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ChemicalBook >> CAS DataBase List >>N,N,N',N'-Tetramethyl-1,4-phenylenediamine

N,N,N',N'-Tetramethyl-1,4-phenylenediamine

N,N,N',N'-Tetramethyl-1,4-phenylenediamine Structure
N,N,N',N'-Tetramethyl-1,4-phenylenediamine structure
CAS No.
100-22-1
Chemical Name:
N,N,N',N'-Tetramethyl-1,4-phenylenediamine
Synonyms
N,N,N',N'-Tetramethyl-p-phenylenediamine;TMPPD;Wurster's blue;Tetramethyl-p-phenylenediamine;N,N,N',N'-Tetramethyl-1,4-Benzenediamine;N,N,N′,N′-Tetramethyl-p-phenylenediamine;N1,N1,N4,N4-Tetramethylbenzene-1,4-diamine;tl85;TL 85;WursterBlue]
CBNumber:
CB2300445
Molecular Formula:
C10H16N2
Molecular Weight:
164.25
MDL Number:
MFCD00008309
MOL File:
100-22-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 00:06:38
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N,N,N',N'-Tetramethyl-1,4-phenylenediamine Properties

Melting point 49-51 °C(lit.)
Boiling point 260 °C(lit.)
Density 0.9743 (rough estimate)
refractive index 1.5700 (estimate)
Flash point >230 °F
storage temp. Store below +30°C.
form powder
pka 5.92±0.12(Predicted)
color off-white to gray
Water Solubility slightly in cold, more in hot water
Sensitive Air & Light Sensitive
Merck 14,9228
BRN 1564025
Stability Stable, but may be air or light sensitive. Combustible. Incompatible with acids, acid chlorides, acid anhydrides, oxidizing agents.
InChI 1S/C10H16N2/c1-11(2)9-5-7-10(8-6-9)12(3)4/h5-8H,1-4H3
InChIKey CJAOGUFAAWZWNI-UHFFFAOYSA-N
SMILES CN(C)c1ccc(cc1)N(C)C
CAS DataBase Reference 100-22-1(CAS DataBase Reference)
FDA UNII P4P3AC32ZB
NIST Chemistry Reference 1,4-Benzenediamine, N,N,N',N'-tetramethyl-(100-22-1)
EPA Substance Registry System N,N,N',N'-Tetramethyl-p-phenylenediamine (100-22-1)
UNSPSC Code 12352116
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332
Precautionary statements  P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312
Hazard Codes  Xn
Risk Statements  20/21/22-40-36/37/38
Safety Statements  28-28A-36-26-22
RIDADR  UN 2811 6.1/PG 3
WGK Germany  1
RTECS  ST4200000
F  10
TSCA  TSCA listed
HazardClass  6.1(a)
PackingGroup  II
HS Code  29215190
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Toxicity LD50 oral in bird - wild: 23700ug/kg
NFPA 704
0
2 0

N,N,N',N'-Tetramethyl-1,4-phenylenediamine price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T7394 N,N,N′,N′-Tetramethyl-p-phenylenediamine 99%, powder 100-22-1 5g $123 2026-04-30 Buy
Sigma-Aldrich T7394 N,N,N′,N′-Tetramethyl-p-phenylenediamine 99%, powder 100-22-1 25g $313 2026-04-30 Buy
Sigma-Aldrich 8.21101 N,N,N′,N′-Tetramethyl-1,4-phenylenediamine for synthesis 100-22-1 5G $60.5 2026-04-30 Buy
Sigma-Aldrich 8.21101 N,N,N′,N′-Tetramethyl-1,4-phenylenediamine for synthesis 100-22-1 25g $211 2026-04-30 Buy
Sigma-Aldrich T7394 N,N,N′,N′-Tetramethyl-p-phenylenediamine 99%, powder 5 g $123 2026-03-19 Buy
Product number Packaging Price Buy
T7394 5g $123 Buy
T7394 25g $313 Buy
8.21101 5G $60.5 Buy
8.21101 25g $211 Buy
T7394 5 g $123 Buy

N,N,N',N'-Tetramethyl-1,4-phenylenediamine Chemical Properties,Uses,Production

Chemical Properties

purple to brown crystalline powder

Uses

In the form of the hydrochloride as a reagent in analytical chemistry.

Uses

N,N,N',N'-Tetramethyl-p-phenylenediamine is a reducing co-substrate for heme peroxidases. It is used for detection of peroxidases on polyacrylamide gels.

Synthesis Reference(s)

The Journal of Organic Chemistry, 29, p. 488, 1964 DOI: 10.1021/jo01025a506

General Description

Leaflets or a drab green solid.

Air & Water Reactions

N,N,N',N'-Tetramethyl-1,4-phenylenediamine may be sensitive to air and heat. . Insoluble in water.

Reactivity Profile

N,N,N',N'-Tetramethyl-1,4-phenylenediamine can burn in air to give toxic NOx gases . Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Health Hazard

ACUTE/CHRONIC HAZARDS: When heated to decomposition N,N,N',N'-Tetramethyl-1,4-phenylenediamine emits toxic fumes. It is an irritant.

Fire Hazard

N,N,N',N'-Tetramethyl-1,4-phenylenediamine is probably combustible.

Safety Profile

Poison by ingestion. Moderatelytoxic by inhalation. Mutation data reported. When heatedto decomposition it emits toxic fumes of NOx.

Purification Methods

Crystallise the amine from pet ether or water. It can be sublimed or dried carefully in a vacuum line, and stored in the dark under nitrogen. It has been recrystallised from its melt. [Beilstein 13 H 74, 13 I 22, 13 II 40, 13 III 111, IV 107.]

