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ChemicalBook >> CAS DataBase List >>N,N,N',N'-Tetramethyl-1,4-phenylenediamine

N,N,N',N'-Tetramethyl-1,4-phenylenediamine

N,N,N',N'-Tetramethyl-1,4-phenylenediamine Structure
N,N,N',N'-Tetramethyl-1,4-phenylenediamine structure
CAS No.
100-22-1
Chemical Name:
N,N,N',N'-Tetramethyl-1,4-phenylenediamine
Synonyms
N,N,N',N'-Tetramethyl-p-phenylenediamine;TMPPD;Wurster's blue;Tetramethyl-p-phenylenediamine;N,N,N',N'-Tetramethyl-1,4-Benzenediamine;N,N,N′,N′-Tetramethyl-p-phenylenediamine;N1,N1,N4,N4-Tetramethylbenzene-1,4-diamine;tl85;TL 85;WursterBlue]
CBNumber:
CB2300445
Molecular Formula:
C10H16N2
Molecular Weight:
164.25
MDL Number:
MFCD00008309
MOL File:
100-22-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 00:06:38
Product description Number Pack Size Price
N,N,N′,N′-Tetramethyl-p-phenylenediamine 99%, powder T7394 5g $123
N,N,N′,N′-Tetramethyl-p-phenylenediamine 99%, powder T7394 25g $313
N,N,N′,N′-Tetramethyl-1,4-phenylenediamine for synthesis 8.21101 5G $60.5
N,N,N′,N′-Tetramethyl-1,4-phenylenediamine for synthesis 8.21101 25g $211
N,N,N′,N′-Tetramethyl-p-phenylenediamine 99%, powder T7394 5 g $123
More product size
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N,N,N',N'-Tetramethyl-1,4-phenylenediamine Properties

Melting point 49-51 °C(lit.)
Boiling point 260 °C(lit.)
Density 0.9743 (rough estimate)
refractive index 1.5700 (estimate)
Flash point >230 °F
storage temp. Store below +30°C.
form powder
pka 5.92±0.12(Predicted)
color off-white to gray
Water Solubility slightly in cold, more in hot water
Sensitive Air & Light Sensitive
Merck 14,9228
BRN 1564025
Stability Stable, but may be air or light sensitive. Combustible. Incompatible with acids, acid chlorides, acid anhydrides, oxidizing agents.
InChI 1S/C10H16N2/c1-11(2)9-5-7-10(8-6-9)12(3)4/h5-8H,1-4H3
InChIKey CJAOGUFAAWZWNI-UHFFFAOYSA-N
SMILES CN(C)c1ccc(cc1)N(C)C
CAS DataBase Reference 100-22-1(CAS DataBase Reference)
FDA UNII P4P3AC32ZB
NIST Chemistry Reference 1,4-Benzenediamine, N,N,N',N'-tetramethyl-(100-22-1)
EPA Substance Registry System N,N,N',N'-Tetramethyl-p-phenylenediamine (100-22-1)
UNSPSC Code 12352116
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332
Precautionary statements  P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312
Hazard Codes  Xn
Risk Statements  20/21/22-40-36/37/38
Safety Statements  28-28A-36-26-22
RIDADR  UN 2811 6.1/PG 3
WGK Germany  1
RTECS  ST4200000
F  10
TSCA  TSCA listed
HazardClass  6.1(a)
PackingGroup  II
HS Code  29215190
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Toxicity LD50 oral in bird - wild: 23700ug/kg
NFPA 704
0
2 0

