ChemicalBook >> CAS DataBase List >>8,9-Dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride
8,9-Dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride
![8,9-Dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride Structure](CAS/GIF/75704-24-4.gif)
- CAS No.
- 75704-24-4
- Chemical Name:
- 8,9-Dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride
- Synonyms
- WAY 161503;WAY 161503 hydrochlo;WAY 161503 HYDROCHLORIDE;(Rac) WAY 161503,(Rac)WAY161503;1H-Pyrazino[1,2-a]quinoxalin-5(6H)-one, 8,9-dichloro-2,3,4,4a-tetrahydro-;8,9-Dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride
- CBNumber:
- CB2265207
- Molecular Formula:
- C11H11Cl2N3O
- Molecular Weight:
- 272.13
- MDL Number:
- MFCD06411596
- MOL File:
- 75704-24-4.mol
- MSDS File:
- SDS
Last updated:2026-09-12 18:50:36
| Boiling point | 513.9±50.0 °C(Predicted) |
|---|---|
| Density | 1.54±0.1 g/cm3(Predicted) |
| storage temp. | Desiccate at RT |
| solubility | DMF: 30 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 25 mg/ml; Ethanol: 1 mg/ml |
| form | A crystalline solid |
| pka | 12.09±0.20(Predicted) |
| color | Off-white to light yellow |
| FDA UNII | SCG2HM6F3D |
8,9-Dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride price More Price(26)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 17269 | WAY-161503 ≥98% | 75704-24-4 | 1mg | $36 | 2026-04-30 | Buy |
| Cayman Chemical | 17269 | WAY-161503 ≥98% | 75704-24-4 | 5mg | $103 | 2026-04-30 | Buy |
| Cayman Chemical | 17269 | WAY-161503 ≥98% | 75704-24-4 | 10mg | $169 | 2026-04-30 | Buy |
| Cayman Chemical | 17269 | WAY-161503 ≥98% | 75704-24-4 | 50mg | $667 | 2026-04-30 | Buy |
| ChemScene | CS-0109487 | (Rac)-WAY-161503 98.49% | 75704-24-4 | 5mg | $152 | 2026-06-04 | Buy |
8,9-Dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride Chemical Properties, Uses, Production
Uses
8,9-Dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one is a selective 5-hydroxytryptamine 2C receptor agonist with putative antidepressant like properties. It also blocks and decreases baseline nicotine-induced locomotor activity in rats.
Biological Activity
Potent and selective 5-HT 2C receptor agonist (K i = 4 nM; EC 50 = 12 nM). Antidepressant following systemic administration in vivo .
in vivo
(Rac)-WAY-161503 (3-30 mg/kg; intraperitoneal injection; male C57BL/6J mice) dose-dependently decreases locomotor activity, an effect that is blocked by the 5-HT2C/2B antagonist SER-082[1].
| Animal Model: | Male C57BL/6J mice with hallucinogen 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI)[1] |
| Dosage: | 3 mg/kg, 10 mg/kg, 30 mg/kg |
| Administration: | Intraperitoneal injection (i.p.) |
| Result: | Dose-dependently decreased locomotor activity, an effect that was blocked by the 5-HT2C/2B antagonist SER-082. |
IC 50
5-HT2C Receptor: 4 nM (Ki); 5-HT2C Receptor: 12 nM (EC50)
8,9-Dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
8,9-Dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride Suppliers
Global Suppliers ( 39)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8435 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Shanghai hongqu biomedical technology co. LTD | 88888888888 | hongquchem@qq.com | China | 5123 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44871 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 |
View Latest Price from 8,9-Dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-27 | (Rac)-WAY-161503
75704-24-4
|
$86.00-192.00 | 99.51% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-07-27 | (Rac)-WAY-161503
75704-24-4
|
$86.00-192.00 | 99.51% | 10g | TargetMol Chemicals Inc. |
-
- (Rac)-WAY-161503
75704-24-4
- $86.00-192.00
- 99.51%
- TargetMol Chemicals Inc.
-
- (Rac)-WAY-161503
75704-24-4
- $86.00-192.00
- 99.51%
- TargetMol Chemicals Inc.
75704-24-4 (8,9-Dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride) Related Search:
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8,9-Dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride
75704-24-4
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