N,N,N',N'-Tetramethyl-1,4-phenylenediamine Preparation Products And Raw materials

Raw materials

5-Hydroxytryptophan N,N,N',N'-Tetramethyl-1,4-phenylenediamine

Preparation Products

N,N,N',N'-Tetramethyl-1,4-phenylenediamine Suppliers

Global( 170)Suppliers
Supplier Tel Email Country ProdList Advantage
Suzhou Highfine Biotech Co., Ltd 0512-69209928 18796809688 zhouyingxiang@highfine.com China 1846 58
Heze Chuangfa Biotechnology Co., Ltd. 15864743015 15864743015 1187939516@qq.com China 144 58
Shanghai Fengtian Biotechnology Co., Ltd 021-17514032201 17514032201 17514032201@163.com China 75 58
Creasyn Finechem(Tianjin) Co., Ltd. 022-83946278 13820372920 sales@creasyn.com China 968 68
Nanbu County Chengxin Technology Co., Ltd. 0838-5675166 15883665058 nbcxkj@126.com China 956 55
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Supplier Advantage
Suzhou Highfine Biotech Co., Ltd 58
Heze Chuangfa Biotechnology Co., Ltd. 58
Shanghai Fengtian Biotechnology Co., Ltd 58
Creasyn Finechem(Tianjin) Co., Ltd. 68
Nanbu County Chengxin Technology Co., Ltd. 55
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Alfa Aesar 84
Energy Chemical 61

View Lastest Price from N,N,N',N'-Tetramethyl-1,4-phenylenediamine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N,N,N 2021-07-13 N,N,N",N"-Tetramethyl-1,4-phenylenediamine
100-22-1
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
N,N,N 2021-07-09 N,N,N",N"-Tetramethyl-1,4-phenylenediamine
100-22-1
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
N,N,N',N'-Tetramethyl-1,4-phenylenediamine pictures 2019-07-06 N,N,N',N'-Tetramethyl-1,4-phenylenediamine
100-22-1
 $8.80 1KG 97%-99% 100kg Career Henan Chemical Co

N,N,N',N'-Tetramethyl-1,4-phenylenediamine Spectrum

N,N,N',N'-Tetramethyl-1,4-phenylenediamine(100-22-1)1HNMR

100-22-1(N,N,N',N'-Tetramethyl-1,4-phenylenediamine)Related Search:

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1of4

1,4-BIS(DIMETHYLAMINO)BENZENE 1,4-bis(dimethylamino)-benzen 4-Benzenediamine,N,N,N’,N’-tetramethyl-1 Benzene, 1,4-bis(dimethylamino)- N,N,N',N'-Tetramethyl-p-fenylendiamin n,n,n’,n’-tetramethyl-4-benzenediamine N,N,N’,N’-Tetramethyl-benzene-1,4-diamine n,n,n’,n’-tetramethyl-p-fenylendiamin N,N,N’,N’-Tetramethyl-p-phenyl n,n,n’,n’-tetramethyl-p-phenylenediamin N,N,N',N'-4METH-P-PHENDIA 2HCL p-Bis(dimethylamino)benzene p-Phenylenediamine, N,N,N',N'-tetramethyl- Tetramethyl-p-phenyldiamine TL 85 tl85 wurster’sblue 1,4-Bis(dimethylamino)benzene~Wursters Blue N,N,N,N-tetramethyl-P-*phenylenediamine free ba N,N,N',N'-TETRAMETHYL-P-*PHENYLENEDIAMIN E FREE BASE N,N,N',N'-Tetramethyl-p-phenylenediamine, 98+% 1,4-Benzenediamine, N,N,N,N-tetramethyl- N,N,N?N?Tetramethyl-p-phenylene- diamine, [1,4-Bis(dimethylamino)benzene TETRAMETHYLPARA-PHENYLENEDIAMINE 1,4-BenzenediaMine, N1,N1,N4,N4-tetraMethyl- N,N,N',N'-TetraMethyl-p-phenylenediaMine 99%, powder WursterBlue] N,N,N',N'Tetramethyl-p-phenylenediamine≥ 99%(Titration) N,N,N',N'-Tetramethyl-1,4-phenylenediamine for synthesis 1-N,1-N,4-N,4-N-tetramethylbenzene-1,4-diamine N,N,N',N'-TETRAMETHYL-1,4-PHENYLENEDIAMI 4-(Dimethylamino)-N,N-dimethylaniline 100-22-1 C10H16N2 N,N,N',N'-Tetramethyl-1,4-phenylenediamine -Amino-2-methyl-123H-tetrazole N,N,N',N'-Tetramethyl-1,4-phenylenediamine N,N,N,N-Tetramethyl-1,4-phenylenediamine , N,N,N′,N′-Tetramethyl-p-phenylenediamine N1,N1,N4,N4-Tetramethyl-1,4-benzenediamine N,N,N',N'-Tetramethyl-1,4-phenylenediamine N,N,N',N'-Tetramethyl-1,4-Benzenediamine N1,N1,N4,N4-Tetramethylbenzene-1,4-diamine N,N,N',N'-Tetramethyl-p-phenylenediamine N,N,N′,N′-Tetramethyl-p-phenylenediamine Tetramethyl-p-phenylenediamine TMPPD Wurster's blue 100-22-1 22488-01-9 C6H4NCH322 Building Blocks Organic Building Blocks Nitrogen Compounds Polyamines