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5-BROMO-1H-INDAZOLE-3-CARBOXYLIC ACID

5-BROMO-1H-INDAZOLE-3-CARBOXYLIC ACID structure

CAS No.: 1077-94-7

Chemical Name:: 5-BROMO-1H-INDAZOLE-3-CARBOXYLIC ACID

Synonyms: 5-BroMo-1H-indazole-3-car...;5-Bromo-3-carboxy-1H-indazole;5-BROMOINDAZOLE-3-CARBOXYLIC ACID;5-BROMO-3-INDAZOLECARBOXYLIC ACID;5-broMo-1H-indazol-3-carboxylic acid;5-BROMO-1H-INDAZOLE-3-CARBOXYLIC ACID;5-bromobenzopyrazole-3-carboxylic acid;1H-INDAZOLE-3-CARBOXYLIC ACID, 5-BROMO-

CBNumber:: CB7719134

Molecular Formula:: C8H5BrN2O2

Molecular Weight:: 241.04

MDL Number:: MFCD05663979

MOL File:: 1077-94-7.mol

Last updated:2025-09-12 22:14:43

Product description	Number	Pack Size	Price
5-Bromo-1H-indazole-3-carboxylicacid	B683773	100mg	$45
5-Bromo-1H-indazole-3-carboxylicacid	B683773	500mg	$65
5-Bromo-1H-indazole-3-carboxylicacid	B683773	250mg	$55
5-Bromo-1H-indazole-3-carboxylic acid 98%	4H21-9-01	250mg	$56
5-Bromo-1H-indazole-3-carboxylic acid	FB56350	1g	$150
More product size

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5-BROMO-1H-INDAZOLE-3-CARBOXYLIC ACID Properties

Melting point	289-292°C
Boiling point	493.4±25.0 °C(Predicted)
Density	1.946±0.06 g/cm3(Predicted)
storage temp.	2-8°C
form	solid
pka	2.81±0.30(Predicted)
color	Off-white
InChI	InChI=1S/C8H5BrN2O2/c9-4-1-2-6-5(3-4)7(8(12)13)11-10-6/h1-3H,(H,10,11)(H,12,13)
InChIKey	AMJVXOOGGBPVCZ-UHFFFAOYSA-N
SMILES	N1C2=C(C=C(Br)C=C2)C(C(O)=O)=N1
CAS DataBase Reference	1077-94-7(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H335-H319-H302+H312+H332

Precautionary statements

P271-P261-P280

Hazard Codes

Xi,Xn

Risk Statements

Safety Statements

22-26-36/37/39

Hazard Note

Irritant

HS Code

2933998090

NFPA 704

	1
2		0

5-BROMO-1H-INDAZOLE-3-CARBOXYLIC ACID price More Price(39)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	B683773	5-Bromo-1H-indazole-3-carboxylicacid	1077-94-7	100mg	$45	2021-12-16	Buy
TRC	B683773	5-Bromo-1H-indazole-3-carboxylicacid	1077-94-7	500mg	$65	2021-12-16	Buy
TRC	B683773	5-Bromo-1H-indazole-3-carboxylicacid	1077-94-7	250mg	$55	2021-12-16	Buy
SynQuest Laboratories	4H21-9-01	5-Bromo-1H-indazole-3-carboxylic acid 98%	1077-94-7	250mg	$56	2021-12-16	Buy
Biosynth Carbosynth	FB56350	5-Bromo-1H-indazole-3-carboxylic acid	1077-94-7	1g	$150	2021-12-16	Buy

Product number	Packaging	Price	Buy
B683773	100mg	$45	Buy
B683773	500mg	$65	Buy
B683773	250mg	$55	Buy
4H21-9-01	250mg	$56	Buy
FB56350	1g	$150	Buy

5-BROMO-1H-INDAZOLE-3-CARBOXYLIC ACID Chemical Properties,Uses,Production

Uses

5-Bromo-1H-indazole-3-carboxylic acid an important chemical product. It is mainly used as a raw material in chemical synthesis for the preparation of other compounds. Its derivative 5-Bromo-1H-indazole-3-carboxylic acid ethyl ester can be used as a protein kinase inhibitor, which can be used for the treatment and prevention of diseases.

