Fmoc-Abu-OH
- CAS No.
- 135112-27-5
- Chemical Name:
- Fmoc-Abu-OH
- Synonyms
- FMoc-ABu;FMOC-L-AIB-OH;FMOC-L-ABU-OH;(S)-2-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)butanoic acid;FMOC-L-2-AMINOBUTYRIC ACID;Fmoc-2-Abu;Fomc-Abu-OH;Fmoc-Abu-OH;FMOC-2-ABU-OH;FMOC-ABU(2)-OH
- CBNumber:
- CB2290317
- Molecular Formula:
- C19H19NO4
- Molecular Weight:
- 325.36
- MDL Number:
- MFCD00080268
- MOL File:
- 135112-27-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 161-163°C |
|---|---|
| Boiling point | 550.7±33.0 °C(Predicted) |
| Density | 1+-.0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | 3.89±0.10(Predicted) |
| form | solid |
| color | White |
| optical activity | [α]20/D 22.0±2°, c = 1% in DMF |
| BRN | 7657232 |
| Major Application | peptide synthesis |
| InChI | 1S/C19H19NO4/c1-2-17(18(21)22)20-19(23)24-11-16-14-9-5-3-7-12(14)13-8-4-6-10-15(13)16/h3-10,16-17H,2,11H2,1H3,(H,20,23)(H,21,22)/t17-/m0/s1 |
| InChIKey | XQIRYUNKLVPVRR-KRWDZBQOSA-N |
| SMILES | CC[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O |
| UNSPSC Code | 12352209 |
| NACRES | NA.26 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P280-P302+P352-P362+P364 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 2924 29 70 | |||||||||
| HazardClass | IRRITANT | |||||||||
| Storage Class | 13 - Non Combustible Solids | |||||||||
| NFPA 704 |
|
Fmoc-Abu-OH price More Price(71)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.52048 | Fmoc-Abu-OH Novabiochem? | 135112-27-5 | 1g | $61.4 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.52048 | Fmoc-Abu-OH Novabiochem? | 135112-27-5 | 5G | $224 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.52048 | Fmoc-Abu-OH Novabiochem? | 135112-27-5 | 25g | $886 | 2026-04-30 | Buy |
| Sigma-Aldrich | 47511 | Fmoc-Abu-OH ≥98.0% (HPLC) | 135112-27-5 | 10g | $778 | 2023-06-20 | Buy |
| TCI Chemical | F1247 | (S)-2-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]butanoic Acid | 135112-27-5 | 5G | $66 | 2026-04-30 | Buy |
Fmoc-Abu-OH Chemical Properties, Uses, Production
Chemical Properties
White powder
Uses
L-Fmoc-Aminobutyric Acid,
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
Synthesis
1492-24-6
82911-69-1
135112-27-5
General procedure for the synthesis of Fmoc-L-2-aminobutyric acid from L-2-aminobutyric acid and 9-fluorenylmethyl-N-succinimidyl carbonate: L-2-aminobutyric acid (50.0 g) and sodium bicarbonate (NaHCO3, 81.5 g) were dissolved in water (750 mL) at 20-25 °C. Fmoc-OSu solution [prepared from 171.7 g of 9-fluorenylmethyl-N-succinimidyl carbonate dissolved in 1050 mL of tetrahydrofuran (THF)] was slowly added to the reaction mixture and the reaction was stirred at the same temperature for 5 hours. After completion of the reaction, the reaction mixture was acidified with dilute hydrochloric acid (HCl) to pH < 1.0. The resulting solid was collected by filtration and dried. The crude product was recrystallized from toluene and dried to give Fmoc-L-2-aminobutyric acid. Yield: 135 g; HPLC purity: 99.7%.
References
[1] Patent: WO2018/198131, 2018, A1. Location in patent: Page/Page column 11
Fmoc-Abu-OH Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
View Latest Price from Fmoc-Abu-OH manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-17 | FMOC-ABU-OH
135112-27-5
|
1kg | 98% | 1T | Sichuan HongRi Pharma-Tech Co.,Ltd | ||
 |
2026-08-13 | FMOC-ABU-OH
135112-27-5
|
1KG | 98% | 2000 | Shenzhen Nexcon Pharmatechs Ltd. | ||
 |
2019-07-06 | FMOC-ABU-OH
135112-27-5
|
$1.00 | 1KG | 99% | 20kg | Career Henan Chemical Co |
-
- FMOC-ABU-OH
135112-27-5
- 98%
- Sichuan HongRi Pharma-Tech Co.,Ltd
-
- FMOC-ABU-OH
135112-27-5
- 98%
- Shenzhen Nexcon Pharmatechs Ltd.
-
- FMOC-ABU-OH
135112-27-5
- $1.00
- 99%
- Career Henan Chemical Co