N,N,N',N'-Tetramethyl-1,4-phenylenediamine price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T7394 N,N,N′,N′-Tetramethyl-p-phenylenediamine 99%, powder 100-22-1 5g $123 2026-04-30 Buy
Sigma-Aldrich T7394 N,N,N′,N′-Tetramethyl-p-phenylenediamine 99%, powder 100-22-1 25g $313 2026-04-30 Buy
Sigma-Aldrich 8.21101 N,N,N′,N′-Tetramethyl-1,4-phenylenediamine for synthesis 100-22-1 5G $60.5 2026-04-30 Buy
Sigma-Aldrich 8.21101 N,N,N′,N′-Tetramethyl-1,4-phenylenediamine for synthesis 100-22-1 25g $211 2026-04-30 Buy
Sigma-Aldrich T7394 N,N,N′,N′-Tetramethyl-p-phenylenediamine 99%, powder 5 g $123 2026-03-19 Buy
Product number Packaging Price Buy
T7394 5g $123 Buy
T7394 25g $313 Buy
8.21101 5G $60.5 Buy
8.21101 25g $211 Buy
T7394 5 g $123 Buy

N,N,N',N'-Tetramethyl-1,4-phenylenediamine Chemical Properties,Uses,Production

Chemical Properties

purple to brown crystalline powder

Uses

In the form of the hydrochloride as a reagent in analytical chemistry.

Uses

N,N,N',N'-Tetramethyl-p-phenylenediamine is a reducing co-substrate for heme peroxidases. It is used for detection of peroxidases on polyacrylamide gels.

Synthesis Reference(s)

The Journal of Organic Chemistry, 29, p. 488, 1964 DOI: 10.1021/jo01025a506

General Description

Leaflets or a drab green solid.

Air & Water Reactions

N,N,N',N'-Tetramethyl-1,4-phenylenediamine may be sensitive to air and heat. . Insoluble in water.

Reactivity Profile

N,N,N',N'-Tetramethyl-1,4-phenylenediamine can burn in air to give toxic NOx gases . Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Health Hazard

ACUTE/CHRONIC HAZARDS: When heated to decomposition N,N,N',N'-Tetramethyl-1,4-phenylenediamine emits toxic fumes. It is an irritant.

Fire Hazard

N,N,N',N'-Tetramethyl-1,4-phenylenediamine is probably combustible.

Safety Profile

Poison by ingestion. Moderatelytoxic by inhalation. Mutation data reported. When heatedto decomposition it emits toxic fumes of NOx.

Purification Methods

Crystallise the amine from pet ether or water. It can be sublimed or dried carefully in a vacuum line, and stored in the dark under nitrogen. It has been recrystallised from its melt. [Beilstein 13 H 74, 13 I 22, 13 II 40, 13 III 111, IV 107.]

N,N,N',N'-Tetramethyl-1,4-phenylenediamine Preparation Products And Raw materials

Raw materials

5-Hydroxytryptophan N,N,N',N'-Tetramethyl-1,4-phenylenediamine

Preparation Products

N,N,N',N'-Tetramethyl-1,4-phenylenediamine Suppliers

Global( 169)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21531 55
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29766 58
CONIER CHEM AND PHARMA LIMITED 		sales@conier.com China 49906 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +86-189 4982 3763 sales@tnjchem.com China 34526 58
Shanghai UCHEM Inc. 		+86-18930848214 +86-021-56762820 sales@myuchem.com China 8898 58
Baoji Guokang Healthchem Co., Ltd. 		+86-0917-3909592 +86-13892490616 gksales1@gk-bio.com China 9037 58
Hefei Hirisun Pharmatech Co., Ltd 		+8615056975894 shawn@hirisunpharm.com CHINA 9897 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 17705817739 info@dycnchem.com China 52693 58
HANGZHOU LEAP CHEM CO., LTD. 		+86-571-87711850 +8619957148339 market18@leapchem.com China 24569 58
Hebei Chuanghai Biotechnology Co., Ltd 		+86-17732866630 mina@chuanghaibio.com China 18112 58
Supplier Advantage
Henan Tianfu Chemical Co.,Ltd. 		55
career henan chemical co 		58
CONIER CHEM AND PHARMA LIMITED 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Shanghai UCHEM Inc. 		58
Baoji Guokang Healthchem Co., Ltd. 		58
Hefei Hirisun Pharmatech Co., Ltd 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58
HANGZHOU LEAP CHEM CO., LTD. 		58
Hebei Chuanghai Biotechnology Co., Ltd 		58