Synthesis

4498-67-3

1077-94-7

Step 1: Indazole-3-carboxylic acid (CXXXI) (1.0 g, 6.16 mmol) was suspended in glacial acetic acid (60 mL) and heated to 120 °C until a clear solution was formed. The solution was then cooled to 90 °C. A solution of bromine (0.633 mL, 12.33 mmol) in glacial acetic acid (2 mL) was slowly added dropwise to the solution at 90 °C. After addition, the reaction continued to be heated at 90 °C for 16 hours. After completion of the reaction, the solution was cooled to room temperature and poured into ice water and stirred at room temperature for 15 minutes. The precipitated solid was filtered, washed with cold water and dried under vacuum at room temperature to afford 5-bromo-1H-indazole-3-carboxylic acid (CXXXII) as a white solid (1.30 g, 5.39 mmol, 87.5% yield). The product was characterized by 1H NMR (DMSO-d6): δ 13.95 (s, 1H), 13.18 (br s, 1H), 8.21 (d, J = 1.2 Hz, 1H), 7.65 (d, J = 7.0 Hz, 1H), 7.56 (dd, J = 7.0, 1.2 Hz, 1H); ESIMS m/z 242.0 ([M + H]+. (calculated value C8H4BrN2O2).

References

[1] Patent: US2015/266825, 2015, A1. Location in patent: Paragraph 1359; 1360
[2] Patent: WO2018/75858, 2018, A1. Location in patent: Paragraph 0371; 0372
[3] Patent: CN107573327, 2018, A. Location in patent: Paragraph 0067; 0068; 0069; 0070
[4] Patent: US2005/90529, 2005, A1. Location in patent: Page/Page column 84-85
[5] Chemische Berichte, 1922, vol. 55, p. 1141,1157

5-BROMO-1H-INDAZOLE-3-CARBOXYLIC ACID synthesis

Synthesis of 5-BROMO-1H-INDAZOLE-3-CARBOXYLIC ACID from Indazole-3-carboxylic acid

5-BROMO-1H-INDAZOLE-3-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

5-Bromoisatin Indazole-3-carboxylic acid

Preparation Products

5-BROMO-1H-INDAZOLE-3-CARBALDEHYDE METHYL 5-BROMO-1H-INDAZOLE-3-CARBOXYLATE

5-BROMO-1H-INDAZOLE-3-CARBOXYLIC ACID Suppliers

Global( 211)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Suzhou Actchem Co., Ltd.	+8618762124502	actchem@qq.com	China	27	58
Zhengzhou Anbu Chem Co.,Ltd	+86-0371-88006763; +8615988602810	sales@anbuchem.com	China	3009	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-81148696 +86-17392712697	1022@dideu.com	China	3995	58
Anhui Ruihan Technology Co., Ltd	+8617756083858	daisy@anhuiruihan.com	China	973	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29830	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10000	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58

Supplier	Advantage
Suzhou Actchem Co., Ltd.	58
Zhengzhou Anbu Chem Co.,Ltd	58
Shaanxi Dideu Medichem Co. Ltd	58
Anhui Ruihan Technology Co., Ltd	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Fuxin Pharmaceutical	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58

View Lastest Price from 5-BROMO-1H-INDAZOLE-3-CARBOXYLIC ACID manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-12-24	5-BROMO-1H-INDAZOLE-3-CARBOXYLIC ACID 1077-94-7	US $0.10 / KG	1KG	98.0%	10	Shaanxi Dideu Medichem Co. Ltd
2025-09-13	5-BROMO-1H-INDAZOLE-3-CARBOXYLIC ACID 1077-94-7	US $0.00 / KG	0.10000000149011612KG	98%	1000KGS	Zhengzhou Anbu Chem Co.,Ltd
2025-04-04	5-BROMO-1H-INDAZOLE-3-CARBOXYLIC ACID 1077-94-7	US $0.00-0.00 / kg	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.

5-BROMO-1H-INDAZOLE-3-CARBOXYLIC ACID
1077-94-7
US $0.10 / KG
98.0%
Shaanxi Dideu Medichem Co. Ltd

5-BROMO-1H-INDAZOLE-3-CARBOXYLIC ACID
1077-94-7
US $0.00 / KG
98%
Zhengzhou Anbu Chem Co.,Ltd

5-BROMO-1H-INDAZOLE-3-CARBOXYLIC ACID
1077-94-7
US $0.00-0.00 / kg
98%
Henan Aochuang Chemical Co.,Ltd.

5-BROMO-1H-INDAZOLE-3-CARBOXYLIC ACID Spectrum

5-BROMO-1H-INDAZOLE-3-CARBOXYLIC ACID(1077-94-7)¹HNMR

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