ChemicalBook >> CAS DataBase List >>5-Benzyl-3,6-dioxo-2-piperazineacetic acid
5-Benzyl-3,6-dioxo-2-piperazineacetic acid
- CAS No.
- 5262-10-2
- Chemical Name:
- 5-Benzyl-3,6-dioxo-2-piperazineacetic acid
- Synonyms
- CYCLO(-ASP-PHE);AspartaMe Related CoMpound A;(2S,5S)-5-Benzyl-3,6-dioxo-2-piperazineacetic Acid;Cyclo(Phe-Asp-);CYCLO(L-ASP-L-PHE);Aspartame impurity A CRS;cyclo(aspartyl-phenylalanyl);Cyclo(-Asp-Phe) (G-1695.0250);Cyclo(-Asp-Phe) (G-1695.1000);Aspartame USP Related Compound A
- CBNumber:
- CB2271464
- Molecular Formula:
- C13H14N2O4
- Molecular Weight:
- 262.26
- MDL Number:
- MFCD00190764
- MOL File:
- 5262-10-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-09-12 18:50:36
| Melting point | 270-272 °C(lit.) |
|---|---|
| Boiling point | 667.4±40.0 °C(Predicted) |
| Density | 1.298±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Acetic Acid (Slightly, Heated, Sonicated), DMSO (Slightly) |
| form | powder |
| pka | 4.02±0.10(Predicted) |
| color | White to Off-White |
| optical activity | [α]20/D 9.0°, c = 0.9 in acetic acid |
| Major Application |
cleaning products cosmetics food and beverages personal care |
| InChI | InChI=1S/C13H14N2O4/c16-11(17)7-10-13(19)14-9(12(18)15-10)6-8-4-2-1-3-5-8/h1-5,9-10H,6-7H2,(H,14,19)(H,15,18)(H,16,17)/t9-,10-/m0/s1 |
| InChIKey | VNHJXYUDIBQDDX-UWVGGRQHSA-N |
| SMILES | N1C(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@@H]1CC(O)=O |
| FDA UNII | ZM82VP15YJ |
| UNSPSC Code | 85151701 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P305+P351+P338 |
| target organs | Respiratory system |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| HS Code | 2933599550 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
5-Benzyl-3,6-dioxo-2-piperazineacetic acid price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHR2420 | Aspartame Related Compound A Pharmaceutical Secondary Standard; Certified Reference Material | 5262-10-2 | 50MG | $563 | 2026-04-30 | Buy |
| Sigma-Aldrich | A1321000 | Aspartame impurity A European Pharmacopoeia (EP) Reference Standard | 5262-10-2 | 20 mg | $175 | 2026-04-30 | Buy |
| Sigma-Aldrich | 421650 | (2S-cis)-(?)-5-Benzyl-3,6-dioxo-2-piperazineacetic acid 97% | 5262-10-2 | 1g | $998 | 2026-04-30 | Buy |
| Sigma-Aldrich | 1043728 | Aspartame Related Compound A United States Pharmacopeia (USP) Reference Standard | 5262-10-2 | 25mg | $1380 | 2024-03-01 | Buy |
| TRC | TRC-B276305-50MG | (2S,5S)-5-Benzyl-3,6-dioxo-2-piperazineacetic Acid >95%(HPLC) | 5262-10-2 | 50mg | $131 | 2026-06-03 | Buy |
5-Benzyl-3,6-dioxo-2-piperazineacetic acid Chemical Properties, Uses, Production
Chemical Properties
White Solid
Uses
(2S,5S)-5-Benzyl-3,6-dioxo-2-piperazineacetic Acid (Aspartame EP Impurity A) is the diketopiperazine impurity of the sweetening agent Aspartame (A790015). It is also found in in processed cocoa powder.
General Description
(2S-cis)-(-)-5-Benzyl-3,6-dioxo-2-piperazineacetic acid is a piperazine scaffold that can be used to construct biologically active compounds with therapeutic applications.