View Lastest Price from N,N,N',N'-Tetramethyl-1,4-phenylenediamine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N,N,N 2021-07-13 N,N,N",N"-Tetramethyl-1,4-phenylenediamine
100-22-1
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
N,N,N 2021-07-09 N,N,N",N"-Tetramethyl-1,4-phenylenediamine
100-22-1
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
N,N,N',N'-Tetramethyl-1,4-phenylenediamine pictures 2019-07-06 N,N,N',N'-Tetramethyl-1,4-phenylenediamine
100-22-1
 $8.80 1KG 97%-99% 100kg Career Henan Chemical Co

N,N,N',N'-Tetramethyl-1,4-phenylenediamine Spectrum

N,N,N',N'-Tetramethyl-1,4-phenylenediamine(100-22-1)1HNMR

100-22-1(N,N,N',N'-Tetramethyl-1,4-phenylenediamine)Related Search:

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1,4-BIS(DIMETHYLAMINO)BENZENE 1,4-bis(dimethylamino)-benzen 4-Benzenediamine,N,N,N’,N’-tetramethyl-1 Benzene, 1,4-bis(dimethylamino)- N,N,N',N'-Tetramethyl-p-fenylendiamin n,n,n’,n’-tetramethyl-4-benzenediamine N,N,N’,N’-Tetramethyl-benzene-1,4-diamine n,n,n’,n’-tetramethyl-p-fenylendiamin N,N,N’,N’-Tetramethyl-p-phenyl n,n,n’,n’-tetramethyl-p-phenylenediamin N,N,N',N'-4METH-P-PHENDIA 2HCL p-Bis(dimethylamino)benzene p-Phenylenediamine, N,N,N',N'-tetramethyl- Tetramethyl-p-phenyldiamine TL 85 tl85 wurster’sblue 1,4-Bis(dimethylamino)benzene~Wursters Blue N,N,N,N-tetramethyl-P-*phenylenediamine free ba N,N,N',N'-TETRAMETHYL-P-*PHENYLENEDIAMIN E FREE BASE N,N,N',N'-Tetramethyl-p-phenylenediamine, 98+% 1,4-Benzenediamine, N,N,N,N-tetramethyl- N,N,N?N?Tetramethyl-p-phenylene- diamine, [1,4-Bis(dimethylamino)benzene TETRAMETHYLPARA-PHENYLENEDIAMINE 1,4-BenzenediaMine, N1,N1,N4,N4-tetraMethyl- N,N,N',N'-TetraMethyl-p-phenylenediaMine 99%, powder WursterBlue] N,N,N',N'Tetramethyl-p-phenylenediamine≥ 99%(Titration) N,N,N',N'-Tetramethyl-1,4-phenylenediamine for synthesis 1-N,1-N,4-N,4-N-tetramethylbenzene-1,4-diamine N,N,N',N'-TETRAMETHYL-1,4-PHENYLENEDIAMI 4-(Dimethylamino)-N,N-dimethylaniline 100-22-1 C10H16N2 N,N,N',N'-Tetramethyl-1,4-phenylenediamine -Amino-2-methyl-123H-tetrazole N,N,N',N'-Tetramethyl-1,4-phenylenediamine N,N,N,N-Tetramethyl-1,4-phenylenediamine , N,N,N′,N′-Tetramethyl-p-phenylenediamine N1,N1,N4,N4-Tetramethyl-1,4-benzenediamine N,N,N',N'-Tetramethyl-1,4-phenylenediamine N,N,N',N'-Tetramethyl-1,4-Benzenediamine N1,N1,N4,N4-Tetramethylbenzene-1,4-diamine N,N,N',N'-Tetramethyl-p-phenylenediamine N,N,N′,N′-Tetramethyl-p-phenylenediamine Tetramethyl-p-phenylenediamine TMPPD Wurster's blue 100-22-1 22488-01-9 C6H4NCH322 Building Blocks Organic Building Blocks Nitrogen Compounds Polyamines