by the lipocalin-type PGD synthase, and in the periphery by myeloid cells including mast cells and basophils by a second, hematopoietic-type PGD synthase. PGD2 is chemically unstable, and its use and analysis is complicated by its short in vivo half-life. Δ12-PGD2 is one of the initial chemical decomposition products of PGD2. Δ12-PGD2 is an intermediate in the pathway leading to Δ12-PGJ2, which is a cyclopentenone prostaglandin with antimitotic and carcinogenic activities. The metabolism of Δ12-PGD2 involves addition of thiol nucleophiles, as is the case with the majority of cyclopentenone prostaglandins.

Uses

Δ12(E)-Prostaglandin D2 is a derivative of Prostaglandin D2 (HY-101988). Prostaglandin D2 is one of the major Prostaglandins actively produced in the brain of various mammals[1].

References

[1] J Atsmon, et al. Formation of thiol conjugates of 9-deoxy-delta 9,delta 12(E)-prostaglandin D2 and delta 12(E)-prostaglandin D2. Biochemistry. 1990 Apr 17;29(15):3760-5. DOI:10.1021/bi00467a023

9alpha,15S-dihydroxy-11-oxo-prosta-5z,12e-dien-1-oic acid Preparation Products And Raw materials

Raw materials

Preparation Products

9alpha,15S-dihydroxy-11-oxo-prosta-5z,12e-dien-1-oic acid Suppliers

Global Suppliers ( 11)
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
DELTA12-PROSTAGLANDIN D2 (5z,9-alpha,12e,15s)-9,15-dihydroxy-11-oxoprosta-5,12-dien-1-oicacid 9,15-dihydroxy-11-oxo-,(5z,9-alpha,12e,15s)-prosta-12-dien-1-oicacid delta(sup12)-pgd2 delta(sup12)-prostaglandind2 (5Z,12E,15S)-9α,15-Dihydroxy-11-oxoprosta-5,12-dien-1-oic acid Δ12-PGD2 Δ12-Prostaglandin D2 Brn 6071542 Prosta-5,12-dien-1-oic acid, 9,15-dihydroxy-11-oxo-, (5Z,9-alpha,12E,15S)- Prosta-5,12-dien-1-oic acid, 9,15-dihydroxy-11-oxo-, (5Z,9α,12E,15S)- 9alpha,15S-dihydroxy-11-oxo-prosta-5z,12e-dien-1-oic acid 64072-89-5