5-Benzyl-3,6-dioxo-2-piperazineacetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
Global Suppliers ( 140)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 15967184799 | Eric@peptidego.com | China | 7872 | 58 |
| Foshan Heshuo Pharm technology Co., ltd | 15363639686 | heshuoyiyao@hotmail.com | China | 2488 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400 638 7771 | sales@heowns.com | China | 14412 | 57 |
| Sinopharm Chemical Reagent Co,Ltd. | 86-21-63210123 | sj_scrc@sinopharm.com | China | 9791 | 79 |
View Latest Price from 5-Benzyl-3,6-dioxo-2-piperazineacetic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-07-02 | (2S-cis)-(-)-5-Benzyl-3,6-dioxo-2-piperazineacetic acid 97%
5262-10-2
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- (2S-cis)-(-)-5-Benzyl-3,6-dioxo-2-piperazineacetic acid 97%
5262-10-2
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
5262-10-2 (5-Benzyl-3,6-dioxo-2-piperazineacetic acid) Related Search:
5-Benzyl-3,6-dioxo-2-piperazineacetic acid
2-Benzylpiperazine
cis-2,5-Dimethylpiperazine
DL-2-Aminopropionic anhydride
Cyclo(-Ala-Ala)
(S)-3-(2-Hydroxyethyl)-2,5-diketopiperazine
H-Phe-beta-Ala-OH
H-Asp-Phe-OH
Cyclo(-Ala-Gly)
Cyclo(-Asp-Gly)
1of4
Aspartame Impurity 1（Aspartame EP Impurity A）
2-[(2S,5S)-3,6-dioxo-5-(phenylmethyl)piperazin-2-yl]acetic acid
2-[(2S,5S)-3,6-dioxo-5-(phenylmethyl)piperazin-2-yl]ethanoic acid
2-[(2S,5S)-5-(benzyl)-3,6-diketo-piperazin-2-yl]acetic acid
(2S,5S)-5-Benzyl-3,6-dioxo-2-piperazineacetic Acid
Aspartame Related Compound A (25 mg) (5-Benzyl-3,6-dioxo-2-piperazineacetic Acid)
(2S,5S)-3,6-Dioxo-5-(phenylMethyl)-2-piperazineacetic Acid
(2S-cis)-3,6-Dioxo-5-(phenylMethyl)-2-piperazineacetic Acid
AspartaMe-Related CoMpound A, (2S,5S)-5-Benzyl-3,6-dioxo2-piperazineacetic acid
2-((2S,5S)-5-benzyl-3,6-dioxopiperazin-2-yl)acetic acid
(2S-cis)-(-)-5-Benzyl-3,6-dioxo-2-piperazineacetic acid 97%
2-(5-Benzyl-3,6-dioxopiperazin-2-yl)
(2S-CIS)-(-)-5-BENZYL-3,6-DIOXO-2-PIPERAZINEACETIC ACID
CYCLO(L-ASP-L-PHE)
(2S-cis)-(-)-5-benzyl-3,6-dioxo-2-piperazineaceti
cyclo(aspartyl-phenylalanyl)
(2S)-3,6-Dioxo-5β-(phenylmethyl)-2β-piperazineacetic acid
(2S)-3,6-Dioxo-5β-benzylpiperazine-2β-acetic acid
5β-Benzyl-3,6-dioxopiperazine-2β-acetic acid
Cyclo(Phe-Asp-)
Cefadroxil Impurity 3（Aspartame Degradation Product，Aspartame Impurity A）
Aspartame impurity A CRS
Aspartame USP Related Compound A
2-Piperazineacetic acid, 3,6-dioxo-5-(phenylmethyl)-, (2S,5S)-
Aspartame EP Impurity A/ Aspartame Related Compound A
Cyclo(-Asp-Phe) (G-1695.0250)
Cyclo(-Asp-Phe) (G-1695.1000)
Aspartame EP Impurity AQ: What is
Aspartame EP Impurity A Q: What is the CAS Number of
Aspartame EP Impurity A Q: What is the storage condition of
Aspartame EP Impurity A Q: What are the applications of
Aspartame EP Impurity A
Aspartame Related Compound A (5-Benzyl-3,6-dioxo-2-piperazineacetic Acid) (1043728)
(2S-cis)-(?)-5-Benzyl-3,6-dioxo-2-piperazineacetic acid
(2S,5S)-5-BENZYL-3,6-DIOXO-2-PIPERAZINEACETIC ACID，Cyclo（Asp-Phe）
5-Benzylo-3,6-dioxo-2-piperazineacetate
AspartaMe Related CoMpound A
CYCLO(-ASP-PHE)
5-Benzyl-3,6-dioxo-2-piperazineacetic acid
5262-10-2
5262-10-2 CAT号:B31006
526-10-2
Heterocyclic Building Blocks
Piperazines
Chiral Building Blocks
Asymmetric Synthesis
Aromatics
Heterocycles
Impurities
Intermediates & Fine Chemicals
Pharmaceuticals
Chiral Building Blocks
Heterocyclic Building Blocks
Piperazines
