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FMOC-ABU-OH

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Products Intro: Product Name:Fmoc-Abu-OH
CAS:135112-27-5
Purity:98% Package:1kg;|10kg;|100kg
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CAS:135112-27-5
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Products Intro: Product Name:L-2-(fmoc-amino)butyric acid
CAS:135112-27-5
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CAS:135112-27-5
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Products Intro: Product Name: FMOC-ABU-OH
CAS:135112-27-5
Purity:99% Package:1KG;1USD

FMOC-ABU-OH manufacturers

  • FMOC-ABU-OH
  • FMOC-ABU-OH pictures
  • $0.00/ kg
  • 2026-04-02
  • CAS:135112-27-5
  • Min. Order: 1kg
  • Purity: 98%
  • Supply Ability: 1T
  • FMOC-ABU-OH
  • FMOC-ABU-OH pictures
  • $0.00 / 1KG
  • 2026-03-30
  • CAS:135112-27-5
  • Min. Order: 1KG
  • Purity: 98%
  • Supply Ability: 2000
  • FMOC-ABU-OH
  • 	FMOC-ABU-OH pictures
  • $1.00 / 1KG
  • 2019-07-06
  • CAS:135112-27-5
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 20kg
FMOC-ABU-OH Basic information
Product Name:FMOC-ABU-OH
Synonyms:RARECHEM EM WB 0018;N-ALPHA-FMOC-L-ALPHA-AMINOBUTYRIC ACID;N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-ALPHA-AMINOBUTYRIC ACID;N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-2-AMINO-BUTANOIC ACID;N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-2-AMINOBUTYRIC ACID;FMOC-2-AMINOBUTANOIC ACID;FMOC-2-ABU-OH;FMOC-ABU(2)-OH
CAS:135112-27-5
MF:C19H19NO4
MW:325.36
EINECS:828-203-7
Product Categories:Unusual Amino Acids;Amino Acids
Mol File:135112-27-5.mol
FMOC-ABU-OH Structure
FMOC-ABU-OH Chemical Properties
Melting point 161-163°C
Boiling point 550.7±33.0 °C(Predicted)
density 1+-.0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka3.89±0.10(Predicted)
form solid
color White
Optical Rotation[α]20/D 22.0±2°, c = 1% in DMF
BRN 7657232
Major Applicationpeptide synthesis
InChI1S/C19H19NO4/c1-2-17(18(21)22)20-19(23)24-11-16-14-9-5-3-7-12(14)13-8-4-6-10-15(13)16/h3-10,16-17H,2,11H2,1H3,(H,20,23)(H,21,22)/t17-/m0/s1
InChIKeyXQIRYUNKLVPVRR-KRWDZBQOSA-N
SMILESCC[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O
Safety Information
Safety Statements 22-24/25
WGK Germany 3
HS Code 2924 29 70
HazardClass IRRITANT
Storage Class13 - Non Combustible Solids
MSDS Information
ProviderLanguage
SigmaAldrich English
FMOC-ABU-OH Usage And Synthesis
Chemical PropertiesWhite powder
UsesL-Fmoc-Aminobutyric Acid,
reaction suitabilityreaction type: Fmoc solid-phase peptide synthesis
Synthesis
L(+)-2-Aminobutyric acid

1492-24-6

N-(9-Fluorenylmethoxycarbonyloxy)succinimide

82911-69-1

FMOC-ABU-OH

135112-27-5

General procedure for the synthesis of Fmoc-L-2-aminobutyric acid from L-2-aminobutyric acid and 9-fluorenylmethyl-N-succinimidyl carbonate: L-2-aminobutyric acid (50.0 g) and sodium bicarbonate (NaHCO3, 81.5 g) were dissolved in water (750 mL) at 20-25 °C. Fmoc-OSu solution [prepared from 171.7 g of 9-fluorenylmethyl-N-succinimidyl carbonate dissolved in 1050 mL of tetrahydrofuran (THF)] was slowly added to the reaction mixture and the reaction was stirred at the same temperature for 5 hours. After completion of the reaction, the reaction mixture was acidified with dilute hydrochloric acid (HCl) to pH < 1.0. The resulting solid was collected by filtration and dried. The crude product was recrystallized from toluene and dried to give Fmoc-L-2-aminobutyric acid. Yield: 135 g; HPLC purity: 99.7%.

References[1] Patent: WO2018/198131, 2018, A1. Location in patent: Page/Page column 11
FMOC-ABU-OH Preparation Products And Raw materials
Raw materialsL(+)-2-Aminobutyric acid-->Fmoc-OSu-->Sodium bicarbonate-->Water-->Tetrahydrofuran
Tag:FMOC-ABU-OH(135112-27-5) Related Product Information
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